International Journal of Ayurveda and Pharma Research https://ijapr.in/index.php/ijapr <div align="justify"> <p class="para1"><strong>International Journal of Ayurveda and Pharma Research (IJAPR)</strong>&nbsp;is an international peer reviewed Monthly open access Online and Print journal. The aim of the journal is to increase the impact of research in both academic and industry, with strong emphasis on quality and originality. The journal promotes to publish the articles in the field of&nbsp;<strong>Ayurveda, Siddha, Yoga, Naturopathy, Unani, Homeopathy and Allopathy</strong>&nbsp;systems of medicine and Pharmaceutical Sciences. Researchers may submit (1). Original Research Articles (2). Review articles (3). Book Reviews (4). Short Communications/ Research Letter (5). Case Report (6). Letter to the Editor/Correspondence.</p> </div> International Journal of Ayurveda and Pharma Research en-US International Journal of Ayurveda and Pharma Research 2322-0902 Pharmaceutical and Physico Chemical Analysis of Tuttha Bhasma https://ijapr.in/index.php/ijapr/article/view/2129 <p><em>Rasa sastra</em> is an ancient science dealing with various drugs of mineral and metallic origin <em>Tuttha </em>(copper sulphate) is a mineral useful in various clinical conditions externally as well as internally. According to <em>Rasasastra,</em> through the process of <em>Shodhana</em> (purification) and Marana (incineration) the harmful effects of <em>Tuttha bhasma</em> (incinerated copper sulphate) is nullified resulting in the formation of a newer compound that is therapeutically more potent. To prepare <em>Tuttha Bhasma </em>by adopting standard manufacturing procedure explained in Ayurvedic texts as well as to study it’s physical and chemical characters using traditional and modern analytical tools. The pharmaceutical processing of <em>Tuttha bhasma</em> was carried out in three <em>Kukkuta puta </em>(incineration) with a peak temperature of 610<sup>0C</sup> according to <em>Rasa Tarangini</em> reference. Physico chemical analysis, Energy-Dispersive X-ray Fluorescence (EDXRF), X-ray Diffraction (XRD), Particle Size Analysis (PSA) were conducted. The final product shows presence of nano particles which was confirmed by particle analysis. XRD results of <em>Tuttha bhasma</em> revealed the presence of copper sulphide (covellite) with hexagonal lattice and sodium sulphate with orthorhombic structure. All of the preparation stages and changes in the properties were documented and validated, and they may now be used as a valuable tool for standardization and quality assurance of <em>Tuttha bhasma.</em></p> Anjana V Mani R Rajam Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 1 8 10.47070/ijapr.v9i11.2129 Pharmaceutical Study of Arkamanashiladi Tailam https://ijapr.in/index.php/ijapr/article/view/2114 <p>Superficial skin infections are very common in present day clinical practise. Contemporary physicians find it difficult to treat these dermatological manifestations due to long treatment duration, development of resistance and adverse drug events. Description about skin diseases are seen in Ayurveda classics like Charaka and Sushrutha under the heading of <em>Kushta </em>(skin diseases). <em>Kandu</em> (itching) is one of the primary symptoms in most of the <em>Kshudra Kushtas</em>. Chakradatta described a herbo mineral preparation named as <em>Arkamanashiladi Tailam</em> which acts as <em>Kandughna </em>(reduces itching) and <em>Pamakushtahara </em>(eradicates skin diseases). This formulation contains <em>Arkapatra swarasa </em>(Juice of <em>Calotropis</em> <em>gigantea</em><em>)</em>, <em>Shoditha Manashila</em> (Realgar), <em>Nisa kalka </em>(Paste of turmeric) and <em>Sarshapa Tailam </em>(Mustard oil). Preparation of <em>Arkamanashiladi Tailam</em> carried out according to general method of preparation of <em>Sneha kalpana </em>after the purification of <em>Manashila</em>. After considering all <em>Pakasiddhi lakshnas</em> like <em>Phenodgama </em>(appearance of froth), <em>Shabdahina </em>(absence of sound) etc. final product obtained which is dark brown in colour and stench smell. As there is no Analytical study reports available for <em>Arkamanashiladi tailam</em> to ensure its quality. Hence, in this present study different analytical parameters including Organoleptic characters, pH, Specific gravity, Refractive index, Saponification value, Iodine value, Acid value and Moisture content has been evaluated as per Ayurvedic pharmacopoeia of India. All the parameters were found to be within the reference standards and these can be used for further studies on Arkamanashiladi tailam standardization.