International Journal of Ayurveda and Pharma Research

An Ayurvedic Approach in the Management of Hirayama Disease

Anjana Ashok, Sunitha P. V — Fri, 10 Jan 2025 00:00:00 +0800

Hirayama disease is a self limiting condition affecting the motor component of distal upper limbs without any sensory impairment. It mainly affects young males of Southeast Asia with an increased prevalence in India and Japan. Clinical findings and Diagnosis: A 32 year old male patient approached the OPD with a known case of Hirayama disease for the past 5 years. By analyzing the condition and Dosha involved Ayurvedic treatment, both internal medication and external treatments were developed. Outcome: After a course of 28 days treatment divided into 9 and 19 days with a gap of 1 week, the patient showed significant improvement in the clinical signs and symptoms. Conclusion: Hirayama disease can be correlated to Vatavyadhi spectrum disorders like Bahusosha (a Vataja nanatmaja vyadhi). The main aim of treatment is to relieve the vitiated Vata and nourish the depleted Mamsa dhatu.

Arishta Lakshanas - A Retrospective Pilot Study Among Nurses Working In Critical Care

Basna T, Vinod DS — Fri, 10 Jan 2025 00:00:00 +0800

Life according to Ayurveda is considered as the Samyoga (combination) of Sarira (body), Indriya (sense organs), Satwa (mind) and Atma (soul). Among them Indriya refers to Arishta according to Charaka. Indriya Sthana states the relevance and importance of knowing Aristhta lakshanas before going to treatment. Arishta means, it is the state in which it has transcended all the remedial measures and widespread all over the body by the aggravation of Tridoshas. It is important in prognostication process, to prognosticate remaining survival time, in proper clinical decision making, to analyze the role and potential of Arishta Lakshanas in contemporary clinical prognostication, it helps to decide which patient to treat and which not to treat, whom to give palliative treatment and whom to give intervention treatment and helps to approach death with understanding and ease. Objective: To document perceptions, observations and experiences of nurses working in critical care on manifestation of Arishta Lakshanas in dying patients. Method: Survey study (77 nurses from different hospitals in state, national and international level was contacted and an online survey via Google forms was conducted). Results: Some of the changes in the parameters have been observed by the nurses in dying patients. Conclusion: Without Arishta Lakshanas no death occurs. So here an effort has been made to document the Arishta Lakshanas based upon some factors among the forty-eight examination factors of Aayu or Arishta stated in Indriya Sthana.

Add on Effect of Sthanika Chikitsa in Second Degree Uterine Prolapse along with Standard Conservative Management, Pelvic Floor Exercise

Giby Thomas, Thanooja Nayanar — Sun, 19 Jan 2025 10:47:23 +0800

Uterine prolapse is a type of pelvic organ prolapse where the supporting pelvic structures of the uterus weakens and result in the descent of the uterus from its normal position. This condition may arise from the gradual failure of the supporting and suspensory structures of the uterus and vaginal wall over time. Most important conservative management involves pelvic floor exercises. When conservative management fails, surgery is the only treatment option. Yonirogas which show features of pelvic organ prolapse are Prasramsini, Andini, Phalini, Mahayoni and Vatiki. Among them, Prasramsini can be most suitably correlated with 1^st and 2^nd degree uterine prolapse^[1]. The management principle of pelvic organ prolapse includes Vathika yoni roga chikitsa along with Sthanika chikitsa. Treatment mainly aims at Vathasamana, Brimhana, Sandhana, Balya and strengthening of pelvic floor musculature. This case report explores the add-on effect of Sthanika chikitsa particularly Yoni abhyanga, Yoni pichu dharana and Matra vasti with Dhanwantharam thailam and Avagaha with Dasamoola kwatha in second degree uterine prolapse with standard conservative management, pelvic floor exercise. Symptomatic relief and functional improvements were observed after 3 months of combined therapy, suggesting the additive benefits of integrating Sthanika chikitsa into standard conservative management.

