International Journal of Ayurveda and Pharma Research

Stability Study of Pashanbhedadi Churna Used in Treatment of Ashmari (Renal Calculi): with Respect to Baseline Microbial Diagnostic Modalities

Hetal Koriya, Meera Cholera, T.S.Dudhamal — Fri, 03 Mar 2023 00:00:00 +0800

Ashmari (Renal Calculi) is most common disease of urinary system. Ashmari or calculus looks like small gravels/stones hence they are termed as Ashmari. For the treatment of Ashmari Pashanbhedadi Churna was taken as a trial drug. As Pashanbhedadi Churna was trial drug it was necessary to check the stability. Stability of the drug is the time period from the drug production until the time it is intended to be consumed. So, present study was carried out to know the stability of Pashanbhedadi Churna and to check microbial contamination in the Pashanbhedadi Churna at different time interval. Pashanbhedadi Churna was stored in plastic bag. Microbial study of the drug was done at different climatic conditions, humidity and temperature set ups with regular intervals for a period of 11months to analyse mycological and bacteriological findings by wet mount preparation and Gram stain test respectively. Though in different climate, temperature and humidity conditions, at the end of microbial study, Churna has shown absence of microbes for approx.11 months of preparation of drug. So, it is showed that drug is stable in minimum 32°C temperature to maximum 38°C and minimum humidity 23% to maximum 74% humidity. That means stability duration of drug after preparation is approx. 11 months which showed that drug was in a standard condition. Hence it is concluded that stability test of Pashanbhedadi Churna with respect to microbiological findings was negative at room temperature, warm and cold, dry and humid conditions.

Evaluation of Antipyretic Activity of Siddha Herbomineral Formulation - Surangusa Parpam

Fri, 03 Mar 2023 00:00:00 +0800

The aim of the present study was to assess the antipyretic activity of Siddha herbo-mineral formulation Surangusa Parpam at the dose level of 15mg/kg and 35mg/kg body weight, orally, in brewer yeast induced fever model Wistar rats. Fever was induced by subcutaneous injection of 10ml/kg of 20% w/v aqueous suspension of brewer’s yeast into the nape of the rat's neck. After eighteen hours feverish animals were treated with Surangusa Parpam 15mg/kg and 35mg/kg body weight, orally, and rectal temperatures were evaluated at 0, 1, 2 and 3 hours post-treatment by inserting a well-lubricated bulb of the clinical thermometer. Surangusa Parpam showed a significant decrease in the elevated body temperature of rats that remained sustained throughout the tested time points from 1 to 3 hours in the used model. 35mg/kg body weight dose level showed significant inhibition of elevated body temperature when compared with the standard control. These results indicate that the Antipyretic activity of Surangusa Parpam and in addition to its well-established anti-inflammatory activity possesses significant antihistamine activity that may be beneficial in symptomatic relief when it is used in the therapy of allergic and inflammatory disorders.

A Case Study on Ayurvedic Management in Insulin Resistance in Polycystic Ovarian Disease

Anju G S — Fri, 03 Mar 2023 00:00:00 +0800

Polycystic ovarian disease is highly prevalent hormonal and metabolic disorder among reproductive aged women worldwide characterised by hyperandrogenism, chronic anovulation and polycystic ovaries. Insulin resistance is now recognised as a basic underlying pathology of PCOD and found in approximately 50-70% of patients. It is defined as a state in which greater than normal amounts of insulin are required to produce a quantitatively normal response. It is associated with an increased risk of various metabolic disorders including type 2 diabetes mellitus, hypertension, dyslipidaemia and cardiovascular diseases, which indicates that timely therapeutic intervention in PCOS could prevent or at-least delay the onset of type 2 diabetes mellitus and other long-term health risks. Most of the features of PCOD associated with insulin resistance can be found under Santharpanajanya vyadhis with involvement of three Doshas and Dhathus like Rasa, Raktha and Medus. Here is a case report of 18-year-old female who presented with irregular menstruation, rapid weight gain and blackish discoloration of back of neck. Her USG findings shows bilateral polycystic pattern of ovaries. Based on clinical features and laboratory values, treatment principles adopted are Agni deepana, Ama pachana, Vatha-kaphahara and Lekhana. Varanadi kashyam and triphala choorna with takra given internally for 3 months and Udwartana was done externally for 14 days. After 3 months of treatment considerable reduction in weight and improvement in insulin resistance were noticed and her menstrual periods were normal with normal USG findings. The present case signifies the importance of Ayurvedic management in insulin resistance of PCOD to prevent forthcoming complications.

