International Journal of Ayurveda and Pharma Research <div align="justify"> <p class="para1"><strong>International Journal of Ayurveda and Pharma Research (IJAPR)</strong>&nbsp;is an international peer reviewed Monthly open access Online and Print journal. The aim of the journal is to increase the impact of research in both academic and industry, with strong emphasis on quality and originality. The journal promotes to publish the articles in the field of&nbsp;<strong>Ayurveda, Siddha, Yoga, Naturopathy, Unani, Homeopathy and Allopathy</strong>&nbsp;systems of medicine and Pharmaceutical Sciences. Researchers may submit (1). Original Research Articles (2). Review articles (3). Book Reviews (4). Short Communications/ Research Letter (5). Case Report (6). Letter to the Editor/Correspondence.</p> </div> en-US (Dr B Srinivasulu M.D (Ayu.)) Sat, 18 Sep 2021 00:00:00 +0800 OJS 60 A Comparative Clinical Study to Evaluate the Effect of Shamana Sweda Followed by Nirgundi Guggulu in Vaatakantaka with Special Reference to Calcaneal Spur Amongst Female Population <p><em>Vatakantaka</em> is characterized by the pain in the heel region and included in the <em>vatavyadhi</em> by <em>Acharya Sushruta</em>. It is common in about 10% of general population. Women are twice more prevalent than men. <em>Vatakantaka</em> is mainly caused due to vitiation of <em>Vatadosha</em> and continuous pressure on the heel region. It can be co-related with Calcaneal spur. It is more prevalent in female due to life style postures like standing for longer period, wearing high heel shoes. Various treatment measures for the management of <em>Vatakantaka</em> are given in the classics of <em>Ayurveda. Siravyadha,Agnikarma</em> and <em>Eranda taila pana</em> are the main <em>chikitsa</em> of <em>Vatakantaka. Achrya Charaka</em> said <em>Vatakantaka</em> is <em>Sweda sadhya Vyadhi.</em> So in this present study, treatment is given with <em>swedana</em> followed by <em>Shamanoushadhi.</em>&nbsp; Here 40 cases of <em>Vatatakantaka</em> vis- a -vis Calcaneal spur were &nbsp;devided in to two groups and subjected to <em>Dashamula churna pinda sweda</em> &nbsp;and valuka sweda for 7 days, followed by <em>Nirgundi Guggulu </em>for 30 days. Patients &nbsp;showed significant results in subjective and objective parameters. The present clinical study has been registered as a Prospective study in clinical trials registry- India (CTRI). Register number – CTRI/2019/11/022132</p> Suma Astagimath, S G Chavan, Madhusudan Kulkarni Copyright (c) 2021 International Journal of Ayurveda and Pharma Research Sat, 18 Sep 2021 00:00:00 +0800 Vrikshayurved Methods for Disease Control in Plants with Special Reference to Onion (Allium Cepa) <p>Introduction- In today’s era due to modernization and civilization people follows modern techniques of cultivation which is starting from seed viability study then for nursery adding fertilizers in land and for treating disease and fulfilling their nutrients value adding or spraying chemical fertilizers which leads to hazards effect in environment on every creature. <em>Aacharyas</em> found natural solutions for every plant issue many years back they already mentioned in <em>Vrikshayurved</em>, how to diagnose and treat different kind of plant diseases more naturally and authentically.</p> <p>Objective- This article aims to diagnose and treat plant diseases according to<em> Vrikshayurved.</em></p> <p>Materials and methods- Study performed on Onion seedlings <em>(Allium cepa)</em> under the observation of Directorate of Onion and Garlic Research Institute, Rajgurunagar, Pune. Onion seedlings were treated by <em>Kunap jal</em> and <em>Madhuyastyadi Kwath. </em>Disease of Onion seedlings were diagnosed and treated by <em>Vrikshayurved</em> methods using <em>Kunap jal</em> and <em>Madhuyashtyadi Kwath.</em></p> <p>Results- The <em>Vrikshayurved</em> methods showed around 80-85% reduction in curling of leaves, 100% reduction in yellowish discoloration, 100 % reduction in dryness of leaves.</p> <p><em>Vrikshayurved </em>intervention improved growth rate drastically.</p> <p>Conclusion- <em>Vrikshayurved</em> intervention improved curling, dryness and yellowish discoloration of leaves significantly. It also doubled growth rate of the onion seedlings. It indicates that <em>Vrikshayurved</em> methods are applicable in today’s era.