Establishing Ashtanga Hridaya as the Pratisamskrita Version of Brihatrayi: A Panchavayava Vakya Analysis

Anjana Gangadharan M, MV Vinod Kumar — Fri, 10 Jan 2025 00:00:00 +0800

The relentless pursuit of knowledge and continuous learning is essential to keep any field of science relevant and applicable to the needs of society. The same is applicable to Ayurveda. In Ayurveda, Caraka Samhita recognized the importance of Pratisamskarana as a tool for updating earlier literature. Pratisamskarana includes the elaboration of portions those are brief and unclear, summarisation of those which are elaborate, thus making a new version of the original. This strong tradition of Pratisamskarana was already prevalent during the Samhita-kala. Ashtanga Hridaya, the third major treatise on Ayurveda, acknowledges that it has collected and presented the essence of knowledge from earlier textbooks. In order to establish “Ashtanga Hridaya is the Pratisamskrita version of Brihatrayi”, the technique of Panchavaya vakya was employed to establish a statement. Panchavaya vakya as described in the Nyaya system and included in the 44 Vadamarga by Acarya Caraka contains five components -Pratijna, Hetu, Udhaharana, Upanaya, Nigamana. A literary study has been done to understand Pratisamskarana, and to compare the detailed and concise portion of Caraka Samhita and Susruta Samhita with the later text in Samhita kala, Ashtanga Hridaya. This attempt aims to establish that the Ashtanga Hridaya is an updated version of Brihatrayi, based on the analysis through Panchavaya vakya.

Ayurvedic Management of Hypothyroidism Through Vamana

Sreelal A S, Manju P S — Fri, 10 Jan 2025 00:00:00 +0800

Hypothyroidism, a condition characterized by an underactive thyroid gland, results in the insufficient production of thyroid hormones, leading to a slowdown in metabolic processes. This endocrine disorder is prevalent worldwide, affecting millions of individuals, particularly women. It is characterized by insufficient production of thyroid hormones, is a prevalent endocrine disorder that can lead to a myriad of health complications including fatigue, weight gain, depression, and cardiovascular issues. Diagnosis is primarily based on clinical symptoms and confirmed through laboratory tests measuring serum levels of Thyroid Stimulating Hormone (TSH) and free thyroxine (T4). Conventional treatment primarily involves hormone replacement therapy, which aims to restore normal hormone levels but does not address underlying causes or provide holistic healing. Vamana, as an Ayurvedic therapeutic procedure, is proposed as an alternative or complementary treatment for hypothyroidism. This process involves induced therapeutic vomiting to eliminate toxins (Ama) and balance the body's Doshas, particularly Kapha, which is often implicated in hypothyroidism. It also helps in the management of Rasavaha, Medovaha dushti and Bahudoshavastha lakshana. Hence in this case study we can see the effect of Vamana in TSH level and marked improvement in signs and symptoms which were measured before and after the treatment.

Systematic Review of Amavata w.s.r. to Rheumatoid Arthritis

Alisha Usmani, Piyush Gupta, Atul Kumar Agrawal, Ketan Mahajan — Fri, 10 Jan 2025 00:00:00 +0800

The main aim of Ayurveda is to maintain the health of the healthy person and to cure the disease of a diseased person. In the present era Amavata is the most prevalent and debilitating form of joint illness. Amavata term is derived from two words Ama and Vata, the condition which is caused by accumulation of Ama and Vata and it is a Madhyam Roga Marga Vyadhi. Due to Hetu Sevan when circulating Ama combines with vitiated Vata and get accumulated in Sandhis. Vata acts as an Avaraka and blocks Shrotas the pathogenesis of Amavata occurs. Amavata is a disease of Rasvaha Shrotas and the clinical presentation of Amavata like pain, swelling, stiffness, fever, redness, general debility, fatigue, closely mimics with the special variety of rheumatological disorders called rheumatoid arthritis. In Vedic Kala, only Atharva Veda mention the Sandhi related Vyadhis. In various Samhitas the fragmented description of Amavata is available. But only in Madhav Nidan separate chapter is mentioned about the etiology, clinical features, types and prognosis of Amavata. In the disease of Amavata due to Agnimandhya, Amotpatti, and Sadhivikriti occurs. The therapy which normalizes Agni, metabolizes Ama, and regulates Vata and maintains healthy Sandhi and Sandhistha shleshma will be the supreme one of this disease. As per Ayurveda, the line of treatment for the management of Amavata as described by Chakradatta are Langhana, Swedana, Tikta, Deepaniya, Katu drugs and other Panchakarma procedures like Virechana, Snehpana, Basti Karma, Saindhvadi Anuvasana Basti etc. So, the present study deals with the systematic review of Amavata, from all the classics of Ayurveda, and its management.