</p> Mrudula Divakaran K L Virupaksha Gupta Saravanan B Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 9 14 10.47070/ijapr.v9i11.2114 Antibacterial Efficacy of Mouth Rinsing With 0.4% Syzygium Cumini Leaf Extract Against Streptococcus Mutans: A Randomized Controlled Trial https://ijapr.in/index.php/ijapr/article/view/2154 <p><em>Syzygium cumini</em> leaf extract possess a range of pharmacological properties such as anti-diabetic, anti-inflammatory, antiulcerogenic, cardioprotective, antidiarrheal, antimicrobial, antioxidant and hepatoprotective activities. Objective of the study was to evaluate and compare the antibacterial efficacy of 0.4% <em>Syzygium cumini </em>leaf extract and 0.2% chlorhexidine containing mouthwashes on salivary Streptococcus mutans among children aged 7-8 years in a hospital setting. <strong>Methods: </strong>Twenty-four<strong> s</strong>chool children aged 7-8 years, fulfilling the eligibility criteria, were randomized into two groups. Group 1: received 0.4% S. cumini leaf extract mouth wash and Group 2: received 0.2% chlorhexidine mouth wash. Saliva samples of the children were collected before and one hour after mouth rinsing with 10 ml of interventional mouthwash, for S. mutans count analysis. <strong>Results: </strong>The results of the study showed that there was significant reduction in salivary S. mutans counts in both the groups post mouth rinsing with interventional solutions (p=0.002). However, intergroup comparison reveled that in Chlorhexidine group there was significantly more reduction in Salivary S mutans counts compared to <em>Syzygium cumini</em> mouth rinsing group. (p=0.03) <strong>Conclusion: </strong>There was reduction in salivary S mutans counts after mouth rinsing with <em>Syzygium cumini</em> leaf extract. Hence, <em>Syzygium cumini</em> leaf extract mouthwash could be an effective aid for prevention and control of dental caries since it is safe, culturally acceptable and feasible.</p> Aniruddha Das Puja C Yavagal Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 15 18 10.47070/ijapr.v9i11.2154 A Case Report on Ayurvedic Management of Dushta Vrana https://ijapr.in/index.php/ijapr/article/view/2174 <p><em>Dushta vrana </em>is a commonly encountered problem in day-to-day practice. Contemporary progress in the field of surgery has reduced the incidence of wound infection to a great extent along with the use of antibiotics. But still the management of ulcer encounters many glitches. This case study discusses about a 58-year-old male patient who presented with a chronic non healing ulcer in the anterior aspect of the left ankle joint associated with pain, burning sensation, foul smelling and inflammation with no history of varicose veins. Patient was treated with <em>Karaskara ksheera kashaya</em> <em>dhara</em> followed by dressing with <em>Jathyadi ghrta</em>. <em>Punarnavadi kashayam</em> and <em>Guggulupanchapala</em> <em>choornam</em> was given internally for a period of 35days. <em>Virechana</em> with <em>Avipathy Choornam</em> was given once during the whole course of the treatment. <em>Raktamokshana</em> was done twice as <em>Jaloukavacharana</em>. In order to enhance the speedy recovery, traditional use of <em>Kupeelu </em>was considered. A highly potent drug among the <em>Upavisha</em> which is well known for properties like <em>Vranahara, Soolahara, Kushtahara, Sothaghna </em>etc. which augments the peripheral blood circulation, reduces pain, burning sensation and inflammation. The wound healed within a period of 35 days and got complete relief from pain, burning sensation and swelling. Thus, the patient was successfully treated with no complications.</p> Neethi Rajan C.K Krishnan Nair Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 19 22 10.47070/ijapr.v9i11.2174 A Clinical Study of Maltyadi Tail in the Management of Darunak W.R.S. To Dandruff https://ijapr.in/index.php/ijapr/article/view/2112 <p><em>Darunak</em> is a <em>Vata –Kaphaj Vyadhi</em>. <em>Sushruta </em>mentioned it under <em>Kshudra roga</em>.