</p> More Shweta Vinod, Avalaskar Amit D, Mahajan Vijay, Sogam Onkar Anant Copyright (c) 2021 International Journal of Ayurveda and Pharma Research Sat, 18 Sep 2021 00:00:00 +0800 Herbal Lepa Formulation Preparation and its Evaluation <p>The concept of beauty is as old as humanity itself. It is the natural desire of every human being to look beautiful and glamorous. The beauty and glamour are because of perfect skin. Herbs have been used for beautification from historic times and have also been described in Ayurvedic literature. Herbs as whole or herbal extracts have been used to treat the various ailments of the skin, hair, body odor, and overall beautification. The demand for Ayurveda in cosmetology is established because it is effective, cheaper, and long-lasting without any side effects. The present study aimed to formulate and evaluate the beneficial effect of herbal Lepa formulation for beautification. Beautification in terms of skin lightening, removal of scars and pigmentation, dark circles, and ultimately healthy glowing skin. The advantage of herbal cosmetics compared to chemical products is they are non-toxic in nature. The Lepa formulation is the suitable dosage form prepared using various natural components in the appropriate and desired quantity for better effectiveness. The formulation has shown significant improvement in various skin problems, including skin pigmentation, melasma, acne marks, and skin lightening effect with no further moisturizing cream requirements.</p> Tejaswini Singh Copyright (c) 2021 International Journal of Ayurveda and Pharma Research Sat, 18 Sep 2021 00:00:00 +0800 Phyto-Pharmacognostical Standardization with HPTLC Fingerprinting of Root of Citraka (Plumbago zeylanica L.) <p><strong>Background: </strong><em>Citraka</em> or <em>Sveta Citraka</em> (<em>Plumbago zeylanica </em>L.) is an important medicinal plant mentioned in Ayurvedic classics, belongs to the family Plumbaginaceae. The root of the plant exhibits medicinal properties. It has a broad range of pharmacological activities, including anti-inflammatory, antibacterial, antifungal, anticancer, antidiabetic, antioxidant, hepatoprotective, wound healing and cytotoxic.</p> <p><strong>Objective: </strong>The aim of the study was to evaluate phyto-pharmacognostical standardization with HPTLC fingerprinting of root of <em>P. zeylanica</em>, one of the most accepted and beneficial medicinal plant in <em>Ayurveda</em>.</p> <p><strong>Materials and Methods: </strong><em>P. zeylanica</em> was collected from Konni, Kerala, India during the month of May 2018 and its root was studied for macroscopic, microscopic, physico-chemical, preliminary phytochemical screening and HPTLC fingerprinting following the standard protocol recommended by The Ayurvedic Pharmacopoeia of India and Quality Standards of Indian Medicinal Plants.</p> <p><strong>Results:</strong> The root is long, stout, cylindrical and reddish to dark brown in colour. The transverse section of root showed 5-7 rows of small cubical or rectangular celled cork with light yellow walls, polygonal or slightly tangentially elongated cortex cells containing starch grains and coloured contents, phloem containing small groups of fibres, radially arranged xylem vessels and narrow, 1-4 seriate medullary rays. Physico-chemical analysis showed water soluble extractive value as 26.11±0.01 w/w and alcohol soluble extractive value as 15.85±0.00 w/w. Preliminary phytochemical analysis of root decoction showed the presence of alkaloids, carbohydrates, tannins, saponins, resin and quinones.</p> <p><strong>Conclusion: </strong>The information obtained from this research work may be useful to establish the botanical as well as analytical standards for the root of <em>P. zeylanica</em>.</p> Akhilraj A.R, Rukmini S, Amalraj A.R Copyright (c) 2021 International Journal of Ayurveda and Pharma Research Sat, 18 Sep 2021 00:00:00 +0800 Vrikshayurved Plantation Techniques: A Review <p>Use of chemicals for plant growth and its management has led to soil and water pollution. It has ultimately affected the quality of medicinal plants.&nbsp; In the other hand <em>Vrikshayurved</em> (science of plant life) have fully organic and time tested methods to deal with entire plant life. It mostly emphasizes on the selection of land, seed collection, seed treatment, different plant propagation methods, irrigation, manure, plant protection, plant disease management, crop harvesting and storage of produce. Thus, <em>Vrikshayurved </em>encompasses both agriculture and forestry.