Effect of Lasunerandadi Kashaya in Oligomenorrhea Associated with Polycystic Ovarian Syndrome

Shahina Mole S, Anjitha B S — Fri, 10 Jan 2025 00:00:00 +0800

Polycystic ovarian syndrome (PCOS) is a heterogeneous, multisystem endocrinopathy in women of reproductive age that is characterized by chronic anovulation, resulting in infertility, irregular bleeding, obesity, and hirsutism. The prevalence of PCOS in reproductive-age women was mentioned as 20% to 30%, with 90% of affected women presenting with oligomenorrhea, 30% with amenorrhea, and 50% being obese. In Ayurveda, there is no direct correlation with Polycystic ovarian syndrome. Kapha vata avarana causing Artavanasha, which is explained as Nashtartava by Susrutha, can be considered in this particular disease. This case series contains 4 cases of oligomenorrhea associated with PCOS with BMI > 25 Kg/m² attended the OPD of Prasuti evam Striroga, Government Ayurveda College, Thiruvananthapuram. Effect of Lasunerandadi Kashaya was analysed and was found effective in oligomenorrhea associated with PCOS.

An Ayurvedic Approach in the Management of Female Infertility Caused due to Uterine Factor

Priyanka Kamble, Swathi C, L.V. Rathnakar — Fri, 10 Jan 2025 00:00:00 +0800

Infertility due to multiple factors is one of the predominant health issues faced by married couples nowadays. It is common in 10-15% of couples. Both male and female factors contribute to the infertility. Ayurvedic approach is helpful in these steps to improve the overall health of the women. Shodhana therapy like Virechana and Basti work as the Garbha Adhana Shodhana procedure in the female and brings the Doshas in the Sama Avastha which will eventually help in conception. Materials and Methods: The case presented in the study is of a married couple who have been anxious to conceive for 9 years. She was started on Ayurvedic Shamana therapy to regularize her menstrual cycles last year. Later, she was admitted to the IPD for the Virechana and Yoga Basti procedure. Results: During the treatment, the patient regained regular menstrual cycles. She also has initiation of regular ovulation and has improvement in endometrial proliferation and layering. Conclusion: It is a case of infertility that includes multiple female factors such as uterine fibroids, uterine synechiae, irregular menstrual cycles, anovulation, and low AMH levels. Based on the parameters of Ayurvedic science this case was diagnosed as Vandhyatwa (infertility) The treatment included Shamana therapy to suppress the vitiated Vata and Kapha Dosha, and Shodhana to improve the Stroto Shuddhi for ovulation indication and adequate formation of endometrial layering. Hence, Ayurveda treatment can be used in patients with infertility with better outcomes.

Role of Shleshmatakadhya Agad in the Management of Dushi Visha

Fri, 10 Jan 2025 00:00:00 +0800

Ayurveda is an ancient science that aims to maintain the good health and to cure the diseases and pathological conditions of human beings. Agad tantra is a branch of Ayurveda that deals with the Visha (poison), its associated symptoms along with its Chikitsa (management). In Agad tantra, concept of Viruddhahara (incompatible food/diet), Gara Visha (concocted poison) and Dushi Visha (denatured/latent poison) has been explained in detail that contributes to the leading reasons for the occurrence of toxicity related disorders or disease. Most of the diseases are caused due to unconventional etiology for which Agad tantra comes into focus. To combat the poisonous effect, various Agad Yogas are mentioned in Visha Chikitsa grantha to counteract all types of poisons (Sthawara, Jangama, Kritima visha, Gara visha, Dushi visha). Shleshmatakadhya Agad is one of the Yoga mentioned in Yogaratanakar as a Sarva- vishanashanam under Visha Chikitsa. Shleshmatakadhya agad contains Shleshmatak, Apamarga, Guduchi, Nripdruma, Kantakari and Brihati. This article highlights the role of Shleshmatakadya agad, an antitoxic formulation to conquer diseases due to unconventional etiology in current scenario.

