International Journal of Ayurveda and Pharma Research https://ijapr.in/index.php/ijapr <div align="justify"> <p class="para1"><strong>International Journal of Ayurveda and Pharma Research (IJAPR)</strong>&nbsp;is an international peer reviewed Monthly open access Online and Print journal. The aim of the journal is to increase the impact of research in both academic and industry, with strong emphasis on quality and originality. The journal promotes to publish the articles in the field of&nbsp;<strong>Ayurveda, Siddha, Yoga, Naturopathy, Unani, Homeopathy and Allopathy</strong>&nbsp;systems of medicine and Pharmaceutical Sciences. Researchers may submit (1). Original Research Articles (2). Review articles (3). Book Reviews (4). Short Communications/ Research Letter (5). Case Report (6). Letter to the Editor/Correspondence.</p> </div> en-US editor@ijapr.in (Dr B Srinivasulu M.D (Ayu.)) Sun, 15 Sep 2024 00:00:00 +0800 OJS 3.1.2.1 http://blogs.law.harvard.edu/tech/rss 60 Evaluation of Shampakadi Basti and Kshar Basti along with Pristha Basti in Trik Grah (Ankylosing Spondylitis) https://ijapr.in/index.php/ijapr/article/view/3369 <p><em>Basti </em>is considered the most effective treatment for <em>Vata</em>, as well as for <em>Pitta, Kapha, and Rakta</em> (blood) in <em>Samsarga</em>, and <em>Sannipata Doshaas</em>. Within the <em>'Nanatmaja vyadhi'</em> of <em>Vata, Charaka sutra</em> 20/10 mentions a total of eighty types of <em>Vata Rogas</em>, known as <em>Ashiti Roga</em>. <em>Trik-Asthi</em> is sacrum bone. Sacroiliitis is often the earliest manifestation of ankylosing spondylitis. Ankylosing spondylitis is a complex, and systemic inflammatory rheumatic disease mainly affecting the axial skeleton, with the potential to cause severe debilitation. Fibrosis and ossification of tendon, ligament and capsule insertion at the area of sacroiliac and intervertebral discs are the main characteristics of ankylosing spondylitis. Eighty types of <em>Nanatmaja Vata Vikara</em> caused by <em>Vata</em>. <em>Trik Grah</em> one of the <em>Vata Nanatamaja</em> <em>Vyadhi</em>. <em>Vata-Vyadhies</em> can be considered as a group of such diseases, which Modern Science has given different names. <strong>Methods:</strong> This clinical study was done to “Evaluation of <em>Shampakadi Basti</em> and <em>Kshar Basti</em> along with <em>Pristha Basti</em> in <em>Trik Grah</em> (ankylosing spondylitis)”. <em>Basti Karma</em> is known to be the best for <em>Vata</em> disorders thus for this research, open labelled clinical study was done wherein 50 patients were taken in random manner having symptoms of <em>Trik Grah</em> and were divided into two groups, Group A received <em>Shampakadi Basti</em> along with <em>Pristha Basti</em> and Group B received <em>Kshar Basti</em> along with <em>Pristha Basti</em> daily for 8 days. <strong>Results:</strong> Evaluation and the result of both the group exhibited that the improvement provided by group B was better in both sign &amp; symptoms like <em>Sandhi Shool</em> (pain), <em>Sandhi Jadyata</em> (stiffness), <em>Angamarda</em> (fatigue), quality of sleep in comparison to group A. <strong>Conclusion: </strong>As <em>Vata</em> vitiation is a cause <em>Trik Grah,</em> no other treatment modality act as good as <em>Basti.</em> As <em>Ama </em>involvement was there, which was obstructing or vitiating the <em>Samanya Vata</em> action, thus <em>Shampakadi Basti</em> and <em>Kshar Basti</em> along with <em>Pristha Basti</em> showed encouraging results in&nbsp;this&nbsp;disease.</p> Mohit Bagwari, Piyush Gupta, Praphull Goyal, Ketan Mahajan Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3369 Sun, 15 Sep 2024 00:00:00 +0800 An Observational Study to Analyse the Stanya of Different Prakriti Females by Using Analyzer https://ijapr.in/index.php/ijapr/article/view/3370 <p>The functioning of <em>Doshas</em> commences at the very onset of life, specifically at the moment of conception. The balance of these three <em>Doshas</em>, integral to one's <em>Prakriti</em>, has the potential to interfere with the typical physiological processes in humans. <em>Doshas</em> and <em>Dhatus</em> exhibit a relationship characterized by <em>Ashrya-Ashrayee Bhava</em>. Each <em>Dhatu</em> is also associated with an <em>Updhatu</em>. <em>Stanya</em> and <em>Raja</em> are recognized as <em>Updhatus</em> of <em>Rasa</em> <em>Dhatu</em>. Since <em>Stanya</em> is an <em>Updhatu</em> of <em>Rasa Dhatu</em>, the factors that promote the formation of <em>Rasa Dhatu</em> will similarly enhance the development of <em>Stanya Updhatu</em>, and conversely. The determination of an individual's <em>Prakriti</em> is based on the predominance of <em>Doshas</em>. Consequently, the current research seeks to establish a connection between <em>Daihik Prakriti</em> and the components of <em>Stanya. </em><strong>Methods: </strong>This observational study done for biochemical analysis of <em>Stanya</em> and its correlation with <em>Daihik Prakriti</em>.. For this, 50 healthy lactating mothers were selected as subjects and their <em>Prakriti</em> were determined by using standard CCRAS performa. Breast milk were assessed for the different constituents in research laboratory and were compared later with <em>Prakriti</em>. Every sample of <em>Stanya</em> was examined by <em>Jala Pariksha</em>. <strong>Results:</strong> The result obtained shows that there is no significant correlation between <em>Prakriti</em> and fat, protein, SNF, lactose % levels, significant positive correlation between density and water % level with <em>Prakriti</em>, significant positive correlation was found on <em>Jal Pariksha</em> between color and appearance with different <em>Prakriti</em> and negative significant correlation between consistency and dissolution in water with <em>Prakriti. </em><strong>Conclusion:</strong> The results of biochemical analysis of milk for the attributes like density, Consistency, water percentage, color and <em>Jal Pariksha</em> have been in consistency with the properties mentioned by our <em>Acharyas</em> w.s.r to <em>Vata, Pitta</em> and <em>Kapha Pradhan dosha</em> thus inferring that the<em> Prakriti</em> has direct impact on the properties of <em>Stanya</em>.</p> Bhawana, Sharad Karande, Priyanka Wadhwa, Anurag Varshney, Shaveta Sawhney Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3370 Sun, 15 Sep 2024 00:00:00 +0800 A Comparative Clinical Evaluation of Janu Basti with and Without Upnaha in Janu Sandhigata Vata (Osteoarthritis of Knee) https://ijapr.in/index.php/ijapr/article/view/3371 <p><em>Sandhigata Vata</em> is the commonest form of musculoarticular disorder. It comes under eighty <em>Nanatmaja Vata Vyadhi </em>which mainly occurs due to <em>Dhatukshaya</em> in <em>Vriddhavasta</em>. <em>Janu Sandhi</em> is the major bearing joint in the body it’s more subjected to wear and tear. <em>Sandhi </em>comes under <em>Madhayam Roga Marga</em> where<em> Vata</em> gets localized in <em>Sandhi </em>thereafter <em>Shleshaka Kapha Kshaya</em> and cause symptoms like <em>Shoola, Shotha, Akunchana</em> <em>Prasarana Vedana, Vatapurna Driti Sparsha</em> which limits everyday activities such as walking, sitting and standing etc thus making patient disable to do daily activities. In the <em>Shastras</em>, <em>Acharya</em> Sushruta has firstly given the method of treatment such as <em>Snehana</em>, <em>Upnaha, Agnikarma, Bandhana, Mardana. Upnaha </em>is a type of <em>Sagni </em>and <em>Niragni Swedana</em>, which relieves stiffness, heaviness, cold and induces sweat. <em>Janu Basti</em> is type of <em>Bahya Snehana</em> and <em>Swedana</em>. It provides strength to the knee muscle, joints, and improves function of knee joint. In this study 50 patients having the complaints of osteoarthritis were randomly divided into 2 groups in Group A patients were treated with <em>Janu Basti</em> with <em>Upnaha </em>and in Group B were treated with only <em>Janu Basti</em>. The data shows that <em>Janu Basti</em> along with <em>Upnaha</em> i.e., group A has provided better relief in the disease of <em>Sandhigata Vata</em>.</p> Kiran Kumain, Ruchi Gupta, Prabhat Kumar, Ketan Mahajan Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3371 Sun, 15 Sep 2024 00:00:00 +0800 The Ancient Art of Discussion: Insights from Charaka Samhita https://ijapr.in/index.php/ijapr/article/view/3327 <p><em>Charaka Samhita</em> is an ancient Indian medical treatise that has stood the test of time. It covers a vast range of topics from fundamental principles of Ayurveda to the diagnosis, treatment and prevention of diseases. Its Wisdom has inspired generations of scholars and seekers of knowledge, shaping the evolution of Indian thought and culture. In order to attain scientific knowledge, three different means of knowledge (<em>Trividha jnanopaya</em>) are mentioned in Charaka Samhita. It includes <em>Adhyayana</em> (learning), <em>Adhyapana</em> (teaching) and <em>Tadvidya-Sambhasha</em> (discussions and debates). Among them, <em>Tadvidhyasambhasha</em> plays an important role in shaping the current form of <em>Charaka Samhita</em> making it accurate by rectifying the mistakes. This article is intended for analyzing various instances of <em>Tadvidya-Sambhasha </em>and their outcomes in Charaka Samhita.