International Journal of Ayurveda and Pharma Research https://ijapr.in/index.php/ijapr <div align="justify"> <p class="para1"><strong>International Journal of Ayurveda and Pharma Research (IJAPR)</strong>&nbsp;is an international peer reviewed Monthly open access Online and Print journal. The aim of the journal is to increase the impact of research in both academic and industry, with strong emphasis on quality and originality. The journal promotes to publish the articles in the field of&nbsp;<strong>Ayurveda, Siddha, Yoga, Naturopathy, Unani, Homeopathy and Allopathy</strong>&nbsp;systems of medicine and Pharmaceutical Sciences. Researchers may submit (1). Original Research Articles (2). Review articles (3). Book Reviews (4). Short Communications/ Research Letter (5). Case Report (6). Letter to the Editor/Correspondence.</p> </div> en-US editor@ijapr.in (Dr B Srinivasulu M.D (Ayu.)) Mon, 10 Jun 2024 00:00:00 +0800 OJS 3.1.2.1 http://blogs.law.harvard.edu/tech/rss 60 Evaluation of Antimicrobial Efficacy of 5% Myristica Fragrans Mouthwash in Gingivitis Subjects - A Clinico Microbiological Study https://ijapr.in/index.php/ijapr/article/view/3201 <p>Gingivitis is the inflammation or infection of gingiva that support the teeth. The prevailing belief regarding the cause for gingivitis is the toxins produced by the bacteria in the mouth, particularly the bacteria that causes the formation of plaque. <em>Myristica fragrans</em> commonly known as nutmeg possesses anti-carcinogenic, anti-inflammatory activities, antioxidant effect, anti-diabetic, and antibacterial properties. The seeds of nutmeg have the ability to inhibit the growth of Gram Negative and Positive bacteria. <strong>Objective: </strong>1. To evaluate clinical parameters at baseline and 21 days post scaling after the use of <em>Myristica fragrans</em> mouthwash. 2. To evaluate the colony count of <em>Porphyromonas gingivalis</em> in plaque samples at baseline and 21 days after the use of <em>Myristica fragrans</em> mouthwash.<strong> Methodology:</strong> A total of 40 gingivitis subjects were selected and divided randomly into Group A and B. Group A, Non-surgical periodontal therapy followed by <em>Myristica fragrans</em> mouthwash (20) and Group B, Non-surgical periodontal therapy alone (20). The supragingival plaque samples were collected at baseline and 21 days after non surgical periodontal therapy.<strong> Results: </strong>Significant reduction in clinical parameters and colony count of <em>Porphyromonas gingivalis</em> after the use of 5% <em>Myristica fragrans</em> mouthwash.</p> Nagaraj B Kalburgi, Arati C Koregol, Anjaly Roy, Uzma Parveen Sultana Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3201 Mon, 10 Jun 2024 00:00:00 +0800 Amazonite (A Microcline Feldspar) - An Anti-Cancerous Geo-Biotechnological Approach for H460: Human Lung Cancer with Validation via Ros Anti-Oxidant Analysis https://ijapr.in/index.php/ijapr/article/view/3245 <p>The research delves into the medicinal properties of amazonite, with a particular focus on its potential application in nanomedicine for combating lung cancer. Employing the MTT Assay, the authors observed amazonite's impact on H460 lung cancer cells, revealing its cytotoxic effects and thereby suggesting its promise as an anti-cancer agent. Moreover, through ROS antioxidant analysis, the study unveiled amazonite's ability to regulate reactive oxygen species levels, indicating its potential in mitigating oxidative stress-induced damage, a hallmark of cancer progression. FTIR spectroscopy emerged as a crucial tool in the research, offering insights into amazonite's molecular composition and its possible interactions with biological molecules. Of paramount importance is the toxicity analysis conducted in the study, which revealed amazonite's low toxicity profile. This aspect is particularly significant as it underscores the safety of amazonite for potential therapeutic applications, including in conjunction with treatments like radiotherapy. The assurance of low toxicity is pivotal in ensuring the viability of amazonite as a candidate for clinical use, instilling confidence in its safety profile and minimizing adverse effects on patients. Overall, the findings of the research underscore amazonite's potential as a safe and effective nanomedicine for the treatment of lung cancer. The observed cytotoxic effects on cancer cells, coupled with its ability to modulate reactive oxygen species levels and low toxicity profile, position amazonite as a promising candidate for further exploration in the realm of cancer therapy. However, the study also highlights the need for continued research to fully elucidate the underlying mechanisms of amazonite's action and to explore its potential clinical applications comprehensively.