The Application of Nasya in Pakshaghata

Sariga S, Ratheesh P, Vinitha C, Rahul Ravi P, Ananthalekshmi R — Fri, 10 Jan 2025 00:00:00 +0800

Pakshaghata is among the eighty Nanatmaja vikara explained by Acharya Charaka in Sutrasthana, Maharoga adhyaya. The major Lakshanas include Chesta nivruthi of Ardhanga, rujam and Vaksthambha. Even though it is generally mentioned under Kevala vata vyadhi, Acharya Susrutha has mentioned its subtypes as Kaphanubandhi and Pittanubandhi. According to Ayurveda, the disease affects the Madhyama roga marga and causes the Soshana of Sira and Snayu. From this, it can be inferred that Raktha dhathu is also involved in the pathogenesis of the disease. Specific Nidanas of Pakshaghata have not been mentioned, therefore general factors causing Vata prakopa can be considered. Some consider Ardhita as synonym of Pakshaghata, then Ardhita nidana becomes applicable. Ultimately it occurs due to Dhathu kshaya or Margavarana. In Pakshaghata margavarodha of Vyana vayu occurs due to Nidanas causing impairment in Dhathu poshana, finally leading to Dhathu kshaya. In modern medicine this condition may be correlated to hemiplegia that occurs after a cerebro vascular accident. It is considered as a disease of difficult prognosis if not managed immediately. But in Ayurveda, the treatment concept is different and has received wide acceptance. The line of treatment according to Acharya Charaka is Snehana, Swedana and Virechana. This highlights the importance of Panchakarma chikitsa in Ayurveda. Even though Virechana is the Shodana procedure mentioned in Chikitsa sidhanta, all the Shamana and Shodana therapies mentioned in Ayurveda are found to be effective in managing Pakshaghata. This article aims to review the mode of action of Nasya in Pakshaghata. Nasya is one among the Panchakarma and is indicated for Urdwa jatrugata vikaras. Nasa being the Siraso dwaram, medicine instilled through nostrils can cure the diseases of the head by spreading through Sringataka marma. This is considered as the concept behind the action of Nasya.

A Conceptual Study on Anti-Poisonous Effect of Neeli Patradi Leham

Indu. V. A, Shiji. R. S — Fri, 10 Jan 2025 00:00:00 +0800

Agada Tantra, as one of the eight principal branches of Ayurveda, focuses specifically on the management of Visha diseases, which encompass illnesses caused by toxins or poisons. Agada Tantra's role within Ayurveda is pivotal in addressing Visha diseases through a comprehensive approach that includes identification, prevention, diagnosis, and treatment. By blending ancient knowledge with modern insights, Agada Tantra continues to make significant contributions to the understanding and management of toxins and their impact on human health. Kerala indeed has a rich tradition in toxicology, rooted deeply in its ancient texts and practices within Ayurveda. The "Visha Vaidya Jyotsanika" is a renowned Malayalam text that focuses on Visha Chikitsa (toxicology) and offers valuable insights into various formulations and clinical practices. Neelipatradi leham is a formulation serves as a potent remedy mentioned in this text for counter acting poisons. This study emphasize on the components, preparation technique, indications, and efficacy of the formulation.

Exploration of the Pharmacological Properties, Actions and Therapeutic Potential of Amritotharam Kwatha

Anu Sreedevi, Sethu R — Fri, 10 Jan 2025 00:00:00 +0800

Nature and its elements are closely attached to human existence as the five elements that makes up the human body reflects the five elements that makes up all the matter that we see around us which has been one prime reason that herbal medicine has existed from time immemorial. Its prime principle is that deficiencies and defects in a five elemental body could always be repaired by drugs filled with abundance of same elements. Humans are also prone to a vast variety of diseases and health disorders as they tend to deviate from the things that keep the functional elements of the body in equilibirum and this leads to the onset of diseases. Such cases required medicines that can remove Dosha imbalance, promote and maintain the digestive fire, and at the same time act as a preventive measure for possible secondary diseases as well providing an immunomodulatory effect as well. Amritotharam kwatha is a renowned, widely accepted and therapeutically used Ayurvedic formulation by all Ayurvedic physicians throughout the country. The formulation is mentioned specifically in the text Sahasrayogam as well as other texts like Chikitsamanjari, Yogamritam in the contexts of Jwara chikitsa to combat Jwara of all types and its associated health issues. This article is intended to explore the pharmacological properties, actions and the therapeutic potential of Amritotharam Kwatha.