</p> Adarsh K R Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3327 Sun, 15 Sep 2024 00:00:00 +0800 An Overview of Immunomodulatory Activity of Rasayanas https://ijapr.in/index.php/ijapr/article/view/3300 <p>The term "immunomodulation" refers to the regulation and modulation of immunity, which may be accomplished by either enhancing or suppressing the immune response. A medication with immunomodulatory activity has particular importance given in the current state of pandemics, the rise in antibiotic resistance, and autoimmune diseases. A medicine with immunomodulatory properties that enhance quality of life would be great. Here lies the importance of <em>Rasayana tantra</em> which consists of many formulations aiming at increasing the quality of life by imparting longevity, memory, disease-free life, youth, excellence of body, and sense organs. Many <em>Rasayanas </em>have been shown to have immunomodulatory properties. <em>Rasayanas</em> have a calming effect on the psyche in addition to its intended benefits for physical health. It has also been demonstrated that stress affects immunity. Several <em>Rasayanas </em>have been shown to exhibit anti-stress properties. <em>Rasayana</em> may thus strengthen the psycho-neuro-immune axis and control the immune system by utilising the body's warriors, such as phagocytes and cytokines. Research on <em>Rasayanas</em> such as <em>Amalaki rasayana, Triphala</em> <em>rasayana, Chyavanaprasha</em>, etc. has been conducted both in vitro and in vivo. These kinds of studies establish the system as evidence-based and shed some light on the mechanism of action. The present review will provide knowledge about immunomodulatory activity and the action mechanism of <em>Amalaki rasayana, Triphala rasayana, Rasayana choorna, Shatavari</em> <em>Medhya rasayana </em>and<em> Chyavanaprasha</em>.</p> Sibina T P, Rajam R Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3300 Sun, 15 Sep 2024 00:00:00 +0800 Effects of Eight Week Supplementation of Ashwagandha and Amalaki Churna as a Rasayana w.r.t General Physical Fitness and Cardio-respiratory Endurance https://ijapr.in/index.php/ijapr/article/view/3340 <p>In India and around the world, people are spending more and more time enjoying sedentary lifestyle. This type of lifestyle decreases our physical fitness and compromises our cardio respiratory endurance. Under such circumstances along with a dynamic change in lifestyle and enhanced physical activity, there arises a need of drugs which can improve the physical fitness and cardio respiratory endurances among the youngsters and the adults. <strong>Purpose: </strong>The aim of the present study was to evaluate the efficacy of <em>Ashwagandha</em> and <em>Amalaki Churna</em> as a <em>Rasayana</em> with respect to general physical fitness and cardio-respiratory endurance. <strong>Material and Methods</strong>: 60 healthy individuals were registered for the present study. The individuals were divided into four groups. Each group comprised of 15 individuals. Group-I individuals were given <em>Amalaki Churna</em>, group-II individuals were given <em>Ashwagandha</em> <em>Churna</em>, group-III individuals were given both <em>Ashwagandha</em> and <em>Amalaki Churna</em> and group-IV individuals were given starch capsules as placebo therapy. The <em>Ashwagandha</em> and <em>Amalaki Churna</em> were given in the dose of 5gm each. Outcome measures: The study subjects were asked to perform tread mill test and TMT related parameters like exercise time, work load attained in terms of Mets, VO2 max, heart rate reserve index and rate pressure product were measured both before and after the completion of 8 weeks of therapy. Apart from this vital capacity and BMI were also measured. <strong>Results</strong>: After the therapy there was a statistically significant improvement in general physical fitness and cardiorespiratory endurance on various parameters in group-I, group-II, group-III, whereas placebo group did not show any statistically significant improvement. <strong>Conclusion</strong>: <em>Ashwagandha</em> and <em>Amalaki</em> improved the general physical fitness and cardiorespiratory endurance of the individuals.