Healing Effect of Madhuchishtadi Ghritha Against Patoladi Taila Topically in Agni Dagdha Vrana After Corn Excision (Kadara) - A Comparative Study

Abstract

Agnidagdha Vrana (burn wound) is a common condition encountered both as a pathological lesion and as a therapeutic outcome of procedures such as Agnikarma. Kadara (corn) excision followed by Taila Dahana produces an Agnidagdha Vrana. Classical Ayurvedic texts recommend various preparations for Vrana Ropana, among which Madhuchishtadi Ghritha, described by Acharya Susrutha as “Sarvesham Agnidagdhanam etath Ropanam Uttamam,” is indicated as an excellent remedy for all types of Agnidagdha Vrana. Patoladi Taila, mentioned in Bhavaprakasha, is another established formulation with Pittahara, Shothahara, and Ropana properties. Objectives: To evaluate the healing effect of Madhuchishtadi ghritha in comparison with Patoladi taila topically in Agni dagdha vrana after corn excision. Materials and methods: A comparative interventional study with two groups was conducted. 15 participants of age group 20-70 years of both sexes who satisfied the inclusion and exclusion criteria were selected for the study. In Agnidagdha vrana after Kadara excision Madhuchishtadi ghritha, was applied in trial group where as Patoladi taila, in control group. The treatment period was maximum 35 days or up to wound healing. Periodic assessments were made on wound diameter, depth, discharge, pain, and burning sensation. Results: Both formulations produced marked improvement in all parameters, indicating their efficacy in promoting wound healing and relieving associated symptoms. Conclusion: The study highlights the therapeutic potential of classical Ayurvedic formulations in the management of post-Agnikarma wounds and supports their integration into contemporary clinical practice for effective and safe wound care.