Unlocking the Therapeutic Essence of Hingwadi Agada: An Ayurvedic Hertiage In Healing Practices

Vidya.S.Kukanur, Ravikrishna.S, Shubha.P.U, Chaithra Hebbar — Fri, 10 Jan 2025 00:00:00 +0800

Agadatantra is an essential part of Ashtanga Ayurveda, dealing with the clinical aspects of poisoning, including its identification and therapeutic interventions. Vrischika visha is one of the critical clinical conditions requiring emergency care. Various antidotal formulations in Ayurveda known as Agada Yoga’s (anti-toxic formulations) are useful in Vrischika Visha Chikitsa. Hingwadi Agada is one of the Agada Yoga’s mentioned by Acharya Vagbhatta in Ashtanga Hridaya. Aim and objectives: Based on the function of Hingwadi Agada ingredients are described in various classical texts, this review and debate will focus on Vrischika Visha Damsha. Materials and Method: Several classical texts were referred, namely Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya, Ashtanga Sangraha, various Nigantus and textbooks like the Dravyaguna Vigyana and Peer Review articles. Observations and Results: According to Acharya Vagbhatta, Hingwadi Agada includes two main ingredients along with a single processing medium all of which possess properties such as Deepana (appetite-stimulating), Pachana (digestive enhancing), Shulahara (analgesic). Sothahara (anti-inflammatory), Sonithsthapana (blood stabilizing), Vatanuloma (regulating the Vata Dosha etc. Conclusion: According to Acharya Vagbhatta's Vrischika Damsha Chikitsa, Hingwadi Agada holds potential as an effective antidote and deserves to be explored through clinical and experimental trials for treating Vrischika Visha.

Role of Asatmyendriyartha Samyoga in Causation of Lifestyle Disorders

Sahore Shikha, A Arhanth Kumar, K Vidyalakshmi — Fri, 10 Jan 2025 00:00:00 +0800

The rise of lifestyle disorders such as diabetes, obesity, hypertension, and stress-related conditions is attributed to unhealthy habits and environmental stressors. Ayurveda identifies their root causes as imbalances in the interaction between the body, mind, and environment, particularly through Asatmyendriyartha Samyoga (improper sensory engagement). This occurs when sensory organs (Indriya) and their objects (Artha) are used excessively, insufficiently, or inappropriately, leading to physical, mental, and emotional disharmony, toxin buildup, and chronic diseases. The Charaka Samhita highlights three causative factors: Kaala (time), Buddhi (intellect), and Indriyartha (sensory interactions), emphasizing Asatmyendriyartha Samyoga's critical role. Modern triggers, such as excessive screen time, unhealthy diets, and noise pollution, exacerbate this misalignment, resulting in stress, weakened immunity, and lifestyle-related diseases. Prajnaparadha (intellectual errors) and Manas (mind) further aggravate these conditions by disrupting cognitive and emotional balance, contributing to psychosomatic disorders like anxiety and depression. Preventive strategies in Ayurveda include Dinacharya (daily routines), Ritucharya (seasonal regimens), Sadvritta (ethical conduct), Achara Rasayana (rejuvenative practices), and Nidana Parivarjana (elimination of causes). These promote balanced sensory engagement, resilience, and holistic well-being. Ayurveda emphasizes mindful living and conscious sensory alignment to prevent disease and enhance longevity. By restoring harmony in sensory interactions, individuals can achieve sustainable health, resilience, and a life aligned with Ayurvedic principles of well-being.

Dipana, Pachana, Agni, and Metabolism: A Synergistic Perspective on Health

Mohammed. Asif, Siva Sahithi — Fri, 10 Jan 2025 00:00:00 +0800

In Ayurveda, the concepts of Dipana (enhancing digestive fire) and Pachana (burning or metabolizing toxins) play vital roles in maintaining health and vitality. These principles resonate deeply with modern scientific understandings of metabolism, the biochemical engine that powers our body. A closer look reveals intriguing correlations between Dipana and exercise, Pachana and fasting, and their mutual connection through the concept of Agni, the Ayurvedic term for digestive and metabolic fire. This article dwells into detailed analysis of these aspects along with their actions on the body.

