The Dynamics of Kleda in Prameha and its Management Through Panchakarma

Abstract

Prameha, a complex metabolic disorder described in Ayurveda, encompasses various clinical conditions similar to diabetes mellitus and its complications. Central to its pathophysiology is the concept of Kleda- the pathological accumulation and vitiation of bodily fluid components - primarily attributed to an excess of Kapha Pitta. This abstract explores the dynamic interplay of Kleda within the Samprapti Virechana (therapeutic purgation)- of Prameha, highlighting how its formation, aggravation, and spread lead to systemic dysfunction and also emphasizes the relevance of Panchakarma therapies in the effective elimination of morbid Kleda, thereby breaking the pathogenic chain. Specifically, the Upakramas like Udwartana, Takradhara, Talapothichil, Dhanyamla dhara and Sodhana procedures like Vamana (therapeutic emesis), Virechana (purgation), Vasti (medicated enema), Raktamoksha (blood-letting) are explored for their role in detoxifying the body, restoring Doshic balance, and improving metabolic function. Tailored Sodhana protocols, when employed judiciously based on the Prakriti, Roga bala, and Roga avastha, have shown significant outcomes in reducing Kleda dushti and mitigating Prameha symptoms.