<em> Chakradatta </em>has mentioned application of <em>Maltyadi Tail </em>(<em>Jaati, Karveer, Chitrak, Karanj</em>, base oil- <em>Tila Tail</em>) in the treatment of <em>Darunak</em>. Aggravation of <em>Kapha</em> and <em>Vata</em> in <em>Darunak</em> causes, itching, falling of hair, loss of sensation, dryness and small cracks of the skin of the scalp. Several factors increase the risk of developing dandruff, including a person’s age, the weather, stress levels, fungus, medical conditions, and choice of hair products. Oiling is the best way to get a healthy scalp. <strong>Aim and objective:</strong> To evaluate efficacy of <em>Maltyadi Tail</em> in the management of <em>Darunak</em> w.s.r to dandruff. <strong>Materials and Methods:</strong> In this clinical study total 46 Patients of <em>Darunak</em> were registered out of which 3 patients left the treatment; remaining 43 patients were divided into 2 groups. 23 patients were treated in group A (test drug-<em> Maltyadi</em> <em>Tail</em>) and 20 patients were treated in group B (control drug-<em> Tila</em> <em>Tail</em>) for 30 days. The effect of therapy was assessed on the basis of changes in grading score. <strong>Result: </strong>In clinical study, All the cardinal and associate symptoms except <em>Raag, Daah, Ruja</em> were statistically significant improved after the complete course of test drug (<em>Maltyadi Tail</em>). Effect of Group A reduced <em>Kesha Bhoomi Rookshta</em> by 92.68%, <em>Kandu</em> by 100%, <em>Keshbhoomi Prapatan</em> by 92.68% and <em>Keshchyuti</em> by 87.50% which was statistically highly significant. <strong>Conclusion: </strong>The study revealed that test drug (<em>Maltyadi</em> <em>tail</em>) is more effective in <em>Darunak</em> /dandruff compare to control drug (<em>Tila Tail)</em>.</p> Deepti Negi Anoop Kumar Singh Vipin Kumar Shweta G Shukla Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 23 27 10.47070/ijapr.v9i11.2112 Effect of Navajivana Rasa with Pathyashadangam Kashaya Ghanasatwa in Classical Migraine - An Open Label Single Arm Pilot Study https://ijapr.in/index.php/ijapr/article/view/2127 <p>Migraine is the second most common cause of primary headache and as per GBD 2015; migraine was ranked third highest cause of disability worldwide. Migraine with aura is an episodic headache associated with certain features such as sensitivity to light, sound or movement; nausea, vomiting and various fully reversible neurological symptoms. The aim of study was to assess the effect of <em>Navajivana rasa</em> with <em>Pathyashadangam kashaya ghanasatwa</em> in Classical Migraine. The formulations were combined and made into a dispensable form of hard gelatin capsules. Selected participants were given with two 500mg capsules twice daily after food for 2 months and were observed during 1 month of follow up. Symptomatic features were assessed before treatment, after 2 months of medication &amp; after follow up. The MIDAS score for the assessment of disability was assessed before and after 3 months of study period. The results showed that, the study drug was effective in relieving the sign &amp; symptoms of classical migraine and in improving the quality of life.</p> Rohith.M.R S.Thara Lakshmi Kusumam Joseph Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 28 32 10.47070/ijapr.v9i11.2127 Effect of Lakshmi Vilasa Rasa and Bala Gulucyaadi Kashaya in Pain of Knee Osteoarthrits - A Case Report https://ijapr.in/index.php/ijapr/article/view/2126 <p>Knee OA is a chronic disease that affects the entire joint, including the articular cartilage, meniscus, ligament, and peri-articular muscle, and can be caused by a variety of pathophysiological causes.