</p> <p>Materials and method- Collection and compilation of useful information has been done from concerned articles and texts of Ayurved and <em>Vrikshayurved</em> texts such as <em>Surpala’s Vrikshayurved</em>, <em>Upavan</em> <em>Vinod</em>, <em>Varahamihir’s</em> <em>Brihat</em> <em>Samhita</em>, <em>Charak Samhita</em> and <em>Sushruta</em> <em>Samhita.</em></p> <p>Discussion and Conclusion- This article represents concise information of <em>Vrikshayurved</em> plantation techniques for seed propagation, grafting, stem propagation, tuber propagation and plant transplantation. All these methods are affordable, natural, and chemical free. All substances used by <em>Vrikshayurved</em> methodology have its Ayurvedic significance. Thus, <em>Vrikshayurved</em> and <em>Manushya</em> <em>Ayurved</em> are interdependent. Use of <em>Vrikshayurved</em> in modern agriculture and forestry can result in better agriculture system and sustainable forestry. Hence formation of standard guidelines for <em>Vrikshayurved</em> methodologies through research work is mandatory for better tomorrow.</p> Abnave Prajkta Dilip, Avalaskar Amit D Copyright (c) 2021 International Journal of Ayurveda and Pharma Research Sat, 18 Sep 2021 00:00:00 +0800 Effective Management of Hypothyroidism by Using Ayurvedic Interventions: A Case Report <p>Hypothyroidism is an endocrine disorder that mainly occurs due to insufficient thyroid gland stimulation or primary gland failure by the pituitary or hypothalamus gland. Symptoms of hypothyroidism include fatigue, gastric trouble, face puffiness with edematous eyelids, retarded nail growth, weight gain, hoarseness of voice, decreased libido, pallor, dry skin, dry hair, alopecia, constipation, abnormal menstrual cycle, muscle cramps, myalgia etc. A 30-year-old married Hindu, non-alcoholic, non-smoking male patient visited OPD of Shuddhi Ayurveda Clinic, Jeena Sikho Lifecare Pvt. Ltd. Noida on 18 November 2020 with known case of subclinical hypothyroidism. On the basis of clinical diagnosis and laboratory investigations, ayurvedic medicines having action on thyroid gland and digestion improvement were prescribed for over a period of six months. After this ayurvedic medicinal treatment for four months i.e. from November 2020 to February 2021, significant results were noted in terms of reduction in level of increased TSH. TSH level was significantly reduced from 181µIU/ml to 0.11 µIU/ml within two months of ayurvedic treatment. Then, there was a mild increase in the TSH level when patient was tested for TFT after four months i.e. on 21<sup>st</sup> of June 2021, investigated level of TSH was 5.59 µIU/ml. Overall, a satisfactory result was observed in patient clinical conditions proving significant efficacy of ayurvedic treatment.</p> Bhawna Walia, Manish Grover, Ajeet Pratap Singh Copyright (c) 2021 International Journal of Ayurveda and Pharma Research Sat, 18 Sep 2021 00:00:00 +0800 An Insight into Ayurvedic Aspects of Male Reproductive Health with Special Reference to Preconception Care: A Narrative Review <p>Reproductive health is a universal concern, a central determinant of quality of life. Male reproductive health disorders can evolve at any phase of life, but accountability of males in maintenance of reproductive and sexual health is seemingly low. Preconception care for men discloses a reproductive health plan, health assessment, health promotion, clinical and psychosocial interventions to improve the adolescent and men in reproductive age groups. In Ayurveda the necessity of sound reproductive health for successful conception is explained under <em>dinacharya</em> (daily regimen),<em> ritucharya </em>(seasonal regimen),<em> sadvritta </em>(code of conduct for keeping good and balanced condition of body and mind),<em> panchakarma</em> (purificatory therapies)<em>, rasayana</em> (rejuvenation therapy) and<em> vajikarana </em>(aphrodisiac therapy). Research studies paved less limelight to address the need for preserving the same right from an early phase of life. It is the privilege to avail the possibilities from both ayurvedic and contemporary science to upgrade reproductive health, which in turn enhances positive eugenics. This review is intended with an attempt to detail the ayurvedic aspects of male reproductive health with special reference to preconception care.