</p> Shilpi Mehra, Vijay Chaudhary Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3340 Sun, 15 Sep 2024 00:00:00 +0800 Ayurvedic Management of Ashmari (Nephrolithiasis) https://ijapr.in/index.php/ijapr/article/view/3360 <p><em>Mutrashmari</em> is one among the <em>Asta Mahagada</em> (eight fatal conditions) due to involvement of <em>Basti,</em> which is one of <em>Trimarma</em> and difficult to cure. It is <em>Kapha Pradhana</em> <em>Tridoshaja Vyadhi</em> due to clinical resemblance in clinical manifestation, <em>Mutrashmari</em> is compared to nephro-lithiasis or uro-lithiasis. Nephro-lithiasis is pathological condition of the urinary crystalloids takes place anywhere in the urinary tract. It is a big challenge for all health care systems. Because of changes in lifestyle, dietary habits, and treatment modalities its incidence and prevalence have increased significantly over the past few decades. Prevalence rate of kidney stone is about 11% in males and 9% in females, other diseases such as high blood pressure; diabetes and obesity may increase the risk for kidney stones. In Ayurveda<em>, Basti Chikista</em> is best for any obstruction or <em>Sroto-Sanga</em> in the body especially in the <em>Sthana</em> of <em>Vata Dosha</em> as <em>Pakwashya </em>(the main <em>Sthana</em> of <em>Vata Dosha</em>). Properties like <em>Teekshna, Ushna</em> and <em>Shothaghna, Mutra Virechaniya Karma</em> helps to eliminate the stone from urinary system and restore its functions. In the present case both <em>Shodhana</em> and <em>Shamana Chikista</em> were adopted. <em>Nabhi Purana</em> with <em>Ardraka Swarasa</em> reduced the colicky pain by pacifying the <em>Sthanika Vata Dosha</em>. <em>Mutra Virechaniya</em> (diuretic), <em>Ashmarighna</em> (litho-triptic) and <em>Shophaghna</em> (anti-inflammatory) are the way to reduce symptoms of renal stones. These medicines and therapeutics also helps to prevent recurrence.</p> Bishnupriya Mohanty, Shubhada Lekurwale, Abhishek Santosh Shriramjwar Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3360 Sun, 15 Sep 2024 00:00:00 +0800 A Classical Review on Metal Toxicity with special reference to Dhatu Varga https://ijapr.in/index.php/ijapr/article/view/3357 <p>A drug or formulation produces adverse events if it is not processed properly and used as per the classical guidelines. <strong>Aim and Objectives</strong>: In this review article, an attempt was made to throw some light on origins of those adverse drug reactions and various measures taken in literature. <strong>Material and</strong> <strong>Method: </strong>All the classical literature in<em> Rasagrantha</em>, <em>Sangraha grantha</em>, textbook of Ayurveda and <em>Rasashastra </em>regarding toxicity effect of <em>Dhatu varga </em>have been reviewed for this work. <strong>Observation and Result: </strong>For safe use of <em>Dhatu Bhasma</em>, various classical parameters at every stage of preparation and use have been stated. Starting from <em>Grahyagrayatwa</em> of raw metals, <em>Samanya Shodhana</em> of all <em>Dhatus</em>, toxic effect of improper processing of <em>Dhatu Bhasma</em>, and specific <em>Puta</em> for each <em>Dhatu</em> have been mentioned. Also, the <em>Amruti Karana </em>process, <em>Samanya</em> and <em>Vishesh Bhasma Pariksha </em>(parameters) have been exclusively done for the safety of <em>Dhatu Bhasma</em>. In order to reduce the residual toxic effect of <em>Bhasma</em> specific <em>Anupana</em> for specific <em>Bhasma</em> along with <em>Pathyapathya</em> have been detailed by ancient seers. Apart from that in case if any untoward effect has been found then the remedial therapies have been specified. <strong>Conclusion:</strong><em> Rasaushadhi</em> can cause adverse effect if not prepared as per the classical guidelines. Hence there needs to follow classical guidelines at each and every step of<em> Bhasma</em> preparation scrupulously to get standard quality of <em>Bhasma.</em></p> Sonbhoyar Devaki, Dongre Sushma Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3357 Sun, 15 Sep 2024 00:00:00 +0800 Interpretation of Streegata Adhika Peshi through the Principles of Peshi Shareera According to Sushruta Samhita https://ijapr.in/index.php/ijapr/article/view/3344 <p>Ayurveda a deeply human form of science, rooted in real-life outcomes obtained through extensive experimentation and research on all aspects that affect life. It offers insight into the intricate composition and functioning of human body (<em>Shareera</em>). The concept of <em>Shadangatvam </em>delves into the six main regions of body, while the <em>Pratyangas </em>provide further breakdowns of these regions. When exploring the <em>Pratyangas</em>, certain structures such as <em>Srotas</em>, <em>Peshi</em> and <em>Ashayas</em> the anatomical structures and physiological concepts will differ between genders. There are even discrepancies in numbers and structures. <em>Peshi Sankhya</em> varies according to gender. <em>Peshi</em> the building blocks of the human body originate from the <em>Mamsa dhatu</em>. They