<em> Lakshmi vilasa rasa </em>(LVR) is a <em>Khalviya Rasayana</em> mentioned in the <em>Visha upavishadi Vijnaneeya Taranga</em> of <em>Rasa Tarangini</em> indicated for <em>Roga durbala deha, Krsa, Dehapushti, Vahnimandya</em>. <em>Bala guluchyaadi kashaya </em>(BGK), is mentioned in <em>Chikilsamanjari's Vatarakta prakarana. </em>This work explores a case study on the combined effect of these two drugs in pain of knee osteoarthritis. Assessment was done before and after treatment with the help of VAS scale and WOMAC scale CRD version. The results showed that <em>Lakshmi vilasa rasa </em>with <em>Bala guluchyaadi kashaya </em>was effective in relieving pain, stiffness and improving the physical function</p> Archana V S Thara Lakshmi Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 33 37 10.47070/ijapr.v9i11.2126 Survey on Prevalence of Vegadharana as a Risk Factor for Cardiac Disorders- An Observational Pilot Study https://ijapr.in/index.php/ijapr/article/view/2081 <p>The present era, which is a reflection of changing major driving forces such as social, economic and cultural due to globalization, urbanization and population ageing. By this change, there is raise in the prevalence of certain non-communicable diseases. Cardiac disorders are among such which stands first in increasing mortality rate about 31% globally. Now a day, the prevalence rate is increasing due to behavioral risk factors like tobacco use, unhealthy diet, obesity, physical inactivity, alcohol and smoking. People are also at higher risk of these disorders with the presence of high risk of one or more already established disease conditions like Hyperlipidemia, Hypertension, Diabetes mellitus etc. Indians are being affected by high rates of these major risk factors which are striking for cardiac disorders at an earlier age almost 33% earlier than other demographical regions.</p> <p>Considering all these many organizations like MRFIT, American Heart association, National Lipid organization etc. are conducting various trials since four decades to establish the appropriate relation with risk factors to plan the better lines of management. Ayurveda explains about the concept of <em>Dharaneeya</em> and <em>Adharaneeya vegas</em>, where in Acharyas emphasize that many of the systemic diseases are caused by the forceful suppression of natural urges. Among 13 <em>Dharaneeya</em> <em>vegas</em> 9 are found to be the risk factors in causing various cardiac disorders. With this regard to explore and to assess the prevalence of <em>Vegadharana</em> as risk factor for cardiac disorders, an attempt has made as a pilot survey study on 40 cardiac patients. <strong>Aim: </strong>To understand the Prevalence and epidemiology of <em>Vegadharana</em> in Cardiac disorders. To observe the Co-relation between <em>Vegadharana</em> and Cardiac disorders. <strong>Methodology: </strong>It is a Pilot observational study done by using a survey strategy. The questionnaire method in an electronic format was used to collect the data. Descriptive statistics and Co-relation Co-efficient was used to analyze the data obtained. <strong>Result: </strong>In this Pilot study, the sum of the prevalence of <em>Vegadharana</em> was observed it was found that the frequency of <em>Vegadharana</em> was more in cardiac individuals, especially the category of few times and sometimes with n value=76 and 64 respectively. <strong>Conclusion:</strong> With the above data, it can be concluded that; <em>Vegadharana</em> has an impact on the expectancy of Cardiac disorders. The data also revealed the co-relation of <em>Vegadharana</em> in permutation which are signifying as higher risk factors in causing cardiac disorders.</p> Lolashri S.J Kiran M Goud Prasanna Kulkarni Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 38 45 10.47070/ijapr.v9i11.2081 An Overview on Hitopadesa Vaidyaka https://ijapr.in/index.php/ijapr/article/view/2103 <p>Ayurveda, the science of life is dated back to thousands of years. In ancient times the knowledge of this system were passed orally from teachers to students. In course of time scholars began to record their knowledge in the form of treatises like <em>Charaka Samhita, Susruta Samhita</em> etc. Later many <em>Acharyas</em> composed their own treatises on the basis of knowledge they acquired as well as their own observations and experiences. <em>Madhava Nidana, Sarangadhara Samhita, Bhavaprakasa, Kasyapa Samhita</em> etc. are such contributions by various scholars. The ancient knowledge is updating by new physicians through the observations they made in relation with changes in <em>Kala </em>(time), <em>Desa</em> (place), availability of medicines, newly emerging diseases etc. So it is necessary to explore such treasures of knowledge.