</p> Sujatha Atheena, Krishnarajabhatt Hemavathi Shivapura, Unnikrishnan Parvathy, Muraleedharan Anjaly Copyright (c) 2021 International Journal of Ayurveda and Pharma Research Sat, 18 Sep 2021 00:00:00 +0800 Utility of Vajikarana in General Health- A Review <p><strong>Objective</strong><em>: Vajikarana</em> or <em>Vrishya chikitsa</em> is the branch of <em>Ayurveda</em> dealing with reproductive health and virility. Though this branch makes use of drugs under the category of aphrodisiac, the multifaceted effect of those is underexplored. The properties of disease prevention and restoration of health might be the attribute benefited in sexual health too. This paper intends to explore the general health benefits of <em>Vajikarana </em>drugs.</p> <p><strong>Materials and Methods</strong>:&nbsp; Data related to the aphrodisiac drugs are located in classical texts of Ayurveda and online journals with keywords “<em>Vajikarana,</em> <em>Ayurveda</em>, aphrodisiacs, neuro-endocrine immune system, <em>Vrishya chiktsa, Ojas</em> and sex hormones”. The relevant scripts were selected and appropriate data from 8 articles and 18 chapters were extracted for the final manuscript construction.</p> <p><strong>Results</strong>: The drugs like <em>Ashwgandha, Shatavari, Atmagupta, Sweta musali</em> and <em>Masha</em> proved to have a neuro-endocrinological effects, psycho-neuro-immunological effects, anti-inflammatory and anti-oxidant properties apart from aphrodisiac effects. It stabilizes <em>Tridosha</em>, <em>Saptadathu</em> and eventually <em>Ojas,</em> and calms mental faculties.</p> <p><strong>Conclusion</strong>: The proper use of the <em>Vajikarana</em> formulations imparts qualities like good physique, potency, strength, and complexion. This benefits of <em>Vajikarana</em> can be incorporated into other health conditions also. The practice of <em>Vajikarana</em> corrects the deformities of reproductive systems and in turn balances other body functions. Advanced research on the health benefits and enhancing sexual potency of women should be carried out on <em>Vajikarana</em> therapy. This will aid prevention of diseases which is a major health standpoint in the current day scenario.</p> Anusree Dileep, Sreelekshmi.S, Vandana Rani M, Delvin.T.Robin, Meera.S Copyright (c) 2021 International Journal of Ayurveda and Pharma Research Sat, 18 Sep 2021 00:00:00 +0800 Role of Ayurvedic Anticoagulant and Antioxidant Treatment in Covid-19 <p>Corona virus disease is caused by severe acute respiratory syndrome Corona virus 2[SARS-CoV-2] infections attacking multisystem of the human body at a time, of which respiratory system, immune system and circulatory system are most affected. The complications of the disease arise or it becomes more pronounced, after the cytokinine storm phase becomes established leading to hypercoagulative state affecting the circulatory and respiratory system. In Ayurveda, there is a holistic approach in treating the disease and the body as a whole. Drugs such as Haridra, Tulasi, Guduchi, Yashtimadhu, Twak, Triphala, Lavang, Maricha, Pippali etc and few Visha Dravyas like Langali, Dravanti etc can be used a single drug or a group of drugs with their phytochemical properties and active principles leading to delay and prevention of hyper coagulable states thereby preventing the cascade of complications caused by COVID, additionally having anti-inflammatory and immune-modulatory effect. Scientific research on these drugs may reveal a new approach for management and prevention of COVID related complications and can be a subject of future research interest.