</p> Yamini Malhotra, Singara Subramanian, Ishfaq Mohiuddin, Venkatesan selvaraj, Ajin Bejino A, Bobby Jones A Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3245 Mon, 10 Jun 2024 00:00:00 +0800 The Efficacy of Vibhithaki Ksharasutra in the Management of Bhagandhara (Fistula In Ano) A Controlled Clinical Trail https://ijapr.in/index.php/ijapr/article/view/3251 <p><em>Bhagandara</em> (Fistula-In-Ano) is one of the <em>Astamahagadha</em> disease mentioned in <em>Susrutha</em> <em>Samhitha</em>, which is difficult to cure. Fistula-In-Ano is an abnormal communication between two epithelial-lined surfaces in the anorectal region. Various operative procedures (fistulectomy, etc.) often lead to complication ns like recurrence, incontinence of the anal sphincter, and other infections resulting from surgery. The <em>Kshara Sutra</em> is a parasurgical procedure that is found to be more effective in the management of fistulas in ano. The <em>Apamarga Ksharasutra</em> is widely used and is made up of <em>Apamarga Kshara, Snuhi Kshira </em>and<em> Haridra</em>. The preparation process for <em>Apamarga Kshara</em> can be difficult and time-consuming. If we turn to the classics, we find the reference to <em>Vibhithaki</em>, mentioned under <em>Kshara Dravys</em>, which are used to prepare <em>Ksharasutra</em>. <em>Vibhitaki</em> is cost-effective and easily available as it is a big tree. The properties of <em>Vibhitaki</em> are favourable to <em>Kshara</em> qualities The present clinical study deals with the efficacy of <em>Vibhitaki</em> and <em>Apamarga Kshara Sutras</em> in the management of <em>Bhagandara</em>.</p> M.Prabath, K.V.Vijaya Bhaskara Reddy, Renu Dixit Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3251 Mon, 10 Jun 2024 00:00:00 +0800 An Open Randomised Clinical Study to Evaluate the Combined Effect of Krishna Tila Kashayam and Shatapuspa Choornam in PCOS https://ijapr.in/index.php/ijapr/article/view/3256 <p>PCOS has ovarian dysfunction along with hyperandrogenism and polycystic ovarian morphology. PCOS is a condition where involvement of <em>Kapha dosha</em> is present along with <em>Vata</em> <em>dosha</em> along with <em>Rasa Dhatu, Medo dhatu</em> and <em>Arthava- </em>the<em> Upadhatu </em>of<em> Rasa</em> is affected. Because of having the properties of <em>Ushna virya, Kashaya Tiktha rasa, Arthava janana</em> properties, <em>Krishna Tila Kashayam</em> and <em>Shatapuspa choornam</em> has been mentioned for the treatment of <em>Arthava kshaya</em> (anovulation and oligomenorrhea) in PCOS. The treatment is fully focused on <em>Vata Kapha hara chikitsa</em> and <em>Arthava vardhaka</em>. The drugs selected for the present study can be easily prepared and administered, cost effective. In this study, <em>Tila kashayam</em> along with <em>Anupanam Gudam</em> and <em>Shatapuspa choornam</em> along with <em>Anupanam Madhu</em> has been given and the results have been noted. In the present study, a total of 40 patients suffering from PCOS were selected from OPD and IPD of SJSACH. The thesis is widely focused on increasing the quantity of flow in amenorrhoea or oligomenorrhea cases, to check the size of the ovarian follicle before and after treatment and to check if there is any reduction in hair growth in hirsutism patients. There was a notable change seen in mild to moderate PCOS cases regarding the interval between 2 cycles, duration of flow between 2 cycles and quantity of flow between 2 cycles. There was a notable change seen in reduction of ovarian cyst volume before and after treatment. Hirsutism, BMI and waist circumference - there was no significant changes noted during these 3-month period.</p> Gulnar Mariam.M, Swathi.C, Venkata Ratnakar.L Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3256 Mon, 10 Jun 2024 00:00:00 +0800 Management of Shwitra (Vitiligo) Through Ayurveda https://ijapr.in/index.php/ijapr/article/view/3186 <p>A condition of acquired macular depigmentation called vitiligo is linked to melanocyte degeneration, caused by the autoimmune destruction of melanocytes cells. This vitiligo can be correlated to <em>Shwitra </em>in Ayurveda because of the disease's resemblance in appearance<em>. </em>In the Ayurveda classics especially <em>Charaka Samhita,</em> <em>Shwitra</em> has been mentioned under the heading of <em>Kushta Roga Chikitsa</em>.