Effect of Sodhananga Achasnehapana Followed by Virechana in the Management of Rheumatoid Arthritis: A Case Report

Vishnu Sreenivas, T. K. Sujan — Fri, 03 Mar 2023 00:00:00 +0800

Rheumatoid arthritis is a chronic, progressive autoimmune arthropathy and characterized by bilateral symmetrical involvement of joints with some systemic clinical features. Treatment in allopathic medicine involves NSAIDS and steroids, which carry their own collateral burden of side effects in long term use. According to clinical features, described in Ayurveda, Vatarakta closely resembles with Rheumatoid arthritis. The study is done to find the effect of Sodhananga Achasnehapana with Guggutiktaka ghritha followed by Virechana with Nimbamrita eranda taila in Rheumatoid Arthritis. Methods: It is a simple random single case study done at Government Ayurveda College Panchakarma Hospital, Poojappura, Thiruvananthapuram. Here a case of Vatarakta (Vatakapahadikam) was treated with Sodhananga Achasnehapana with Guggutiktaka ghritha followed by Virechana with Nimbamrita eranda taila after Rukshana karma. Results: The treatment was effective in reducing the ESR, RA factor and CRP levels of the patient diagnosed with Rheumatoid arthritis. Conclusion: The case report shows that Ayurvedic treatment is potent and effective in the management of Rheumatoid arthritis. There was no adverse effect found in the treatment. Hence it can be concluded that RA can be effectively and safely treated by using the Chikitsa siddhanta mentioned in Ayurveda

Kerala Traditional Ayurvedic Practices in Children for Enhancing Immunity - A Systematic Review

Veena L, Anu M S, Delvin T Robin, Anusree Dileep — Fri, 03 Mar 2023 00:00:00 +0800

Kerala is rich in its culture for the traditional Ayurveda practices in children from the time of birth onwards. These traditional practices are mainly immune boosters and also enhance overall nourishment and development in children. Commonly used traditional Ayurveda practices are Uramarunnu Prayoga, Prakara Yoga, Abhyanga, Rasanadi churna lepana, Snana etc. for enhancing immunity and providing overall development to children. Uramarunnu is a baby care practice comprising of a group of drugs administered to the child in the form of paste in breast milk, after 28 days till 2 years of age. Prakara Yogas are immunomodulatory recipes and procedures to be adopted right from the day after delivery. Abhyanga provides nourishment, health, protection, emotional well-being and improves skin tone. All these can be used for enhancing immunity and preventing recurrent infections thereby helps in the maintenance of health and prevention of diseases. This mentions the importance of Kerala traditional Ayurvedic practices in the field of primary child health care. So, the present study aims to compile Kerala’s traditional Ayurvedic practices in children, by reviewing regional textbooks like Arogyakalpadruma, Vaidya Tarakam, Parambarya Balachikitsa etc., and also interviewing Ayurveda pediatrician through telephone.

Effect of Dasapaka Bala Taila Yonipooranam in Atrophic Vaginitis - A Case Report

Renjumol M.R, Giby Thomas, Jyothi P.K — Fri, 03 Mar 2023 00:00:00 +0800

Atrophic vaginitis is a common condition that occurs in post menopause due to the deficiency of estrogen. The condition Atrophic vaginitis is defined as atrophy of the vaginal epithelium due to decreased estrogen levels. This common menopausal condition which is often underreported and under diagnosed is caused by estrogen related changes to the vaginal epithelium and can adversely affect quality of life. Atrophic vaginitis is a common condition in postmenopausal women experience due to estrogen deficiency that causes involution of the vaginal tissue, leading to vaginal dryness, burning sensation in vagina and dyspareunia, the atrophy of the vulvovaginal structures occurs due to estrogen deficiency. Among them Sushka yoniroga can be most suitably correlated with Atrophic vaginitis. The management principle of Atrophic vaginitis includes Vathika yoniroga chikitsa, along with Sthanika chikitsa. Treatment mainly aims at Vatapittasamana, Brimhana, Balya and natural supplementation of estrogen containing drugs. Sthanika chikitsa like Yonipooranam, Pichu dharanam, etc can be done in Atrophic vaginitis. Sthanika chikitsa which is of prime importance in the management of Streeroga facilitates absorption of drugs through the vagina as the walls and adjacent tissues are highly vascular, where the medicines are administered intra vaginally. In the present case, Yonipoorana as Sthanika chikitsa as tried. A 54 year old lady was presented with complaints of burning sensation in vagina and pain during sexual intercourse. The vaginal examination was painful and the walls are found inflamed, she was diagnosed with Atrophic vaginitis. She was sent to cytological screening. The reports revealed high grade parabasal cells and low grade superficial cells. The maturation index was found 60/25/5 vaginal pH was 5.3. Pap smear was done which was negative for intraepithelial lesion or malignancy. Dasapaka Bala tailam was administered intravaginally for 7 days in 3 consecutive months. During follow up she was relieved from the symptoms like burning sensation in vagina and pain during sexual intercourse. From this case report, it shows that Yonipoorana with Dasapaka Bala tailam is effective for the management of Atrophic vaginitis.

