International Journal of Ayurveda and Pharma Research <div align="justify"> <p class="para1"><strong>International Journal of Ayurveda and Pharma Research (IJAPR)</strong>&nbsp;is an international peer reviewed Monthly open access Online and Print journal. The aim of the journal is to increase the impact of research in both academic and industry, with strong emphasis on quality and originality. The journal promotes to publish the articles in the field of&nbsp;<strong>Ayurveda, Siddha, Yoga, Naturopathy, Unani, Homeopathy and Allopathy</strong>&nbsp;systems of medicine and Pharmaceutical Sciences. Researchers may submit (1). Original Research Articles (2). Review articles (3). Book Reviews (4). Short Communications/ Research Letter (5). Case Report (6). Letter to the Editor/Correspondence.</p> </div> International Journal of Ayurveda and Pharma Research en-US International Journal of Ayurveda and Pharma Research 2322-0902 A Comprehensive Overview of Agni in Dyslipidemia <p>The whole philosophy of Ayurveda is based on achieving, maintaining and promoting positive health. The equilibrium of various structural and functional units of the body named as <em>Dosha, Dhatu, Mala, Agni</em> and more important the mind results in health and disequilibrium causes disease. This era is of industrialization, stress during the work, dietary habits, lack of exercise and various varieties among the daily diet results into the disturbance of <em>Agni</em> or metabolism and ultimately leads to clinical entity known as Dyslipidemia. Dyslipidemia is not a single but a range of disorders with a variety of genetic and environmental determinants. It is a condition in which the levels of lipoproteins; that is; cholesterol, triglycerides or both are altered in plasma. A cluster of other metabolic risk factors are found with the dyslipidemia including obesity, glucose intolerance, insulin resistance and hypertension. <em>Agni </em>is responsible for all the metabolic activities of body. As per modern medicine the dyslipidemia is mainly because of the disturbances in the metabolism. <em>Agni</em> is involved in the metabolism at macro and micro circulation of body on the some way or the other.</p> <p>Many theories have been put forward with many new hypotheses describing this disorder in Ayurveda as well as in modern science; still there is enough scope to work out on its aetiopathology and management aspects; as in modern science its management aspect remains symptomatic with troublesome side effects. Until pathology is clear, treatment part remains difficult. Hence the management of this disease is merely insufficient in other systems of medicine and patients are continuously looking with a hope towards Ayurveda to overcome this challenge.</p> Mayuri Shingnapurkar Kawale Meenakshi Rewdkar Kole Copyright (c) 2023 International Journal of Ayurveda and Pharma Research 2023-05-12 2023-05-12 1 8 10.47070/ijapr.v11iSuppl2.2783 Preparation and Standardization of Yogaraja Churnam <p>Therapeutics in Ayurveda is really a treasure to be explored, understand and utilized to its maximum benefit. The preparations in Ayurveda are a reflection of its personalized medicine theory. Each formulation is designed and modified in such a way that it can suit to a person's condition in every aspect.<em> Ayah paatra</em> <em>pralepanam</em> is one of the unique therapeutic methods in this science. Most of the preparations in this method is ideal for curing the hepatic pathologies. In this paper an attempt is to done to explain the preparation of one among the valued herbo mineral preparation named <em>Yogaraja Choornam.</em> The preparation of the formulation involves the identification of genuine raw materials, powdering the herbal drugs to a fine size, for mineral drugs it involves its purification, incineration, finally proper mixing and the smearing of formulation in an iron vessel. Standardization of Ayurvedic formulation is an on-going process where one needs to be keen in identifying the new scientific methods to study the fine chemical procedures and the intermediate compounds formed, but at the same time be vigilant in sticking to the classical in parameters to be followed. For the mineral drugs the<em> Bhasmas</em> produced are subjected to classical evaluation like <em>Sookshmatvam </em>(fineness<em>), Rekhapurnada, Vaaritaratvam, Uthan/unamam, Niswadu</em> etc to confirm the Ayurvedic standards of <em>Bhasmas.