</p> <p><em>Hitopadesa</em> <em>vaidyaka</em> is a work on Ayurveda which gives emphasis on the diagnosis of disease as well as treatment through simple medicinal formulations. The book starts with <em>Ashtasthana pareeksha</em> where <em>Nadi pareeksha</em> is given utmost importance and provides description of <em>Jvara </em>etc. diseases with brief description on <em>Lakshana </em>(clinical features) and detailed description on <em>Chikitsa </em>(treatment). The author has given priority to simple formulations using easily available <em>Oushadhas</em> (medicines) the effect of which are established by the author himself through his clinical experience. Some diseases mentioned in ancient treatises are not found in this text whereas some new diseases are included. As the book found worth study, this paper aims at an overview on the treatise <em>Hitopadesa</em> <em>Vaidyaka</em>.</p> Ujitha Kuttan K Braivin Camly R Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 46 50 10.47070/ijapr.v9i11.2103 A Review on Swarna Kalpas Mentioned in Rasaratnasamucchaya https://ijapr.in/index.php/ijapr/article/view/2119 <p><em>Rasasastra</em> an independently originated science which became a significant part of Ayurveda deals with the pharmaceutics and therapeutic aspects of the metals and minerals. <em>Rasaratna samucchaya</em> is a well known <em>Rasasastra</em> textbook which describes both the aspects of various <em>Rasaushadhis</em>. A literature review on <em>Swarna kalpas</em> mentioned in <em>Rasaratna samucchaya</em> has been conducted here. The available data was classified and tabulated in the order of chapters. A total of 52 formulations were identified with presence of <em>Swarna</em> as an ingredient and among them, more number of formulations (10) were mentioned in <em>Vajikarana adhyaya</em> compared to other chapters.</p> Rohith.M.R S.Thara Lakshmi Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 51 58 10.47070/ijapr.v9i11.2119 Carpal Tunnel Syndrome (CTS): Work-Related Musculo-Skeltal Disorder and its Intervention in Ayurveda https://ijapr.in/index.php/ijapr/article/view/2082 <p>Today the desk/chair-hand combination became the cultural norm in the workplace. Typical seated worker has risk of musculo-skeltal disorders same as lifting heavy weights on job. CTS is one of the musculo-skeletal disorder and is due to overuse, strain, forceful or stressed motion of hand and wrist. Activities or jobs that require repetitive flexion and extension of the wrist may contribute such as computer work, sewing, writing, playing instruments, and driving for long duration. Its Risk factors include RA&nbsp;or other wrist arthritis, Diabetes etc. In Ayurveda increase or vitiation of <em>Vata</em> results in compression and pain which is present in CTS. Ayurveda management of Carpal tunnel syndrome involves the management of vitiated <em>Vata</em> <em>Dosha</em>. The primary aim is to ease inflammation and pain by improving blood circulation and relaxing the muscles. In this regard, an attempt has been made to review the <em>Ganas</em> (Group of drugs) like <em>Vednasthapana</em>, <em>Daha</em>-<em>Shamaka</em> and therapies like <em>Basti</em>, <em>Swedna</em> mentioned in Ayurvedic classical texts and scientific journals which helps in management of symptom and eliminate the root cause of diseases.</p> Tanvi Sood Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 59 64 10.47070/ijapr.v9i11.2082 Appraisal on Special Ayurvedic Dietary Formulas for Metabolic Syndrome https://ijapr.in/index.php/ijapr/article/view/2098 <p>Metabolic syndrome and related complications are a major challenge for health providers of present era. Metabolic syndrome with key characters of abdominal obesity, insulin resistance, hypertension and dyslipidemia are the outcomes of faulty diet and habits. Since there are no such pharmacological agents which can reverse this condition more importance is being given to diet and lifestyle modifications. Traditional medicinal systems like Ayurveda gives equal importance for food and nutrition in both health and diseased conditions. Concept of <em>Pathya</em> -<em>apathya </em>for each and every disease is unique to Ayurveda where the macro and micronutrient principles were selected rationally for each disease conditions. These very principles can be adopted along with dietary supplements for curbing modern lifestyle disorders, more over there is mentioning of similar conditions in classics under a board term of <em>Santharpanajanya Vikaras. </em><strong>Materials and methods- </strong>Thorough literary search done on various classical Ayurvedic texts for various diet and dietary preparations and online bases for their pharmacological properties from Ayurvedic and modern perspective and enlisted the dietary supplements. <strong>Results- </strong>Selected three major ingredients for the macro nutrient principles carbohydrate, protein and fat suggestive for MS from <em>Sthoulya Prakarana</em> and their properties are critically reviewed. <strong>Conclusion- </strong>There is enough scope of research in Ayurvedic dietary supplements for obesity and Metabolic Syndrome.