The Role of Rasaja Bhava (Nourishing Factors) in Development of Garbha (Embryo/Foetus)

Uma B Gopal, Anagha R. Phatak, Jigisha.P S, Dharanesh S — Fri, 03 Mar 2023 00:00:00 +0800

Archaic scholars of Ayurveda lay great emphasize on intake of Ahara (food) as best source for nourishment and has a prime role in growth and development of foetus during pregnancy. In order to achieve a healthy progeny, Ayurveda classics have elucidated wholesome regimen to be followed by the parents before and after conception. There are specific procreating factors which help for the growth of embryo known as Matrujadi shad bhava (maternal and other 5 factors). Shadbhava (six factors) consist of Matruja, pitruja, Atmaja, Rasaja, Satmyaja and Satwaja in which Rasaja bhava plays an important role in providing nutrition to the foetus. The concept of Upasneha, Upasweda, Ambu, Apara and Nabhinadi are involved in nourishment of embryo/foetus at different stages of development. Acharya have drawn attention to certain food habits, to be avoided by the pregnant woman to refrain from abnormalities in the offspring. The concept of nutrition in Garbhini (Gravid Women) explained in classics has similarity with contemporary science.

Varmam Therapy for Common Shoulder Joint Pathological Conditions- A Review

Kavitha.S, Magudapathi.S, Suguna.M, Manjula.V, Dhinesh Raman.G — Fri, 03 Mar 2023 00:00:00 +0800

Varmam- a discrete medical science and a great contribution of Siddhars to Tamil Nadu. It encompases Varma martial arts, Varma therapy, internal and external medicines. Varma therapy and medicines effectively treat neuro musculoskeletal conditions which is admirable. Shoulder pain is most common orthopaedic condition. It is the third common cause of musculoskeletal consultations in primary care. Approximately 1% of adult develops new shoulder pain annually. Common pathological conditions of shoulder like rotator cuff disorders and adhesive capsulitis etc exhibits similar clinical features like pain and stiffness of shoulder joint and restricted movements. Varma therapy rearranges and regulates the “Vaasi” and consequently helps to maintain the equilibrium of trihumours (Vatham, Pitham, Kapham). This review article explicates the Varma points for the treatment of shoulder pathological conditions, the exact anatomical location of Varma points and the appropriate method of its manipulation, certainly a key to further research articles.

Ayurvedic Management of Acute Dissociative Reactions to Stressful Life Events - A Case Study

Ragitha K, Satheesh K — Fri, 03 Mar 2023 00:00:00 +0800

Mental diseases known as dissociative disorders are characterised by a sense of discontinuity and separation from one's thoughts, memories, environment, activities, and identity. People with dissociative disorders unintentionally and unhealthily flee reality, which makes it difficult for them to carry on with daily activities. Dissociative identity disorder (DID, sometimes known as multiple personality disorder), fugue, "psychogenic" or "functional" amnesia, and depersonalization disorder are examples of dissociative disorders. Other specified dissociative disorder is subcategory of dissociative disorders that describes presentations in which symptoms are typical of a dissociative disorder but do not fully match the diagnostic criteria for any of the illnesses in the diagnostic class of dissociative disorders. In Ayurveda this condition can be considered as Unmada. 34 year female patient hailing from Malappuram, Kerala, brought to Manasanthi OPD of VPSV Ayurveda College, Kottakka,l by husband and relatives complains of lack of desire to live, wants to end her life, loss of sleep, difficulty to walk and doing daily activities since 3 days. She was very much concerned about the behavioural issues and wellbeing of her elder son since 12 years. According to the informant, the patient was having increased tension, repeated talking about her elder son, making loud noises and suicidal thoughts. Also, she had an attempt to suicide. She was treated on an IP level with a combination of Ayurvedic internal medications and Panchakarma procedures. The treatment protocol includes Snehapana, Virecana, Nasya, Shirodhara, and Dhoopana. Satvavajaya methods including Yoga also administered. There were considerable relief from symptoms and HAM D score was reduced from 21 to 6.