<strong> Methodology:</strong> The present case report is of 11 years old female child, came with complaints of whitish discolored patches on the almost all over body, effectively treated with <em>Shamana</em> and <em>Shodhana</em> <em>Chikitsa</em>. <strong>Result:</strong> Patient showed encouraging result after <em>Shodhana Chikitsa</em>, where subjective criteria evaluated using scoring method and objective criteria evaluated using VASI scoring method. <strong>Discussion:</strong>&nbsp;Patient was treated with <em>Shamana</em> <em>Aushadis</em> and <em>Shodhana</em>, where white discolored patches turned to pinkish, and after that the patches turned into normal skin color. Subject was observed with 95% improvement in subjective criteria &amp; VASI scoring improved from 19.85 to 3.2. <strong>Conclusion:</strong> The present case study validated the efficacy of Ayurveda medicine in treating <em>Shwitra</em>.</p> Rani Khandelwal, Chandraprabha Sharma, Harish Kumar Singhal, Dinesh Kumar Rai Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3186 Mon, 10 Jun 2024 00:00:00 +0800 Standardization and Quality Assessment of Drakshavaleha: Insights from Three Marketed Brands https://ijapr.in/index.php/ijapr/article/view/3219 <p><em>Drakshavaleha</em>, a traditional Ayurvedic formulation, is widely used for its therapeutic benefits in treating respiratory and digestive ailments. This study aims to standardize and evaluate the quality of <em>Drakshavaleha</em> from three different marketed brands through a comprehensive assessment of their physicochemical and pharmacognostical properties, alongside an estimation of toxic heavy metals content and microbial contamination, and phytochemical profiles. <strong>Materials and Methods</strong>: Three brands of <em>Drakshavaleha</em> were meticulously assessed through a range of tests, including organoleptic analysis, physicochemical evaluations, heavy metal content analysis, microbial contamination assessments, and qualitative phytochemical screenings. Standardized protocols and methodologies from pharmacopoeias were used for all evaluations to ensure reliable and consistent results. <strong>Results and Discussion</strong>: The findings indicated notable variations in the evaluation parameters of the different brands. Physicochemical and Pharmaceutical analysis revealed disparities in pH levels and total reducing sugar levels. Heavy metal testing and microbial contamination levels were within acceptable ranges for all samples. The qualitative phytochemical screening identified differences in the concentration of key active ingredients, potentially impacting therapeutic efficacy. <strong>Conclusion</strong>: This study underscores the importance of standardization in maintaining the safety and efficacy of Ayurvedic formulations. By identifying variations in quality and safety parameters, it provides critical insights for manufacturers to improve their production processes. Ultimately, this research advocates for enhanced quality assurance practices to uphold the integrity of Ayurvedic medicine in the global market.</p> Princy Agarwal, Anju Goyal Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3219 Mon, 10 Jun 2024 00:00:00 +0800 An Alternative Approach to the Treatment of Arthritis https://ijapr.in/index.php/ijapr/article/view/3221 <p>Arthritis, also known as joint inflammation, is the swelling and tenderness of one or more joints in the body. With the main symptoms being stiffness of joints and pain, arthritis can severely affect the quality of life. It worsens with age and typically shows itself in adult ages. This case study is of a very young, 19-year-old woman, who was diagnosed with rheumatoid arthritis at the age of 18. After Ayurvedic assessment, she was recommended the use of herbal blends, oils, Ayurvedic diet, and lifestyle changes. This was done in gradual phases and lasted for about six months. The American College of Rheumatology’s Arthritis Impact Measurement Scales were used for pre and post assessment. Post Ayurvedic management, the client’s situation is greatly improved after Ayurvedic management and she still follows ayurvedic recommendations for maintenance. This case study provides positive insights and alternatives into the management of Arthritis.