</p> C S Archana V C Indulekha Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 65 69 10.47070/ijapr.v9i11.2098 Review of Jwarahara Gutika Yogas Containing Vatsanabha in Sahasrayogam https://ijapr.in/index.php/ijapr/article/view/2175 <p><em>Vatsanabha</em> is <em>Vishavarga</em> <em>dravya</em> mentioned in many of the Ayurveda Samhitas, which is commonly used in Ayurvedic medicinal preparations. It has a property of <em>Jwarahara, Amaghna, Swedajana</em> which is very useful in <em>Jwara cases. </em>The drugs like <em>Parada, Gandhaka, Hingula </em>along with <em>Vatsanabha </em>shows fast action on <em>Jwara</em>. In Ayurveda there are many formulations mentioned with <em>Jwarahara</em> properties. In this article we are studying about 17 <em>Jwarahara Gutika yogas</em> containing <em>Vatsanabha</em> which are mentioned in <em>Sahasrayogam</em>. Purpose of this study is to analyse these <em>Yoga</em> in the aspect of their ingredients, <em>Bhavana dravya, Anupana, Sevana vidhi, </em>and their role in management of <em>Jwara</em>. When we analysing each and every ingredients on these <em>Yogas </em>there are certain similarities in ingredients, <em>Bhavana dravya, Anupana </em>of these medicines. Most of these ingredients have <em>Deepana Pachana karma, Katu Thikta rasa, Ushna</em> <em>veerya, Katu vipaka </em>etc which are beneficial for<em> Samprapti vighatana </em>of<em> Jwara. </em>As <em>Sahasrayogam</em> is a compilation of popular formulations which are commonly used by ancient physicians of Kerala, it is assumed that all of this <em>Yoga </em>were once in practice. These formulations are to be kept in tablet form which is very convenient for their administration, palatability etc. But very few of them are available in market. In this current scenario of Covid pandemic Ayurveda field should rethink about these potent medicines of <em>Jwara </em>for the well being of our community, and further study and clinical trial also needed to know their action on <em>Jwara</em>.</p> KV Reshma Phalgunan Madavi Subhashchandra Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 70 78 10.47070/ijapr.v9i11.2175 A Case Study on Ayurvedic Management in PCOS https://ijapr.in/index.php/ijapr/article/view/2111 <p>Female reproductive system consists of hypothalamo-pituitary-ovarian axis and intact uterine-adnexa which maintains a complex mechanism. In human body all the systems are interrelated to function properly; any imbalance in one system may cause multisystem pathogenesis. Polycystic ovarian syndrome (PCOS) is a common endocrinopathy, which is multifactorial and polygenic condition, manifested as oligoovulation or anovulation, signs of hyperandrogenism and multiple small ovarian cysts. Signs and symptoms vary within individual’s overtime. This adversely affect the reproductive system by menstrual disorders, infertility, obesity, depression, sleep apnea, insulin resistance and in due course may result in diabetes mellitus, endometrial cancer, cardiovascular disease etc. According to Ayurveda PCOS is a disorder which involves the three <em>Doshas</em>, <em>Dhathus</em> like <em>Rasa</em>, <em>Raktha</em> and <em>Medas</em>. The <em>Srothas</em> involved in this condition are <em>Rasa</em>, <em>Rakta</em> and <em>Arthava</em> <em>vaha</em> which eventually manifests features such as <em>Anarthava</em> (amenorrhea), <em>Vandhyathwa</em>, <em>Pushpagni</em>, <em>Abeeja</em> <em>rtuchakra</em> (anovular bleeding). Here is a case report of 19 year old girl who presented with irregular menstruation, rapid weight gain and hair loss. On USG she was detected to have bilateral PCO pattern. Based on the clinical features, treatment principles adopted were <em>Aamapachana</em>, <em>Vata</em> <em>anulomana</em>, <em>Kaphapittahara</em> and <em>Arthava</em> <em>janana</em>. After 2 months of internal medications, symptoms reduced markedly and menstruation was normal. Adherence to Ayurvedic principles is found to be helpful in PCOS for a healthy and fruitful life.