enclose the body like a sleeve, enveloping the <em>Sira, Snayu, Asthi</em>, and <em>Sandhi</em> by protecting and supporting these structures. Muscle tissue is a group of muscle fibers interconnected by connective tissue. They produce force and facilitate movement, regulating the body's internal environment. By directing the working of these muscles, the human mind ultimately manifests itself. The muscular system plays a key role in enabling the movement of the human body. This information about <em>Peshi </em>arouses curiosity about their anatomical structure described in ancient texts. This study examines the information and logically analyses and interprets it in order to determine the probable accurate anatomical structures.</p> Darshan J P Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3344 Sun, 15 Sep 2024 00:00:00 +0800 Assessing the Efficacy of Sneha Pottanam (Bundle Application) in Managing Vatha Related Diseases in Children https://ijapr.in/index.php/ijapr/article/view/3361 <p>The Siddha system of medicine offers a holistic approach that addresses not only physical ailments but also the spiritual well-being of individuals. It classifies 4,448 types of diseases and categorizes treatments into two types: internal and external medicines. <em>Pottanam</em> is one of the treatment methods described by Siddhar Therayar in his text ‘<em>Therayar Tharu’.</em> Managing special needs children has become a significant challenge today. <em>Sneha Pottanam</em>, an external therapy mentioned in <em>‘Pillaipini Vagadam</em> - Part 2’, is particularly used for managing <em>Vatha</em>-related disorders in pediatric cases. <strong>Aim &amp; Objective:</strong> The aim of this review is to elaborate the efficacy of <em>Pottanam</em> (bundle application) and to evaluate the therapeutic efficacy of <em>Sneha Pottanam</em>, as described in <em>‘Pillaipini Vagadam</em> – Part 2’, for the management of <em>Vatha</em>-related diseases through a comprehensive literature review. <strong>Materials &amp; Methods:</strong> The review was conducted through Siddha literature, including <em>‘Pillaipini Vagadam</em> – Part 2’, <em>‘Gunapadam’, ‘Pathartha Gunachinthamani’</em>, the ‘Manual of Siddha External Therapy’, as well as research articles from Google Scholar and PubMed. <strong>Discussion:</strong> Siddha literature describes a wide range of external therapies, with <em>Pottanam</em> being a simple yet effective treatment for managing spasticity in <em>Vatha</em>-related diseases and balancing the three humors. This therapy rejuvenates the body and stimulates nerve endings. The ingredients in <em>Sneha Pottanam</em> act intradermally, making it an excellent remedy for special needs children by enhancing the function of motor and sensory receptors. <strong>Conclusion:</strong> The pharmacological properties and phytocomponents of <em>Sneha</em> <em>Pottanam</em> are highly effective in managing spasticity in special children and balancing the elevated <em>Vatha</em> humor. This review supports further studies on the ingredients of <em>Sneha</em> <em>Pottanam</em>, which could aid in the management of neurological disorders caused by imbalances in the body's three humors.</p> T. Priyanka, D. Muthu Krishnan, S. Simal, C. Shanmuga Priya, A. Satheesh Kumar Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3361 Sun, 15 Sep 2024 00:00:00 +0800 Investigating Dream Phenomena in Ayurveda for Women: Diagnostic and Therapeutic Insights into Tridosha Imbalances https://ijapr.in/index.php/ijapr/article/view/3348 <p>This paper explores the role of dream phenomena in Ayurveda, particularly focusing on women. It examines how dreams are interpreted in relation to the <em>Tridosha</em> system <em>(Vata, Pitta, Kapha)</em> and their implications for diagnosing and treating <em>Dosha</em> imbalances. By integrating Ayurvedic principles with modern understanding of dreams, the study aims to provide a comprehensive framework for utilizing dream analysis in Ayurvedic practice. The analysis of dream patterns associated with <em>Dosha</em> imbalances among 50 women revealed notable trends in the frequency of dream experiences tied to each <em>Dosha</em>. The data showed that <strong><em>Pitta</em></strong> was the most frequently associated <em>Dosha</em>, with a total frequency count of 77 occurrences, representing 42% of the total dream patterns observed. This was followed closely by <strong><em>Vata</em></strong>, which accounted for 76 occurrences, or 41% of the total. <strong><em>Kapha</em></strong> had the lowest frequency with 39 occurrences, constituting 17% of the total. These results indicate that dream patterns reflecting fiery, intense, and chaotic elements were predominantly linked with <em>Pitta</em> imbalances, while disorganized and fragmented dreams were more commonly associated with <em>Vata. Kapha</em> imbalances, characterized by heavy and stagnant dream themes, were less frequent. The data suggests a significant correlation between specific dream phenomena and <em>Dosha</em> imbalances, highlighting the potential of dream analysis as a valuable diagnostic and therapeutic tool in Ayurvedic practice for understanding and addressing <em>Dosha</em>-related health issues in women.