</p> Soumya Upadhyay Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3221 Mon, 10 Jun 2024 00:00:00 +0800 The Efficacy of Vibhithaki Ksharasutra in the Management of Nadivrana w.s.r Pilonidal Sinus https://ijapr.in/index.php/ijapr/article/view/3249 <p>Pilonidal sinus (PNS) is a chronic disorder that occurs in the space between the buttocks (natal cleft). Men are more susceptible (because they have more hair) to pilonidal sinus than women. Excision, primary closure and reconstructive flap surgery are the most commonly used surgical techniques for this disease. However, there is a high risk of recurrence or wound infection after surgery. In addition, the patient needs a longer hospital stay, and the procedure is expensive. <em>Acharya Susrutha</em> (800 BC) considered this disease under <em>Nadivrana (Shalyaja</em>) and advocated&nbsp;a minimally invasive para surgical treatment namely the <em>Kshara Sutra</em> procedure. <em>Susrutha </em>mentioned <em>Kshara dravyas</em> like <em>Apamarga, Palasha, Vasa, Vibhithaki</em>, etc used in the preparation of the <em>Ksharasutra</em>. Here we selected <em>Vibhitaki</em> to prepare <em>Kshara</em> and <em>Ksharasutra</em>. <em>Vibhithiki</em> is cost-effective as it is easily available and the properties of this plant are favourable to <em>Kshara</em> qualities. The present case study deals with the efficacy of <em>Vibhitaki Ksharasutra</em> in the management of<em> Nadivrana</em> (pilonidal sinus).</p> M. Prabath, K. V. Vijaya Bhaskara Reddy, Renu Dixit Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3249 Mon, 10 Jun 2024 00:00:00 +0800 Effect of Virechana Karma Along with Japapatryadi Tail Local Application and Amritadi Kwath Orally in the Management of Vicharchika https://ijapr.in/index.php/ijapr/article/view/3255 <p>In the present case report, a 58-year-old man consulted in the Outpatient department of Dayanand Ayurvedic College, Jalandhar. The complaint of the patient was recurrent skin rashes with redness, skin oedema, itching, flaking and discolouration in the skin. By examining the signs and symptoms, the patient was diagnosed with Eczema (<em>Vicharchika</em>), <em>Shodhana and Shaman Chikitsa </em>was given under the treatment of <em>Vicharchika<sup>[1]</sup></em>. <em>Vicharchika, </em>according to Ayurveda<em>, is a Raktapradoshaja Vyaadhi </em>with the involvement of<em> Tridoshas, </em>and it is <em>Kapha</em> in predominance<sup>[2]</sup>. The patient was given <em>Virechana Karma</em> along with the local application of <em>Japapatryadi tail</em> and <em>Amritadi kwath</em> orally for a period of 2 months. After that, the condition of the patient was assessed on the basis of signs and symptoms of <em>Vicharchika</em>, which were cured after taking the treatment. This study shows that the cases of eczema (<em>Vicharchika</em>) can be successfully managed with <em>Virechana Karma</em> followed by <em>Japapatryadi tail</em> locally and <em>Amritadi kwath</em> given orally.</p> Sharma Megha, Sood Sanjeev Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3255 Mon, 10 Jun 2024 00:00:00 +0800 Standardization of Pharmaceutical and Analytical Analysis of Chincha Kshara https://ijapr.in/index.php/ijapr/article/view/3246 <p>Acharya Susrutha has narrated <em>Kshara</em> as one of the <em>Upayantras</em>, <em>Anusastras</em>, <em>Agropaharaniya</em> and one of the <em>Upakrama</em> of <em>Vrana</em>. <em>Kshara</em> is considered superior to all surgical and para surgical measures. <em>Kṣharas</em> are more effective than other methods of treatment, because they can be used externally as <em>Pratisaraniya Kshara</em> and internally as <em>Paneeya Kshara</em>. Because of varied applications standardization of the compound formulation is the need of the present era to set standards for maintaining the quality of the products. In the present study work is done on the pharmaceutical and analytical study of <em>Chincha Kshara</em> conducted in the department of <em>Shalya Tantra</em> under the post graduate programme is being presented. Here an attempt has been made to study <em>Chincha Kshara</em> Analytically and to develop fingerprints by organoleptic tests, physico-chemical parameters and Inductively Coupled Plasma - Optical Emission Spectrometry (ICP-OES).</p> Patam Mounika Yadav, K.V.Vijaya Bhaskara Reddy, Renu Dixit Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3246 Mon, 10 Jun 2024 00:00:00 +0800 Pharmaceutical Standardization of Sharpunkha Kshar (Lavana): A Miraculous Hepatoprotective Drug https://ijapr.in/index.php/ijapr/article/view/3250 <p>This study is ensuring the standard operative process (SOP) of <em>Sharpunkha Kshar (Lavana)</em> (alkaline extract of Tephrosia purpuria Linn.), as per classical text. It has hepato-protective effect. Many researches have been done on <em>Sharpunkha</em> extract but, no one work has been done on standardization of <em>Sharpunkha Kshar (Lavana)</em> yet. It was 1<sup>st</sup> mentioned by Acharya Bhavprakash in <em>Gulma chikitsa prakaran</em> by the name of <em>Sharpunkha Lavana</em>. During standardization of <em>Sharpunkha Kshar (Lavana)</em> raw drug authentication was done by microscopic and physico chemical analysis. lupeol, rutin, quercetin, rotenone and beta sitosterol biomarkers were screened in raw <em>Sharpunkha panchang</em> powder in HPTLC finger printing. <em>Kshara</em> was prepared by two different methods with 4 times (SPK-4) 6 times (SPK-6) water following standard protocols. Average 46.44% yield was obtained after drying of fresh <em>Sharpunkha panchang</em>. After burning of dry <em>Sharpunkha</em> average 5.03% ash was achieved. Average 16.3% <em>Kshar</em> yield in batch SK-4 and 16.6% <em>Kshar</em> yield in SK-6 was obtained. One more batch from residual ash was also prepared, 6.64% <em>Kshar</em> was obtained in it. Organoleptic, physico-chemical parameters were also done for both batch of <em>Sharpunkha Kshar (Lavana).</em> pH (12.65 &amp; 13.35 in SK-4, SK-6 respective) carbonate, bicarbonates, Na (0.56 &amp; 0.52%), and K (35.26, 35.41%) respectively present in batch SK-4 &amp; SK-6.</p> Manisha Goyal, Govind Sahay Shukla, Ravipratap Singh, Vishvendra Singh Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3250 Mon, 10 Jun 2024 00:00:00 +0800 Unveiling the Significance of Shodhan with Special Emphasis on Samanya Shodhana of Pittala https://ijapr.in/index.php/ijapr/article/view/3223 <p><em>Shodhana</em>, a crucial procedure in the pharmaceutical preparation of metals and minerals, aims to eliminate impurities and undesirable properties from raw materials, rendering them suitable for further processing. This study focuses on <em>Samanya Shodhana</em> of <em>Pittala,</em> a <em>Mishra Loha</em>, following the guidelines outlined in <em>Rasa Ratna Samucchya</em>. The process involves heating raw <em>Pittala</em> until red-hot and subsequently quenching it in <em>Tila Taila, Takra, Gomutra, Kanji</em>, and <em>Kulatha Kwatha</em> for seven iterations. Post-<em>Shodhana</em>, observations were made regarding the weight loss of <em>Pittala</em>, as well as pH and color changes in the respective liquid media. Results indicate a total weight loss of 7.0% in <em>Pittala</em> after <em>Samanya Shodhana</em>, suggesting effective impurity eradication.</p> Rolli Ghildiyal, Yadevendra Yadav, Shuchi Mitra, Usha Sharma, Khem Chand Sharma Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3223 Mon, 10 Jun 2024 00:00:00 +0800 Ayurvedic Interventions in Motor Neuron Disease https://ijapr.in/index.php/ijapr/article/view/3253 <p>Motor neurons are the neurons through which the brain exerts control over skeletal muscles of the body. Motor neuron diseases are rare&nbsp;heterogeneous group of neurologic disorders characterized by progressive degeneration of motor neurons.</p> <p>A 55-year-old woman diagnosed as motor neuron disease was admitted to Vaidyaratnam Ayurveda College Hospital, on 2/11/2023, for a 21 day duration, presenting with complaints of weakness of both upper limbs associated with muscle wasting predominantly on right shoulder and wrist since 1 year. The clinical and laboratory features suggested a diagnosis of brachial amyotophy diplegia, a regional variant of ALS.</p> <p>According to Ayurveda, <em>Avarana vatavyadhis</em> are found to have close resemblance to Motor Neuron Diseases and her symptomology can be correlated to <em>Kaphavruta Vyanavata</em>. The patient underwent <em>Avaranagna</em> and <em>Vata vyadhi chikitsa</em>. Assessment of the patient was done before and after treatment by physical examination, ALSFRS-R and Neuro QoL scale. A satisfactory improvement was observed with gradual gaining of upper limb strength and quality of life. This case study demonstrates that brachial amyotophy diplegia can be symptomatically managed with Ayurvedic therapy.</p> Aiswarya C R, Abdul Ravoof P K, T C Marikutty Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3253 Mon, 10 Jun 2024 00:00:00 +0800 The Efficacy of Wetcupping in Kateegraha (Low Back Pain) https://ijapr.in/index.php/ijapr/article/view/3258 <p>Among musculoskeletal disorders, low back pain (LBP) has the highest prevalence worldwide and is the primary cause of disability. This is the condition that has the highest potential for rehabilitation benefits Chronic LBP is a major cause of work loss and participation restriction and reduced quality of life around the world. In Ayurveda low back pain is correlated with <em>Kateegraha. Shringa avcharana</em> is one of the methods of <em>Raktamokshana </em>and this can be correlated with Chinese cupping method. The suction through specific cupped instrument was used since prehistoric time for the treatment of disease <strong>Objective</strong>: This case series aims to show how wet cupping affects lower back pain (<em>Kateegraha)</em>. <strong>Intervention:</strong> five patients who complained of low back pain were included to receive four sittings of wet cupping. Cups were applied on the lumbosacral region once every 7 days for 21 days. The visual analogue scale (VAS) and The Quebec Back Pain Disability Scale was used to evaluate the pain on 7 days, 14 days, and 21 days.