</p> Shahina Mole.S Ammu.K.Sasi Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 79 81 10.47070/ijapr.v9i11.2111 Nimba (Azadirachta Indica) Pratisaraneeya Teekshna Kshara: A Comprehensive Review https://ijapr.in/index.php/ijapr/article/view/2176 <p>Ayurveda promises, a disease free, happy and long life. Among the eight branches of Ayurveda<em>,</em> each branch consists of enormous knowledge from basic concepts up to critical health care strategies. <em>Shalya tantra</em> a prime branch in <em>Astanga </em>Ayurveda is the rich in many aspects of modern surgical concepts. This branch has immense potential to belt the solution of many challenging and unresolved complicated surgical ailments. <em>Acharya Sushruta</em> the pioneer in the field of surgery described four principles therapeutic types in the management of <em>Arshas</em> i.e., B<em>heshaja</em>, <em>Kshara karma</em>, <em>Agni Karma</em> and <em>Shastra Karma.&nbsp; </em>Ayurvedic approach especially <em>Kshara Karma</em> stood for better than modern therapeutic option in terms of safety, easy, low cost, devoid of post operative complications and can be done as OPD procedure with minimal set up. <em>Nimba</em> <em>pratisaraneeya kshara</em> has been mentioned throughout the classical literature for <em>Arsha</em>, described as an <em>Upakrama</em> and is substitute for surgical procedure. <em>Nimba pratisaraneeya teekshna kshara</em> which is having antibacterial, antiviral and antifungal properties and is specially told by <em>Acharya</em> <em>Sushruta</em>. It can be successfully used in the management of <em>Ardra Arshas</em> without any post operative complications. <em>Pratisaraneeya kshara</em> is external application of <em>Kshara</em> whereas internal use of <em>Kshara</em> is known as <em>Paniya kshara</em>. Acharya Dalhana the commentator of <em>Sushruta</em> explained that the substance which produces <em>Shodhana</em> of bodily <em>Dosha, Dhatu, Maladi</em> because of its <em>Ksharana</em> action is called <em>Kshara</em>. It is known as <em>Kshara</em> (alkali) also because of its corrosive nature <em>(Ksharana) Kshara</em> is having benefits like <em>Chedana, Bhedana, Lekhana, Shodhana</em> and <em>Ropana</em> properties with early hemostasis and total eradication of infection, so that it reduces recurrence, helps for the wound healing and also&nbsp; the duration of treatment is less. Though many researchers have been carried on <em>Nimba </em>till date, this review is done to highlight the significance of <em>Kshara</em> property in <em>Nimba</em> along with its therapeutic use</p> Manjunath.C.M M.N.Hiremath Raghuveer Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 82 86 10.47070/ijapr.v9i11.2176 A Case Report on Ayurvedic Management of Perimenopausal Bleeding https://ijapr.in/index.php/ijapr/article/view/2132 <p>Perimenopausal period is the transitional period where a woman passes from the reproductive to the non-reproductive stage. Abnormal uterine bleeding in the perimenopausal period accounts for 70% of all gynecological problems. Most of the abnormal uterine bleeding in this period is due to endometrial abnormalities. In Ayurveda the condition can be correlated to <em>Asrigdhara</em>. This is the case report of a 54 year aged lady who presented with complaints of excessive bleeding and frequent menstrual cycles since three months. Investigations were done to rule out malignancy. USG report showed endometrial hyperplasia of 17mm with bulky uterus. Pap smear and Colposcopy reports showed inflammatory and CIN I changes with HPV flat lesions respectively. Bleeding stopped after two weeks of internal medication. USG done after six months showed significant reduction in endometrial thickness. Pronounced changes were also seen in Pap smear and Colposcopy findings.