An Analytical Review on Health Benefits of Prenatal Yoga for Mother and Foetus

Kalpana Patni, Gaurav Sinha — Fri, 03 Mar 2023 00:00:00 +0800

Pregnancy is a physiological condition in which would be mother changes both from inside as well as outside. Yoga in pregnancy can help the women to balance through these physical, mental and emotional challenges. Embracing yoga during pregnancy provides multi dimensional benefits to mother and baby. Yoga calms the mind, revitalizes the energy and prepares the woman physically and mentally for delivery. Various respiratory exercises (Pranayama) and physical postures (Asanas), performed by a pregnant woman under expert supervision, can help in harmonized relaxation and contraction of uterus, increase the strength, flexibility and endurance of muscles needed for childbirth,. They devour low energy and afford greater benefits. Also Yoga-sasanas can minimizes the complication of pregnancy, like pregnancy induced hypertension, intrauterine growth retardation and pre-term delivery. Yoga calms the mind, re-energies and prepares the mother physiologically, mentally and emotionally and for labour. Yoga is also helpful in improving sleep pattern, reduces lower back pain, nausea, headaches and shortness of breath. Simple stretching exercises encourage circulation, help fluid retention, and relieve stress. Yogic exercises can help pregnant women recover faster post-delivery. Different type of postures, mentioned in Ayurvedic and Yogic texts that can be comfortably performed in pregnancy. They consume lower energy and give better benefits. Yoga is useful for a variety of immunological, behavioral and psychosomatic conditions. Various research studies regarding the utility of yoga interventions for pregnancy shows that it is helpful in improving pregnancy and birth outcomes. Numerous clinical studies shows that yoga may produce improvements in stress levels, quality of life, aspects of interpersonal relating, autonomic nervous system functioning, and labour parameters such as comfort, pain, and duration.

A Conceptual Recapture of Stanya Kshaya and Role of Stanya-Janan Mahakashaya in its Management

Swati Goyal, Nitin Verma — Fri, 03 Mar 2023 00:00:00 +0800

Breast milk is the prime source of nourishment and immunity of the baby. Stanya Kshaya, which appears to be a fairly simple ailment but is really problematic for children's health, is one of the problems of present era. Lactation insufficiency is 30–40% prevalent in Asian and tropical nations like India. In Ayurveda certain herbs are specifically indicated for increasing breast milk and Acharya Charaka has described Stanya-janana Mahakashaya for it. Few explorations have been conducted regarding above, but no one has covered all aspects comprehensively thus this paper aim to collect and comprehensive review information available regarding concept of Stanya, its Kshaya and role of Stanya-janana Mahakashaya in its management. Methodology: This review is in a narrative format and done from literature and publications relevant to Stanya Kshaya and role of Stanya-janana Mahakashaya. Results: Stanya has been described in detail along with opinion of various Acharyas, Stanya sampata and the reasons for Stanyakshya mentioned then finally role of Stanya-janana Mahakashaya of Acharya Charaka which includes 10 herbs as- Veerana, Shali, Shasthik, Ekshuvalika, Darbha, Kusha, Kaasha, Gundra, Ithkata, Katruna. Drugs in this Kashaya help in increasing quantity of milk. Discussion: Stanya-janana Mahakashaya has active principles which increase quantity of milk, so can be used in Stanya Kshaya and leads to healthy Stanya.

Evidence Based Study of Surasadi Gana on Respiratory Disorders: A Review

Kishan Gopal Choudhary, Himanshu Rawat, Nisha Ojha — Fri, 03 Mar 2023 00:00:00 +0800

Introduction: Collection of medicinal herbs having similar effect are collectively known as Gana (group) in Samhita and Vargas (category) in Nighantu. Surasadi Gana is included in 37 of such groups mentioned in Sushruta Samhita, with 21 Herbs completing the group. This article is made in a view to review the importance and utility of few herbs included in Surasadi Gana indicated for the management of respiratory disorders.

Material and Methods: The literature regarding the drugs mentioned in the group, collected from different Ayurveda classics. Research papers are compiled from published sources and discussed in light of therapeutic effects.