</p> Amrut.S. Salunke, Adarsh Ramkalap Sharma, Sonali Sunil Tadasarkar Copyright (c) 2021 International Journal of Ayurveda and Pharma Research Sat, 18 Sep 2021 00:00:00 +0800 Role of Adolescence Lifestyle in Cardio Vascular Disease-An Ayurvedic Perspective <p>Heart disease in the adolescent age group has a unique spectrum. Among all adolescents, risk factors like obesity, an inactive lifestyle, smoking, high blood pressure, and high cholesterol that have a direct relationship on the probability of having cardiac disease later in life. According to Ayurvedic literature, <em>Hridaya</em> is the <em>mula</em> of <em>RasavahaSrotas</em> . The vitiation of this system may lead to diseases such as <em>Sthoulya, Hridroga</em> etc. The role of <em>VyanaVayu</em> and <em>Ojus</em> which contribute significantly to the health and disease of cardio-vascular system. Cardiac risk factors can be prevented or managed by lifestyle including principles of <em>Dinacharya, Ritucharya and sadvrtta</em>. With rapid economic development and increasing urbanization of lifestyle in the past few decades, prevalence of these diseases has reached alarming proportions among Indians in the recent years. So, this presentation is an effort to throw light on the role of adolescence life style in cardiac diseases.</p> Anoop AK, Nithya AK, Sandhya CV Copyright (c) 2021 International Journal of Ayurveda and Pharma Research Sat, 18 Sep 2021 00:00:00 +0800 A Drug Review on Cheppu Nerunjil Ennai-A Siddha Herbal Formulation in the Management of Sooli Kanam (Childhood Asthma) In Children <p>Siddha system is the oldest and well documented Indian traditional System of medicine. The term Siddha means achieving perfection. Siddhars were saints who achieved better results in medicine. Siddhars are human beings with super intellectual capacity. Asthma is one of the most common chronic diseases of childhood. Most children develop asthma in early age. Prevalence of asthma in children increases due to growing urbanization, modernization, overcrowding and changing lifestyles. Asthma is a non communicable disease characterized by recurrent wheezing, breathlessness, chest tightness, and coughing. The symptoms of <em>Soolikanam</em> nearly correlate with childhood asthma. Numerous medicines for <em>Soolikanam</em> (childhood asthma) are explained in Siddha text. <em>Cheppu</em> <em>Nerunjil</em> <em>Ennai</em> is one of the herbal formulations indicated for <em>Soolikanam</em>. <em>Cheppu</em> <em>nerunjil</em> <em>ennai</em> was mentioned in <em>Balavagadam</em> <em>siddha</em> text book. This trial drug <em>Cheppu</em> <em>Nerunjil</em> <em>Ennai</em> comprises of eight herbal ingredients like Indigofera linnaei, Desmodium triflorum, Euphorbia parviflora, Cassia tora, Vigna trilobata, Sesbania grandiflora, Allium cepa. The herbal ingredients of <em>Cheppu</em> <em>Nerunjil</em> <em>Ennai</em> possess anti asthmatic activity, anti spasmodic, anti allergic activity, anti oxidant and immunomodulatory activity. This review article reflects history, properties, chemical constituents, pharmacological activities and several medicinal uses of the drug <em>Cheppu</em> <em>Nerunjil</em> <em>Ennai</em> on <em>Soolikanam</em>. This review further focuses to improve the research on Siddha herbal medicines.</p> Brindha. A, Meenakshi Sundaram.M, Meenakumari.R Copyright (c) 2021 International Journal of Ayurveda and Pharma Research Sat, 18 Sep 2021 00:00:00 +0800 Current Honey Market in India - Volume and Value <p>Honey is known for its dietary as well as medicinal uses in India. India was leading the global honey business till the colonial rule took over the honey into its hands. The beehives were traditionally harvested till 19<sup>th</sup> century and Europeans as well as British introduced beekeeping in India. Since then, beekeeping has become another way of livelihood for the rural communities and tribes. However, the activity remains unorganized for various reasons including logistics and migration. Gradually, National Bee Board was established and recently National Beekeeping and Honey Mission is launched. It is estimated that more than 5 lakh farmers / beekeepers are associated with the honey production in this country. The data on the volume and value of honey is still missing therefore an attempt has been made in this paper by using the top to bottom approach. This data would help the traders as well as the government to focus on the financials of honey trade.</p> Ramashrit Singh Copyright (c) 2021 International Journal of Ayurveda and Pharma Research Sat, 18 Sep 2021 00:00:00 +0800 Role of Agnikarma in Pain Management of Various Musculoskeletal Disorders: A Review Study <p><em>Agnikarma </em>is one of the important Para-surgical procedures described in Ayurveda, which has been widely used in the clinical practice now days. <em>Sushruta</em> has given detail description about <em>Agnikarma.