<strong> Conclusion</strong>: It's been demonstrated that wet cupping works well for relieving <em>Kateegraha</em> (low back pain). So, we can conclude that for individuals with low back pain, wet cupping is a successful, safe, practical, and reasonably priced treatment plan.</p> Nimya M, Ambili Krishna, Manju P.S Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3258 Mon, 10 Jun 2024 00:00:00 +0800 Nuances in Ksharasutra Preparation Using Guggulu Extract https://ijapr.in/index.php/ijapr/article/view/3222 <p>Ano-rectal diseases are considered to be one of the conditions that affect a person's quality of life significantly. <em>Ksharasutra</em> (medicated thread) is a para-surgical procedure which is found more effective in the management of few among these conditions like fistula-in-ano and sinus. <em>Ksharasutra</em> is routinely prepared with <em>Snuhi ksheera</em> (latex of <em>Euphorbia</em> <em>nerifolia</em>), <em>Apamarga Kshara</em> (ash of <em>Acyranthes aspera</em>) and <em>Haridra</em> (powder of <em>Curcuma</em> <em>longa</em>). In conventional method, collection of <em>Snuhi ksheera</em> is time consuming, laborious and not available throughout the year. Here, <em>Guggulu</em> (Oleogum resin from <em>Commiphora mukul</em>) was selected as an alternative for <em>Snuhi ksheera</em> in the preparation of <em>Ksharasutra</em> as it is reported to have antiseptic, anti-inflammatory, wound-healing properties and it is available throughout the year. <em>Guggulu</em> was extracted using 95% ethyl alcohol, meanwhile <em>Apamarga</em> <em>kshara</em> was prepared in conventional way. Barbour linen thread no.20 was cut into 11 equal parts and mounted upon <em>Ksharasutra</em> frame. Each of which was later coated with 7,5,3 layers of <em>Guggulu</em> extract, combination with <em>Apamarga kshara</em> and combination with <em>Haridra</em> respectively. These were then kept under UV radiation in a cabinet and dried. After a speculated period of time the threads were cut down in a sterile condition, each (11 numbers) of them measuring 40 cm. These were then stored in an air-tight glass container. These <em>Ksharasutras</em> are prepared with a motive to get used in the management of the afore discussed ano-rectal conditions.</p> Alex Sebastian Chirayath, C Anju, Drishya H Bhat, Heera Hemaraj, P K Kripesh, M K Sreeshna Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3222 Mon, 10 Jun 2024 00:00:00 +0800 Management of Traumatic Perforation of Tympanic Membrane Through Ayurveda https://ijapr.in/index.php/ijapr/article/view/3218 <p>Traumatic tympanic perforations can occur due to various reasons, such as concussion, insertion of objects, temporal bone fractures, barotrauma, etc. Slap injuries are a common cause. Symptoms include sudden conductive deafness, pain and/or blood-stained discharge. Tinnitus and vertigo may complicate the condition. Appropriate and timely management is crucial to reduce the risk of permanent impairment, as studies indicate that spontaneous healing occurs within 1.5 to 3 months. While Ayurvedic texts don’t directly mention traumatic tympanic perforations, they can be categorized as <em>‘Agantuja</em> <em>Vrana’</em> (wounds caused by external factors). Ayurvedic treatment includes both local and systemic approaches. In this case study, medicines were used internally for 2 months: <em>Sarivadi</em> <em>Vati</em>, <em>Lakshadi</em> <em>Guggul</em>, <em>Mahayograj</em> <em>Guggul</em>, <em>Gandha</em> <em>Taila</em> capsules and a combination of <em>Vatashamaka</em> <em>Churnas</em>. This combination led to significant improvement; the perforation completely healed in 2 months. Thus, internal use of these drugs helped in the healing of traumatic perforations.</p> Pahwa Preeti, Saini Jasmeen, Vinaik Ashu Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3218 Mon, 10 Jun 2024 00:00:00 +0800 Understanding Dushta Vrana: An Ayurvedic Perspective on Various Characteristics of Chronic and Complex Wounds https://ijapr.in/index.php/ijapr/article/view/3224 <p>In the realm of Ayurveda, an ancient Indian system of medicine, the understanding of <em>Vrana </em>(wounds) extends far beyond mere physical injuries. Ayurvedic texts delve into the complex nature of chronic wounds and classify them under the umbrella term <em>"Dushta Vrana".