</p> Prachi, Sudheer Arya, Sapna Ratan Shah Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3348 Sun, 15 Sep 2024 00:00:00 +0800 A Case Study on Management of Shwitra Through Ayurveda https://ijapr.in/index.php/ijapr/article/view/3352 <p><strong>Introduction:</strong> Melanocyte degeneration has a connection to vitiligo, an acquired macular depigmentation disorder.&nbsp;It is thought to be brought on by cells' autoimmune destruction of melanocytes. Frequently symmetrical, generalized vitiligo affects the hands, wrists, feet, knees, neck, as well as the skin around bodily orifices. According to Ayurveda all the skin diseases are categorized under the <em>Kushtha Roga.</em> In the classics <em>Shwitra</em> is mentioned under <em>Kushtha Roga Chikitsa</em>. <strong>Methodology:</strong> The 10-year-old male child, complaint of white discolored spots on his neck and left clavicle region; <em>Shamana Chikitsa</em> was used to cure the condition satisfactorily.<strong> Result:</strong> Patient showed encouraging result after <em>Shamana Chikitsa</em>, where subjective criteria evaluated using scoring method and objective criteria evaluated using VASI scoring method. <strong>Discussion</strong>: Patient was treated with <em>Shamana Aushadhis</em>, where white discolored patches turned to pinkish, and after that the patches turned into normal skin color. Subject was observed with 95% improvement in subjective criteria and VASI scoring improved from 0.25 to 0.10. Hence, the present case study highlights the importance of efficacy of Ayurvedic treatment in <em>Shwitra</em>, as mentioned in classics.<strong> Conclusion: </strong>Ayurvedic medicine's effectiveness in curing <em>Shwitra</em> was confirmed by the current case study.</p> Krishna, Harish Kumar Singhal, Dinesh Kumar Rai Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3352 Sun, 15 Sep 2024 00:00:00 +0800 Rajata Shalaka Agnikarma - An Ethnic Perspective towards post-operative recurrent corn https://ijapr.in/index.php/ijapr/article/view/3353 <p>Melanocyte degeneration has a connection to vitiligo, an acquired macular depigmentation disorder.&nbsp;It is thought to be brought on by cells' autoimmune destruction of melanocytes. Frequently symmetrical, generalized vitiligo affects the hands, wrists, feet, knees, neck, as well as the skin around bodily orifices. According to Ayurveda all the skin diseases are categorized under the <em>Kushtha Roga.</em> In the classics <em>Shwitra</em> is mentioned under <em>Kushtha Roga Chikitsa</em>. <strong>Methodology:</strong> The 10-year-old male child, complaint of white discolored spots on his neck and left clavicle region; <em>Shamana Chikitsa</em> was used to cure the condition satisfactorily.<strong> Result:</strong> Patient showed encouraging result after <em>Shamana Chikitsa</em>, where subjective criteria evaluated using scoring method and objective criteria evaluated using VASI scoring method. <strong>Discussion</strong>: Patient was treated with <em>Shamana Aushadhis</em>, where white discolored patches turned to pinkish, and after that the patches turned into normal skin color. Subject was observed with 95% improvement in subjective criteria and VASI scoring improved from 0.25 to 0.10. Hence, the present case study highlights the importance of efficacy of Ayurvedic treatment in <em>Shwitra</em>, as mentioned in classics.<strong> Conclusion: </strong>Ayurvedic medicine's effectiveness in curing <em>Shwitra</em> was confirmed by the current case study.