</em> Superiority of <em>Agnikarma </em>over other the treatment modalities are timely described by our ancienter because of its <em>Apunrabhavatva</em> i.e., no recurrence property. Pain (<em>Ruja</em>) is the cardinal feature of most of the musculoskeletal disorders and it can affect the quality of life. In modern lifestyle, patient needs instant relief from pain. Treatment available in modern medicine commonly NSAID’s (Nonsteroidal anti-inflammatory drugs) but it has some hazardous effects on body. This review is an attempt has been made to study various research article, analyzed the role of<em> Agnikarma </em>and its applicability on various painful disorders which help to gain best knowledge about <em>Agnikarma. </em>In this article total 15 research works from various journals have been studied conducted on <em>Agnikarma.</em> <em>Agnikarma</em> was found very important tool in pain management of many musculoskeletal disorders. It was found safe, easy, cost-effective and OPD level procedure.</p> <p>&nbsp;</p> Badwe Yogesh, Shilvant Rishabh, Shinde Jyoti Copyright (c) 2021 International Journal of Ayurveda and Pharma Research Sat, 18 Sep 2021 00:00:00 +0800 Bhramari Pranayama: A Non-Pharmacological Approach Against Current Coronavirus Disease 19 Pandemic <p>Objective: For maintaining sound physical and mental health it is extremely beneficial for mankind to do <em>pranayama</em>. <em>Prāṇāyāma</em> bring about varying physiological and psychological effects. <em>Pranayama</em> is a branch of <em>yoga</em> practice and also considered as the fourth limb of ancient&nbsp;<em>aṣṭāṅga yoga</em>&nbsp;consisting of breathing techniques. This article aims to attain an insight on the effectiveness of Bhramari Pranayama (Bhr.P) on health and explores its need to be implemented in day to day life as a routine by all individuals in current covid 19 pandemic.</p> <p>Data source: The studies done in previous years were found using Medline, Embase, Google scholar, pub med and manual search. Studies conducted on the health effectiveness of <em>Bhramari Pranayama</em> specifically were included in this study.</p> <p>Review methods: It has been tried to keenly understand the role of <em>Bhramari pranayam</em> in particular and exploring some new concepts related to it in this review. Features of <em>Bhramari Pranayama</em> are dealt in detail with its potential effects on various systems of human body and its potentiality as a therapy tool.</p> <p>Result and conclusion: In the studies incorporated, the <em>Bhramari pranayam</em> practices have shown para-sympathetic dominance. There are some uplifting effects of <em>Bhramari pranayam</em> on different physiological systems. In holistic yoga therapy schedule pranayama is also an integral component which involves slowing down of the normal breathing rate along with an internal awareness and conscious inner focus on the respiration and reduces stress which finally causes improvement in ailments due to covid 19 pandemic.</p> Nisha Garg, Srikanta Kumar Panda Copyright (c) 2021 International Journal of Ayurveda and Pharma Research Sat, 18 Sep 2021 00:00:00 +0800 A Case Study on Ayurvedic Management of Ovarian Endometrioma <p>Menstruation is purely a natural process occurring in a woman’s body each month. It is the visible manifestation of cyclic uterine bleeding due to shedding of endometrium. Endometriosis is a common health problem for women. It is the occurrence of benign ectopic endometrial tissues outside the uterus. Ovarian endometrioma is the most common form of endometriosis. It increases the risk of ovarian cancer in reproductive age group among woman. Although most of the endometriomas are benign, some of them may undergo malignant changes. This is the case report of a 38 year old lady who presented with increased menstrual bleeding with excessive clots, dysmenorrhoea, burning micturition, and dyspareunia. On USG she was detected to have bilateral hydrosalpinx and ovarian endometrioma. Based on the clinical features presented by the patient <em>amapachana, kaphapittasamana</em> and <em>vataanulomana</em> mode of management was given. After six months of internal medications symptoms reduced considerably and there was no endometrial cysts and features of hydrosalpinx in USG.</p> Asha Sreedhar, Kavitha K.S Copyright (c) 2021 International Journal of Ayurveda and Pharma Research Sat, 18 Sep 2021 00:00:00 +0800