</em> They are also subjected for XRD, XRF, SEM and AAS estimation for identifying the crystal structure, elemental analysis and fineness and composition. For the <em>Ayaah pralipta Yogaraja Choornam the</em> pH, ash values, particle size estimation, loss on drying, water extractives values and microbial load estimation are done. The values affix the standard for the formulation. Standardization of <em>Yogaraja choorna</em> is done which creates a background for the further studies to be carried out on the formulation.</p> Raji R Nair Tara Lakshmi.S Copyright (c) 2023 International Journal of Ayurveda and Pharma Research 2023-05-12 2023-05-12 9 14 10.47070/ijapr.v11iSuppl2.2784 A Preliminary Observation Study to Evaluate Safety and Efficacy of Boheco Glide in Osteoarthritis <p>The most prevalent form of arthritis, both in established and emerging nations, is osteoarthritis. A persistent, progressive musculoskeletal disease, it causes stiffness, discomfort, and mobility impairment because of the bones rubbing against one another in the joints. With a frequency of 22% to 39% in India, it is the most prevalent form of joint illness. The two most powerful phyto-cannabinoids found in the <em>Cannabis sativa</em> plant are CBD (cannabidiol) and delta-9-tetrahydrocannabinol (THC). <em>Cannabis sativa</em> or <em>Vijaya</em> has <em>Shulahara</em> property as per Ayurveda.<em> Cannabis sativa</em>, also known as <em>Vijaya</em>, has <em>Ushna</em> properties that have the power to reduce <em>Vata dosha</em>. <em>Shleshaka Kapha</em>, which is found in the articular membrane of joints, is reduced because of excessive <em>Vata dosha</em>. Oil has a propensity to make synovial fluid, also known as <em>Shleshaka kapha</em>, more abundant in joints. As a result, reducing friction in joints also lessens discomfort and irritation. <strong>Method: </strong>A preliminary survey on 30 patients was conducted and data was collected. <strong>Results:</strong> More than 80% of patients had reduced symptoms of pain and inflammation in joints, post-application twice a day with a lasting effect of more than 3 hours. It helps in replenishing <em>Shleshaka kapha </em>present in joints.<strong> Conclusion: </strong>Glide oil was having a better result in patients having moderate to severe pain in joints.</p> Jain Harshad Patel Neeraj Kumar Jamas Jahan Peston Copyright (c) 2023 International Journal of Ayurveda and Pharma Research 2023-05-12 2023-05-12 15 21 10.47070/ijapr.v11iSuppl2.2739 The Role of Pruthkparnyadi Gana with special reference to Complications in Pregnancy <p>Pregnancy is a wonderful moment as to give birth to new live. Physiological changes during pregnancy may lead to complication of both mother and baby. Among these preeclampsia, eclampsia and epilepsy are major cause of maternal mortality in developed and developing countries causing perinatal morbidity and mortality with foetal growth retardation. In Ayurveda, complications in pregnancy are not mentioned specifically. <em>Masanumasik Paricharaya </em>for <em>Garbhini</em> (regimen for the pregnant woman) is mentioned, which helps to prevent and cure disease and maintain health of mother and foetus. Pre-eclampsia and eclampsia mostly occurs after 20 weeks of gestation. During pregnancy mostly <em>Madhura</em> (sweet) <em>Rasa</em> drugs are used while in 6<sup>th</sup> and 7<sup>th</sup> month of pregnancy<em> Acharya</em> <em>Sushruta</em> has mentioned <em>Gokshur</em> and <em>Pruthkparnyadi Gana</em> additionally. Plants reviewed showed antiepileptic, anti-hypertensive, nootropic, anti-inflammatory, anti-oxidant, rejuvenative, diuretics, and cardio protective properties, which are helpful in safe and natural management of complications in pregnancy. So there is definite role of above drugs. Hence an attempt has been made to elaborate the role of these drugs in complications during pregnancy.</p> Mandle Rita Gaurav Chaudhari Vivek Murlidhar Copyright (c) 2023 International Journal of Ayurveda and Pharma Research 2023-05-12 2023-05-12 22 32 10.47070/ijapr.v11iSuppl2.2785 A Critical Review on the Impact of Ayurvedic Dietetics (Pathya Apathya) in the Management of Dyslipidemia <p>Dyslipidemia is defined as abnormal amount of lipids in the blood. It is a metabolic disorder, manifested as increased plasma levels of total cholesterol, triglyceride or a decrease in high density lipoprotein. Dyslipidemia is the main disposing factor for the atherosclerosis, and the atherosclerosis is the main pathogenesis factor for cardiovascular disease. In Ayurvedic view, dyslipidemia can be considered similar to aggravated <em>Dusta Meda Dhatu</em> in the body which is caused due to hypofunction of <em>Medo-Dhatwagni </em>leading to <em>Medovaha Srotodusti Vikara</em>. <em>Nidanparivarjana</em> is the main treatment principle of Ayurveda.