</p> Kashikar Prathamesh Pradeep Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3353 Sun, 15 Sep 2024 00:00:00 +0800 Effect of Virechana on CRP in a Patient of Metabolic Syndrome https://ijapr.in/index.php/ijapr/article/view/3330 <p>Metabolic Syndrome is a result of metabolic impairment involving multiple systemic manifestations. Over nourishment, deposition of visceral fat, physical inactivity, sedentary lifestyle, genetic predisposition, familial tendency, mismanagement of physical or mental stress, irregular sleep- wake cycle, etc. These metabolic errors are actually resulted by indulging in the etiological factors that cause <em>Medodushti</em> in turn leading to <em>Medoroga</em>. Such etiological factors are called as <em>Santarpana karaka</em> <em>Nidanas</em> which include the food articles that are rich in <em>Snigdhamsha, Madhura rasa, Guru </em>and <em>Pichchila gunas</em> and also the activities that favour excessive nourishment and deposition of <em>Meda Dhatu</em>. This abnormally nourished <em>Medo dhatu</em> will contain <em>Ama</em> which further damages to manifest into metabolic syndrome. <em>Virechana </em>is a type of<em> Shodhana Karma – </em>Biopurification process that is potent enough to cleanse the channels and bring vitality to the <em>Dhatus</em> in the body. It is said to be improving bioavailability of medicines by cleansing at intestinal level and also by enhancing the demand and supply mechanism at tissue level. By removing the debris and unwanted accumulations in the channels, <em>Virechana</em> acts as <em>Sroto vishodhaka</em> and <em>Medo hara</em> also. By removing excess <em>Kledamsha</em> from the body, it reduces oedema, inflammation and also improves tissue permeability. <strong>Aim</strong>: To assess the effect of <em>Virechana</em> in metabolic syndrome, dyslipidaemia. <strong>Methodology</strong>: Administration of <em>Amapachana</em> followed by <em>Virechana karma</em>. <strong>Result:</strong> There was marked improvement in signs, symptoms and biochemical parameters after intervention. <strong>Conclusion:</strong> <em>Virechana</em> is significantly effective on altered levels of lipids, elevated blood sugar level and also raised ESR.</p> Mamata Bhagwat, Shrilatha Kamath T Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3330 Sun, 15 Sep 2024 00:00:00 +0800 An Ayurvedic Approach in Secondary Infertility https://ijapr.in/index.php/ijapr/article/view/3333 <p>Infertility is a major concern among the people of reproductive age due to various causes. This is a case study of an infertile couple who had not been able to conceive for 2 years and 8 months of unprotected sexual life and had a history of abortion. Patient was diagnosed with PCOS (Polycystic Ovarian Syndrome). The objective of interventions included Ayurvedic management for abortion and ensuring nourishment of uterus and regular ovulation. This helps in facilitating healthy pregnancy and ensuring childbirth. Based on the parameters of Ayurveda, this case was diagnosed as <em>Garbhasravi Vandhyatva</em> (secondary infertility due to recurrent abortions). Treatment plan included both <em>Shodhana</em> (purification) followed by <em>Uthara vasthi</em> and <em>Shamana</em> (mitigation) therapies. The outcome of the Ayurvedic intervention was the conception of the patient after three courses of Ayurvedic treatments and was delivered with a healthy baby boy.</p> Prasanna V N, Amal Rose K R, Nandhana Gosh, Anna Rose Joju, Durga M R Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3333 Sun, 15 Sep 2024 00:00:00 +0800 Conceptual Study of Shatkriyakala in Shuskashipaka (Dry Eye Syndrome) https://ijapr.in/index.php/ijapr/article/view/3356 <p><em>Shushkakshipak</em><em>a</em> is considered as a <em>Sarvakshi roga</em> by Ayurveda acharyas. Among different Acharyas there is difference in opinion about the <em>Dosha</em> predominance of the disease. According to Susruth Acharya it is a <em>Vataja</em> disease; but Vagbhata describes it as a <em>Vatapitta</em> entity. <em>Vata, Pitta</em> and <em>Rakta</em> play major roles in the pathogenesis of <em>Sushkakshipaka</em>. The term <em>Kriyakala</em> refers to the progress of the disease, which helps to determine the treatment modalities to be given to make the <em>Doshas</em> in equilibrium. The <em>Kriya Kala</em> explained by Susrutha is having six stages, consider as <em>Shadkriyakala.</em> Here is an attempt to explain <em>Shushkakshipaka</em> in terms of <em>Shadkriyakala</em> so that one can understand the stage of the disease and decide the treatment to be given.