An Ayurvedic Literary Review on Kashtartava w.s.r. to Primary Dysmenorrhea

Sonika Pal, K. Bharathi, Chandra Prakash — Fri, 10 Jan 2025 00:00:00 +0800

Kashtartava, commonly identified as primary dysmenorrhea in modern medicine, is a prevalent gynecological condition characterized by painful menstruation without any discernible underlying pelvic pathology. This condition significantly impacts the quality of life of affected individuals, warranting effective diagnostic and management strategies. This review aims to bridge traditional Ayurvedic insights with contemporary medical perspectives to provide a holistic understanding of Kashtartava.

In Ayurveda, Kashtartava is attributed to the vitiation of Vata dosha, particularly Apana Vata, which governs the reproductive system's functioning. Classical texts emphasize the role of dietary habits, lifestyle, and mental well-being in the pathogenesis of this condition, offering detailed descriptions of its symptoms, etiological factors, and therapeutic interventions. The article correlates these Ayurvedic principles with modern pathophysiological findings, including hormonal imbalances, uterine contractions, and prostaglandin overproduction, which are implicated in primary dysmenorrhea.

The review highlights Ayurvedic diagnostic approaches, including pulse diagnosis and the assessment of Dosha imbalances, alongside contemporary diagnostic tools such as ultrasound and hormonal assays. Management strategies are explored comprehensively, focusing on Ayurvedic treatments like Panchakarma, herbal formulations, and lifestyle modifications.

Krishna's Diabic Care: An Evidence-Based Review of Ingredients for Diabetes Control

Shrawan Daga, Pradeep Shrivastava, Divya Sharma — Fri, 10 Jan 2025 00:00:00 +0800

Krishna’s Diabic Care is an Ayurvedic formulation aimed at managing diabetes by combining traditional herbal remedies with holistic approaches. This review explores the potential benefits, safety profile, challenges, and future directions of this product in the context of diabetes management. Krishna’s Diabic Care utilizes a blend of herbs traditionally used in Ayurvedic medicine, such as Trigonella foenum-graecum, Syzygium cumini, Momordica charantia, Gymnema sylvestre, Azadirachta indica, Aegle marmelos, Ocimum sanctum, Pterocarpus marsupium, Phyllanthus emblica, Tinospora cordifolia, and Picrorhiza kurroa, known for their roles in supporting blood sugar regulation, improving insulin sensitivity, and reducing complications related to diabetes. However, scientific validation through clinical trials is needed to confirm the long-term efficacy and safety of Krishna’s Diabic Care. While the product demonstrates promise, its integration into mainstream diabetes management is hindered by the lack of robust clinical evidence, potential variations in formulation quality, and regulatory challenges. Collaborations between Ayurvedic practitioners and modern researchers could further bridge traditional knowledge with contemporary medical practices, facilitating broader acceptance of Ayurveda in managing chronic conditions like diabetes. The review concludes that Krishna’s Diabic Care holds potential as part of a holistic diabetes management strategy, with the need for rigorous clinical validation to enhance its credibility and integration into global healthcare systems.

Phytochemistry and Pharmacology of Helicteres Isora Linn. (Marodphali): Ayurvedic Insights and Medicinal Overview

Kharwar Beauty, Siddiqui Talib, Ehsan Mohd — Fri, 10 Jan 2025 00:00:00 +0800

It is a small, sub-deciduous tree or shrub that is commonly cultivated. People have used it for medicinal purposes since antiquity, in organized (Ayurveda, Unani & Siddha) and unorganized (folk, native and tribal) forms. Marodphali is a well-known Ayurvedic remedy for curing various diseases and has several pharmacological effects. Marodphali, scientifically classified as Helicteres isora Linn., is a member of the Sterculiaceae family. It is also referred to as Avartani. On the preliminary phytochemical screening, it is reported that the plant of Marodphali consist of several bioactive compounds like alkaloids, steroids, phenolic compounds, carbohydrates, proteins, saponins and flavonoids, which proclaim various important Pharmacological effects encompass antioxidant properties, lipid-lowering (hypolipidemic) effects, antibacterial and antiplasmin actions, cardiotonic benefits, anti-oxidative and anti-peroxidative potential, neuroprotective antioxidative capacity, anticancer effects, analgesic (anti-nociceptive) properties, liver-protective (hepatoprotective) effects, anti-diarrheal benefits, and wormicidal activity. Marodphali's multifaceted therapeutic profile positions it as a promising natural remedy for a range of pathological conditions, highlighting its potential for broader clinical applications pending further research into its molecular mechanisms of action.