IN VIVO STUDY OF EFFICACY OF TRAILOKYASUNDAR RASA IN CHRONIC MYELOID LEUKEMIA

  • *Paras Dilipkumar Golecha Director, Brahmanath Pharma Pvt. Ltd., Panvel, Navi Mumbai, Maharashtra
  • Ninad Sathe Professor, Department of Rasashastra & Bhaishajyakalpana, YMT Ayurvedic Medical College, Kharghar, Navi Mumbai
  • Sheela Pargunde Professor & HOD, Department of Rasashastra & Bhaishajyakalpana, YMT Ayurvedic Medical College, Kharghar, Navi Mumbai
  • Siddhisha Kurve Technical officer, SDL India Ltd, Khetwadi, Mumbai
Keywords: Rasa aushadhis, Trailokyasundar rasa, Panduroga, Chronic Myeloid Leukemia.

Abstract

Trailokyasundar rasa is one of the Rasakalpa which is explained in Rasaratnasamucchaya, and is suggestive of its efficacy in Pandu roga. Pandu roga is a Pitta pradhanavyadhi in which Rasadhatu and raktadhatu are mainly affected. According to modern texts, all disorders of vitiated digestion, absorption and assimilation can be considered under Pandu. According to modern texts, all disorders of vitiated digestion, absorption and assimilation can be considered under Pandu. Therefore, it can be said that Pandu is a very broad term comprising various rasa and Raktpradoshajvikara such as anaemia, megaloblastic anaemia, blood disorders, leukemia’s etc.

Material and method: On the basis of this information animal models were planned to evaluate the effect of self-prepared test drug. Study duration -1 month

Discussion and results: The activity of Trailokyasundar rasa is highly significant by reducing tumour volume and growth inhibition in animal models of chronic myeloid leukemia. On the 29thday of the experiment tumour size of the control group was 20.05 mm. comparatively in the study group, mean tumour size was of 5.26 mm. Also it prevented decrease in the platelet count and Hb% as compared to untreated mice of CML. Rate of increment of WBC’s was also comparatively reduced in Trailokyasundar rasa treated mice.

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Author Biography

*Paras Dilipkumar Golecha, Director, Brahmanath Pharma Pvt. Ltd., Panvel, Navi Mumbai, Maharashtra
Published
18-08-2018
How to Cite
Golecha, *Paras D., Sathe, N., Pargunde, S., & Kurve, S. (2018). IN VIVO STUDY OF EFFICACY OF TRAILOKYASUNDAR RASA IN CHRONIC MYELOID LEUKEMIA. International Journal of Ayurveda and Pharma Research, 6(7). Retrieved from https://ijapr.in/index.php/ijapr/article/view/946
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Articles