Observation and Result: Maximum of the herbs in this group are having properties as Katu rasa (pungent) and Ushna veerya (hot potency). Such herbs are predominantly advised in Kapha (phlegm humour) dominant diseases, viz. Kasa (cough), Shwasa (asthma), Pratishyaya (common cold), Kushtha (skin disorders), Krimi (worm infestation) and Vrana (wound).

Conclusion: The herbs, despite having several Ayurvedic indications, the respiratory tract is the focus of the specific activity.

A Conceptual Study on Buddhi, Dhee, Dhriti, Smriti, Smritikaaranas and Medha in Comparison to Jean Piaget’s Cognitive Development Factors

Ashigha S, Prathviraj Puranik, Kavya — Fri, 03 Mar 2023 00:00:00 +0800

Building intricate scenarios and sharing these ideas with others, A full-fledged language capacity, as well as reasoning and planning skills are among the many cognitive abilities that distinguish man from other living beings. One of the tools of cognition and perception used to establish the precise qualities of an object according to Ayurveda is Buddhi (intellect). Perception occurs when the Indriyas (cognitive organs) perceives their objects along with Manas (mind), which subsequently analyze and forwards those to Buddhi producing knowledge. Dhee, Dhriti, Smriti are the components of Buddhi which aids for this and Medha is a type of intellect having the power to retain this knowledge. As per modern, cognition is the mental action or process that involves thought experiences, and the senses to acquire knowledge and understanding. The cognitive development is established through schema, assimilation, accommodation and equilibrium according to Jean Piaget’s Cognitive Development Theory. Buddhi, Dhee, Dhriti, Smriti, Smritikaarana, Medha can be correlated to these factors. Although the components of cognitive development theory were articulated for a developing kid, Ayurveda views these concepts as that which may be implied at any stage of life. One has to pass through each of these stages to achieve cognition. Hence, the present conceptual study thus focus on interpreting these Ayurvedic observations on the basis of modern theory of cognitive development and its factors.

Parallel Study of Medodhara Kala and Abdominal Adipose Tissue with Special Reference to Sthoulya (Obesity)

Pradnya R.Deshpande, Prasad P. Pande, Shital S. Swami — Fri, 03 Mar 2023 00:00:00 +0800

Obesity which is neuroendocrine disorder seems to be common predisposing factor for almost all non-communicable diseases. This neuroendocrine disturbance causes multiple systemic disorders and finally Ayurhasa (reduction in longevity of life) by various means. Ayurveda mentioned eight pathophysiological conditions considered as Nindya (worse conditions). Atisthool (excessive weight) is one of these conditions due to improper Aahara (dietary habits), Vihar (sedentary life style) and changed sleep pattern. Apachita meda (improperly metabolized fat) deposited in Udara (abdomen). Medodharakala according to Ayurveda and abdominal linings bear several similar characteristics related to fat and Medodhatu deposition. Deterioration of functioning of Medodhara kala leads to deposition of Apachita meda leading to Sthoulya. In obesity, abdominal wall, space between organs stores much amount of adipose tissue (site of Meda deposition). So this article reveals with parallel study of Medodhara kala and abdominal adipose tissue to find out similarity.

Ayurvedic Management of Primary Infertility Associated with PCOS - A Case Report

Vijila Vimal, Dei Laxmipriya — Wed, 08 Mar 2023 23:09:40 +0800

Poly cystic ovarian syndrome is a condition characterised by a wide range of signs and symptoms including menstrual irregularities, obesity, acne, hirsutism and is causing adverse effects on metabolic and endocrinal system. Exact etiology and pathophysiology is still unclear but it’s having a strong familial predisposition. This is a case report on an anovulatory infertility caused by PCOS. A 27-year-old female patient presented to the Streeroga OPD at ITRA On December 29, 2020, complaining of infertility, irregular and delayed menstruation, and weight gain over the past three years. She has been taking allopathic medicine for the same for the last two years. During her initial opd visit, she received a thorough medical history as well as all relevant clinical, physical, and laboratory tests. Bulky ovaries with polycystic morphology were discovered on sonography. Anovulatory factor infertility owing to PCOS was determined based on clinical symptoms and sonography. Pathadi choorna and Arogyavardhini rasa were chosen as medications and Samana oushadha was chosen as the line of management. The patient was counselled on lifestyle changes, the need of exercise, and correction of food habits. Patient was under medication for a period of 5 months. Patient got conceived after that and on 8^th February 2022 she gave birth to a healthy male baby per vaginally with a baby weight of 3.2 kg.