</p> Jinoop.P, Narayan Bavalatti, Manjusha Rajagopala, Prabi K P Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3356 Sun, 15 Sep 2024 00:00:00 +0800 Clinical Importance of Agrya Ausadha Aragvadha in the Management of Vicharchika: A Pharmacological Review https://ijapr.in/index.php/ijapr/article/view/3358 <p>In Ayurvedic clinical practice, <em>Agrya ausadha</em> are the first drug of choice for treatment of various diseases. <em>Aragvadha</em>, as an <em>Agrya ausadha</em>, is employed for its therapeutic benefits in both internal and external applications. It is notably used for <em>Mridu</em> <em>virechana</em> (mild purgation) and as a topical remedy for various types of <em>Kustha</em>. In Ayurvedic dermatology <em>kustha</em> has been taken as supreme word for all skin diseases<em>. Vicharchika</em>, classified as a <em>Kshudra Kustha</em>, is treated through the dual principles of <em>Sodhana</em> (purification) and <em>Samana Chikitsa </em>(pacification). The <em>Majja</em> (pulp) of <em>Aragvadha</em> is utilized for internal <em>Sodhana</em> therapy, while the leaves are applied externally as a paste for <em>Samana Chikitsa.</em> Preliminary findings indicate that <em>Aragvadha</em> meets the criteria for an ideal drug as per classical Ayurveda, given its accessibility (<em>Bahuta</em>), versatility in formulations (<em>Anekvidhkalpana</em>), and effectiveness (<em>Yogatyam</em>). <em>Aragvadha</em>, through its varied formulations, plays a crucial role in the Ayurvedic management of <em>Vicharchika</em>. Its use aligns with the principles of <em>Sodhana </em>and <em>Samana Chikitsa</em>, offering a comprehensive approach to treating this skin disorder. The study highlights the clinical significance of different parts of <em>Aragvadha</em> and supports its continued use in Ayurvedic dermatological practice.</p> Manisha B, Suresh C, O.P. Singh, Sanjay Kumar Singh Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3358 Sun, 15 Sep 2024 00:00:00 +0800 A Pharmacodynamical and Therapeutic Potential of Sthavar Visha w.r.t. Visha Guna https://ijapr.in/index.php/ijapr/article/view/3334 <p>Ayurveda always emphasized the two aspects i.e., concept of <em>Sukham dukham</em> <em>ayu</em> or <em>Hitam- ahitam.</em> This <em>Dvandaj</em> relationship helps us to understand the concept of useful nature of <em>Visha dravya</em>. It’s remarkable how the <em>Visha dravya</em> present in nature has been utilized by the knowledge of Ayurveda to the benefit of human beings. <strong>Aim:</strong> To review the <em>Rasapanchak </em>of <em>Sthavar visha</em> with the 10 <em>Guna </em>of <em>Visha </em>mentioned in Schedule E (1) drug &amp; <em>Upvisha.</em> <strong>Objective:</strong> To compare the similar <em>Gunas</em> of <em>Sthavar visha</em> with <em>Visha guna.</em> <strong>Material &amp; Method:</strong> Plants mentioned in schedule E of Drugs &amp; Cosmetic Act 1945, were studied for their <em>Dravyaguna</em> properties and obtained from the <em>Dravyaguna vigyan</em>. The rules and regulation related with poisonous drugs are given in Drugs &amp; Cosmetic Act 1945. Relevant information related to <em>Visha </em>was collected from the Ayurvedic text, databases, books affiliated with <em>Agad Tantra</em>. <strong>Result:</strong> There are 14 drugs of plant origin mentioned in schedule E (1) along with the safety studies and packing of these drugs guidelines in drugs and cosmetic act 1945, 1 drug of animal origin and 7 drugs of mineral origin. Out of 10 <em>Gunas</em> of <em>Visha</em> 6 <em>Gunas </em>i.e.,<em> Laghu, Tikshna, Ruksha, Vyavayi, Vikasi </em>and<em> Sukshma</em> are similar to <em>Gunas</em> of poisonous plants. <strong>Conclusion:</strong> Due to similarities in <em>Visha guna</em> there is separate category of <em>Sthavar visha</em> (poisonous drugs) which makes them different from other plant drugs, along with their different mode of action which is similar to action of <em>Visha</em>. There is a need of detailed safety studies of these drugs to make them recognizable at global health.</p> Tanvi Gusain, Brijendra Singh Tomar, Satbir Kumar Chawla Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3334 Sun, 15 Sep 2024 00:00:00 +0800 Ethno Medicinal Knowledge and Practices in Gandhamardan Hills: An In-Depth Survey https://ijapr.in/index.php/ijapr/article/view/3374 <p>This document lists twenty plant species that have historically been utilized to treat a variety of illnesses and health problems by the most well-known ethnic tribe in the Gandhamardan hill region. Firsthand information gathered from key tribal communities in the Gandhamardan hill region of the Balangir districts of Odisha through a number of surveys and field trips. A result of the ethno-medical study is presented, including local names, botanical names, families, locations of collecting, and methods of administration. The article highlighted the distinctive variety of plants found in this hill range and the actions necessary to protect the endangered species.</p> Bal Nigamanand, Das Arun Kumar Copyright (c) 2024 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 https://ijapr.in/index.php/ijapr/article/view/3374 Sun, 15 Sep 2024 00:00:00 +0800