</p> Kavitha K S Aswini Mohan L Asha Sreedhar Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 87 89 10.47070/ijapr.v9i11.2132 Balatantram - A Book Review https://ijapr.in/index.php/ijapr/article/view/2105 <p>Ayurveda the ancient Indian bioscience depicts all the aspects of healthy living. <em>Kaumarabhrithya</em> is a very important branch among the <em>Ashtangas</em> of Ayurveda. <em>Balatantram</em> is a valuable book in <em>Balachikitsa</em> written by Kalyana Vaidya in 16<sup>th</sup> Century. The work has 14 chapters, signified as <em>Patala</em> and has approximately 831 verses. Narration of <em>Balatantram</em> contains the principles and practices regarding the various aspects of diseases of children along with infertility related to males and females and <em>Vajikarana</em> <em>upayas</em>. This book is already published yet not very popular. This review would help the scientific community to understand this book in concise manner.</p> Jiji N G Braivin Camly R Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-20 2021-12-20 90 92 10.47070/ijapr.v9i11.2105 An Ayurvedic Critical Review on Nutritional Deficiency Disorders in Children https://ijapr.in/index.php/ijapr/article/view/2137 <p>Ayurveda has two basic aims i.e., first preventive aspect rather than curative method. <em>Aahara</em> (food) plays very important role to maintain health of a person as it is one of the three sub pillars (<em>Tri-upastambha)</em> of Ayurveda<em>.</em> <em>Aahara </em>is the main source of energy and nutrition, also with therapeutic value and most important during post treatment period to regain the strength of body. <em>Aahara </em>not only nourishes the body but also nurtures the mind and soul, hence it is called as <em>Poornabramha</em> and <em>Aahara-sevana</em> (eating food) considered as a ritual in Ayurveda. Nutrition is always a basic and essential part for mankind. It has also positive effect on growth and development with cognitive function in children. Various health problems can be prevented through nutritious diet.</p> <p>Malnutrition generally refers both to under nutrition and over nutrition diseases. Nutritional deficiency disorders are described in various Ayurvedic texts which can be correlated with <em>Apatarpanajanya Vyadhis</em>. Various <em>Acharya</em> of Ayurveda described diseases such as <em>Phakka, Parigarbhika, Balashosha, Karshya</em> etc in different <em>Samhitas </em>can also correlated to nutritional deficiency disorders. A critical review of these disorders provides different aspects of malnutrition and proper understanding of pathogenesis in terms of <em>Dosha - Dushya</em> which will give a valuable key for their effective management. This paper highlights the Ayurvedic review of nutritional deficiency related disorders in children</p> Singhade Sapna Raoji Lanjewar Swati Rajkumar Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-26 2021-12-26 93 96 10.47070/ijapr.v9i11.2137 Effect of Nasya Karma in the Management of Avabahuka - A Case Study https://ijapr.in/index.php/ijapr/article/view/2177 <p><em>Ayurveda</em> is the traditional medical science of India. <em>Vata </em>aggravated brings about contractions of the <em>Siras</em> (nerves) of the <em>Arm</em> and produce the disease <em>Avabahuka</em> (Frozen Shoulder) then occurs Pain &amp; loss of movement of the arm. <em>Avabahuka </em>is a disease that causes problems in daily activities of an individual like dressing, eating, personal hygiene and work. Shoulder joint is the most mobile joint in the body. Clinical presentation and pathogenesis of <em>Avabahuka</em> It Can be correlated with Frozen Shoulder<sup>. </sup>In classics, <em>Nasya </em>is indicated for <em>Avabahuka</em>. The aim of the present study was to evaluate the effectiveness of <em>Nasya karma</em> on <em>Avabahuka</em>. Method: In our <em>Panchakarma </em>OPD 55 years old male patient came with chronic pain in both shoulders joint. Patient was unable to movement both hand &amp; he was Unable to carry out daily activities. Patient was taken 15 days <em>Panchakarma </em>therapy, After <em>Snehana Nadi Swedana Nasya karma</em> was done by <em>Anu Tailam</em>. Result: After 15 days of treatment there was marked relief of the symptoms like Pain, Stiffness etc. Conclusion: The therapies were found significantly effective and clinically safe and no adverse reactions were reported during the treatment period.</p> Nupur Biswas Copyright (c) 2021 International Journal of Ayurveda and Pharma Research https://creativecommons.org/licenses/by-nc-sa/4.0 2021-12-18 2021-12-18 97 100 10.47070/ijapr.v9i11.2177