Effectiveness of Viyakkirathi Kashayam in the Treatment of Azhal Thalai Nokkadu (Sinusitis)

Abstract

Sinusitis or inflammation of sinus mucosa, is a very common complaint encountered in clinical practice and affects individuals of all age groups. The signs and symptoms of Azhal Thalai Nokkadu described in siddha text Yugi Vaithiya Chinthamani including lacrimation, nasal obstruction, headache, rhinorrhea, cough, and loss of taste closely correlate with clinical feature of sinusitis. This study aims to evaluate the effectiveness of the siddha formulation Viyakkirathi Kashayam in the treatment of Azhal Thalai Nokkadu (sinusitis), using the Adelaide Disease Severity Score. Method: This was a descriptive case series conducted on 20 patients diagnosed with sinusitis over a period of 30 days. Ethical approval was obtained from the Institutional Ethics Committee (IEC No: GSMC-XIII IEC-Br-I/09/24.05.2024). The study was prospectively registered in the Clinical trials Registry of India (CTRI Reg No: CTRI/2024/06/069416). The trial intervention consisted of Viyakkirathi Kashayam 50ml twice daily along with Thippili Chooranam (800mg) was given for 30 days. Result: Biostatistical analysis of Adelaide Disease Severity Score (ADSS) before and after treatment was performed using paired t-test n SPSS version 21. The trail intervention demonstrated a statistically significant reduction in ADSS scores following treatment (p<0.001). No adverse effect of the trial drugs were observed during the study period. Conclusion: The findings suggest that Viyakkirathi Kashayam is significantly effective in the management of sinusitis.