Phytochemical Analysis of Kudarkirumi Naasini Chooranam Formulation Against Intestinal Worms

Abstract

Kudarkirumi Naasini Chooranam is a traditional Siddha-based herbal formulation indicated for the management of intestinal worm infestations. The present study was undertaken to characterize the phytochemical profile and assess the medicinal potential of this formulation. Standardized analytical procedures were employed to perform a qualitative phytochemical evaluation of the formulation, aiming to identify its constituent secondary metabolites. The detection of alkaloids, terpenoids, and phenolic compounds substantiates the traditional use of the formulation, as these classes of compounds are frequently associated with anthelmintic efficacy. The identified phytochemicals act by inhibiting the energy production and structural maintenance of the worms, leading to a loss of viability and subsequent clearance from the host. The combination of multiple herbal ingredients in the formulation may also produce a synergistic effect, enhancing its therapeutic efficacy. The presence of these active compounds provides a scientific basis for the traditional use of Kudarkirumi Naasini Chooranam in Siddha medicine. The findings of this investigation demonstrate that the formulation possesses potent anthelmintic activity, suggesting its potential as a natural therapeutic agent for the clinical management of intestinal worm infestations. However, further detailed pharmacological and clinical investigations are required to establish its safety and efficacy.