</em> <em>Dushta Vrana</em> refers to non-healing, stagnant wounds resistant to conventional treatments, often requiring a multifaceted approach to facilitate the healing process.</p> <p>This review article aims to provide a comprehensive understanding of <em>Dushta Vrana</em>, shedding light on its diverse manifestations and underlying causative factors explained by <em>Acharya Sushruta</em> and <em>Acharya Dalhana</em>. By exploring the profound wisdom of Ayurveda, we can unlock potential solutions for the challenges posed by these persistent wounds. </p> Chhavi, Ajay Kumar Gupta Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3224 Mon, 10 Jun 2024 00:00:00 +0800 An Ayurveda Approach Towards Acute Sciatica with Paraesthesia https://ijapr.in/index.php/ijapr/article/view/3244 <p>Sciatica is pain or paraesthesia which is radiates path of the sciatic nerve and its branches from the lower back through the hips and buttocks and down to the leg. A 41-year-old female patient with an acute low back ache to radiate to left lower limb with paraesthesia for three months came to Kayachikitsa IPD of Vaidyaratnam Ayurveda College on 18/3/24. The pain was graded eight out of ten in the VAS pain scale and her overall Oswestry low back pain score is 32 which means severe functional disability. She underwent for <em>Vatakapha hara chikitsa</em> protocol. It includes <em>Rookshana, Snigda sweda, Vata hara, </em>and<em> Brihmana chikitsa</em>. Ayurvedic preparations like <em>Aadarisahacharadi kasayam, Suntibaladi choornam Vyoshadi guggulu</em> were given <em>Swedam, Patrapoliswedam, </em>and<em> Pizhichil, Shastika pinda swedam, Yoga vasti</em> along with passive exercise were given. After 30 days of treatment outcome of these treatments found to be very positive. There was a substantial recovery in walking duration, heaviness, touch temperature perception and pain relief was observed. Subjective parameters like, SLR test, Oswestry low back pain disability questionnaire, Sciatica bothersome index, Sciatica frequency index, Roland morris low back pain and disability questionnaire was taken for assessment parameters. The patient got relief in all parameters after treatment. It was proved significant improvement of patient’s primary symptoms. These therapies reduce pain, stiffness and improve circulation.</p> Chippy Soman, Navaneeth Krishnan N, Marikutty TC Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3244 Mon, 10 Jun 2024 00:00:00 +0800 Hearing Loss (Badhriya) and its Ayurvedic Management https://ijapr.in/index.php/ijapr/article/view/3252 <p>Hearing is an important medium, which keeps one connected to other and with the surroundings. Impairment of hearing and its severity may vary from mild to moderate or profound. It can be unilateral or bilateral and conductive or sensorineural or mixed type. <em>Acharya</em> <em>Sushruta</em> has explained 28 types of <em>Karna</em>-<em>roga</em> in <em>Uttar</em> <em>Tantra</em> an <em>Badhriya</em> is one of them. It is caused by <em>Vata dosha</em> or <em>Kaphaavritta</em> <em>vata dosha</em> by <em>Srotorodha</em> (obstructing of channels) of <em>Shabdavaha</em> <em>srotas</em> (pathway of hearing) and <em>Shabdavaha</em> <em>sira</em> (auditory nerve) and further ignorance of this condition leads to <em>Badhriya</em>. This case report presents 18 years old girl with hearing impairment in the right ear from 3 years. Audiometry reports shows moderate to severe mixed HL in right ear and left ear is normal. Treatment was done with <em>Marsha</em> <em>nasyam</em> with <em>Shadbindu</em> oil and <em>Karanpooran</em> with <em>Bilwadi</em> oil (right ear) for 7days. Along with <em>Sarivadi</em> <em>vati</em>, <em>Chandraprabha</em> <em>vati</em> as internal medicine for 1 month.</p> Sarita Sandhu, Jyoti Gupta Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3252 Mon, 10 Jun 2024 00:00:00 +0800 Rasamritam: A Comprehensive Study on Rasausadhies and Their Therapeutic Guidelines https://ijapr.in/index.php/ijapr/article/view/3259 <p><em>Ras Shastra</em> emerged in the Ayurveda medicinal tradition in addition to the use of minerals and metals. Numerous faiths, groups, and customs have influenced the evolution of <em>Ras</em> <em>Shastra</em>. As a result of this contribution, many books related to <em>Rasa Shastra</em> came into circulation. This tradition started from the medieval period and has persisted to the present time. Through <em>Rasamritm</em>, <em>Acharya</em> has actually presented the essence of the subject of <em>Ras</em> <em>Shastra</em> in this book in such a way that this book has actually become the nectar for the subject. This book contains the effective practical portion of the entire subject. It consist nine chapters and nine appendices in total. The text contains of both the theoretical and practical aspects. <em>Rasa yoga</em> are mentioned at the end of every chapter. Particularly, the ninth chapter only consist of <em>Rasa yoga</em>. Some of those are the new formulations, and some have been altered from the original text in some way. Few of the Unani formulations are also includes. The author also discusses possible chemical reactions and alterations while making <em>Rasaushadhies</em>. This article has been reviewed in order to gather all of the <em>Ras-yogas</em> mentioned in this text at one place. From this review, one can easily find the formulation with all the necessary information.</p> Shraddha Patel, Govind Sahay Shukla, Rajaram Agarwal, Manisha Goyal, Ravi Pratap Singh Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3259 Mon, 10 Jun 2024 00:00:00 +0800 Ayurvedic Management of Anxiety Induced Insomnia https://ijapr.in/index.php/ijapr/article/view/3227 <p>The extremely busy lifestyle has significantly impacted both the physical and mental health of individuals. Discussing mental health remains a stigma in society, profoundly affecting individuals' psyche. A male patient reported to the outpatient department with symptoms of anxiety, over thinking, disturbed sleep, body ache, fatigue, poor digestion, and frequent headaches for the past ten months. His score on the Hamilton Anxiety Rating Scale (HAM-A) was 30, indicating moderate to severe anxiety, and his score on the Pittsburgh Insomnia Severity Index (PSQI) was 17, classifying him as a poor sleeper. The patient underwent 42 days of Ayurvedic treatment, which included <em>Panchakarma</em> therapy and internal medications. The <em>Panchakarma</em> therapy consisted of <em>Abhyanga</em> with <em>Matra</em> <em>Basti</em>, <em>Shirodhara</em>, and <em>Pratimarsha</em> <em>Nasya</em> using <em>Bala Ashwagandhadi</em> oil. The internal medications included <em>Manasmitra</em> <em>Vataka</em>, <em>Chitrakadi</em> <em>Vati</em>, and <em>Kalyanak Ghrita</em>. After 42 days of treatment, the patient's HAM-A score decreased to 11, and the PSQI score dropped to 6. The patient reported a renewed sense of well-being and enthusiasm for work after a long time.</p> Bohra Mohita, Shukla Gyanendra Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3227 Mon, 10 Jun 2024 00:00:00 +0800 Addressing the Aging Process Through the Ayurveda Lifestyle Interventions and Adaptations https://ijapr.in/index.php/ijapr/article/view/3226 <p>The elderly population is growing worldwide, leading to an increased focus on geriatric care and promoting healthy aging. Ayurveda, an ancient Indian system of medicine, offers a holistic approach to healthcare that can be beneficial for addressing the unique needs of older adults. This research article explores the integration of geriatrics and Ayurveda, highlighting the potential benefits of Ayurvedic principles, lifestyle adaptations, and herbal remedies in geriatric care. By combining the wisdom of Ayurveda with modern geriatric practices, healthcare providers can offer comprehensive and personalized care to elderly individuals, enhancing their quality of life and promoting healthy aging. The field of geriatrics focuses on the healthcare needs of older adults, aiming to promote physical, mental, and emotional well-being in the elderly population. This study focus on enhancing the concept of geriatrics through the principle of Ayurveda related to lifestyle management. To minimize the functional decline and to enhance the quality of life in geriatric age group through the incorporation of Ayurveda lifestyle adaptation is the main goal of this paper. Lifestyle diseases are related with the people’s way of living. This is generally caused by lack of physical activity and unhealthy food habits. A healthy lifestyle must be adapted to fight the various age related disorders and diseases. Ayurvedic principles of health and disease focus on the concept of three <em>Doshas</em>: <em>Vata, Pitta and Kapha.</em> These are the three forces that determine the functioning of the body and mind. Although every person has all three <em>Doshas</em>, ​​we will each inherit them differently. This is responsible for the differences in our characters, likes, dislikes, attitudes and behaviours.</p> Vinita Patil, Vikram Sharma Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3226 Mon, 10 Jun 2024 00:00:00 +0800