</p> <p>For dyslipidemia, diet which is <em>Laghu, Ruksha, Kaphamedohara </em>and<em> Srotoshodhana</em> property should be followed. While, <em>Guru, Snigdha, Kaphamedokara </em>and<em> Abhishyandhi</em> food should be avoided. According to <em>Bhaisjya Ratnawali</em>, <em>Pathya</em> for <em>Hridroga</em> are<em> Dadima, Shunthi, Yavani, Patol</em> etc while <em>Apathya</em> are <em>Ksheer Vikruti, Dadhi, Guru Bhojan </em>etc. Using healthy diet rich in complex carbohydrates, vegetables, and fruits seasoned with adequate quantity of spices with minimum amount of oils and fats are ideal for management and prevention of dyslipidemia. So this research article, will explain the properties of <em>Pathya</em> and <em>Apathya </em>their mode of action in prevention and management of dyslipidemia with the help of previous research work done on related <em>Pathya Apathya </em>food article.</p> Nishika Sahu Charu Bansal Saleha Zainab Copyright (c) 2023 International Journal of Ayurveda and Pharma Research 2023-05-12 2023-05-12 33 38 10.47070/ijapr.v11iSuppl2.2756 Effect of Anand Yoga in the management of Mootrashmari <p><em>Ashmari</em> is considered as <em>Mahagada</em> being difficult to cure, <em>marmaashrayi</em> and involvement of <em>Bahu dosha</em>. <em>Ashmari</em> is <em>tridoshaja</em> in origin. <em>Basti</em> is <em>vyakta stana</em> of <em>Ashmari</em> and <em>basti</em> is also a <em>pranayatana.</em> It is a fatal disease as it needs surgical intervention. On prognosis this disease is <em>kruchasaadhya</em>. Now in this era, there are many treatment modalities like Flush out Therapy and Surgical procedure are developed in this regard but failed in treating the root cause and recurrence of disease, as these procedures cannot avoid the pathogenesis behind the formation of stone results in recurrence of stone which is becoming a great problem and constant efforts are being made to evolve an effective treatment as well as prevention and recurrence of disease. It is the time for the medical science to give it’s best to treat the condition effectively. In this connection it is postulated that Anand Yoga is one of the herbal compound which is having lithotriptic action and can be used as paniya kshara and also be used at OPD level and economical also.</p> Nagesh Kumar Sharma Amit Sharma Kumari Nidhi Shree Bibhuti Copyright (c) 2023 International Journal of Ayurveda and Pharma Research 2023-05-12 2023-05-12 39 42 10.47070/ijapr.v11iSuppl2.2755 The Pharmacological Usage of Panchadeepakini Chooranam for Respiratory Ailments <p>An old Indian traditional medical practice called Siddha developed in South India. The Lord typically serves as the source of the system. It is believed that Goddess Parvathi, represented by Lord Shiva, received the Siddha system's knowledge from the Almighty, who then passed it on to Nandikeswara. Nandikeswara was appointed to set up for the framework to be spread in the midst of humankind thus, he obediently granted the information to Sage Agastya. Agastya gave all of the relevant information to his various disciples, who helped spread the system around the world. Diet and lifestyle play a significant role in both health and disease treatment, according to the Siddha medicine system. <em>Pathiyam</em> and <em>Apathiyam</em> refer to this Siddha medicine concept, which is essentially a rule-based system with a list of "dos and don'ts.” The aim of this review article is to explore the scientific literary evidence for the therapeutic usage of <em>Panchadeepakini chooranam </em>for (<strong><em>Silethuma Noi/</em></strong><em>Kaba Noi</em>) as mentioned in <em>Citta Vaittiya Tirattu</em> and to&nbsp;assign effort to entity the pharmacological activity for the curative nature of the drug. Most of the raw drugs used for the preparation of <em>Panchadeepakini chooranam</em> have bronchodilatory activity, anti-tussive activity, anti-allergic activity, immunomodulatory activity, anti-histamine activity hence justifying its usage in respiratory illness.</p> A Ragaroobine Copyright (c) 2023 International Journal of Ayurveda and Pharma Research 2023-05-12 2023-05-12 43 50 10.47070/ijapr.v11iSuppl2.2769