International Journal of Ayurveda and Pharma Research

A Case Study Highlighting the Impact of Dadhimadi Ghrut on Pandu Roga w.s.r. to Iron Deficiency Anemia

Aishwarya Pandey — 2024-10-20

Context: In India, the most common cause of anemia is a nutritional iron deficiency. The nearby term for iron deficiency anemia (IDA) in Ayurveda is Pandu Roga. Due to the high prevalence of IDA in society and the frequent side effects of oral allopathic iron preparations, Ayurvedic ghee was given in a case report of a woman suffering from IDA in order to evaluate the efficacy of Dadhimadhi Ghrut, an Ayurvedic remedy. Aim: Evaluation of role of Dadhimadhi Ghrut in haemoglobin level and iron binding capacity in a patient suffering from Pandu (IDA). Design: Case report - Clinical study. Materials and Methods: The study was conducted on a woman of IDA for a period of 12 weeks. Clinical features and hematological parameters were documented before, during and after treatment. Results: The present study shows that the trial drug Dadhimadhi Ghrut is effective to improve clinical features and hematological parameters significantly. The medicine is effective to increase the hemoglobin level g/dL (8.4 -10.1g/dL) in 6 weeks and 3.61g/dL (8.4 -12.01g/dL) in 15 weeks. No adverse effect of the trial drug was observed during the study. Conclusion: The results suggest that Dadhimadhi Ghrut is significantly effective in the management of IDA in anemic woman.

Standardization of Katakadi Eye Drop: An Ophthalmic Preparation

Gargi Verma — 2024-10-20

Ayurveda is science in which we study about not only Atura Chikitsa but also Swasthasya Swasthya Rakshana. In this study an eye drop which comes under Arka Kalpana of Bhaishajya Kalpana. This eye drop not only treats allergic conjunctivitis but also prevent healthy eye from allergy. Main symptoms present in allergic conjunctivitis are redness, itching, burning sensation etc. In Ayurveda we correlate cataract with Vataja Abhishyanda. This eye drop is made up of Kataka, Karpura and Madhu mentioned in Sharangdhar Samhita Uttarkhand as Netraprasadana has a great potential to prevent and treat conjunctivitis. Also in this study light towards the pharmaceutical preparation of Katakadi Eye Drop. Standard operating procedures to quality assurance of ingredients, and also adhering to Indian Pharmacopeia's specifications for the final product's safety and quality for ophthalmic preparation. Pre-clinical ocular toxicity investigations have demonstrated this formulation's safety for topical use.

Qualitative and Quantitative Analysis of Karunkozhi Thylam Prepared as Per Siddha Literature

Jothikaviyarasan G — 2024-10-20

The Siddha system is a traditional system of south India especially in Tamil Nadu. Thylam (medicated oil) is one of the 32 internal medicines. Karunkozhi thylam (KKT) is used to treat Vatha disease (degenerative disease). Qualitative and quantitative analysis ensures the quality and safety of drugs and minimizing contamination and adulteration risks. Weight/ml, refractive index (RI), density, iodine value (IV), acid value (AV) were analyzed as standardization parameter and GC-MS were employed to identify the active compound and test for heavy metals (lead, cadmium, mercury, arsenic), microbial contamination, test for specific pathogen (E.coli, Salmonella spp., Staphylococcus aureus, Pseudomonas aeruginosa), pesticide residue (organochlorine, organophosphorus, pyrethroids), test for Aflatoxins (B1, B2, G1, G2) were used as a safety measure. The result shows RI was 1.457, density was 1.213g/cm³, IV was 108.12g I/100g and AV was 0.86mg KOH/g. The safety parameters are within the acceptable limit. GC-MS shows the presence of oleic acid and n-hexodeconoeic acid that have anti-inflammatory activity. This study establishes a standardized protocol for KKT, ensuring quality, safety and efficacy. The findings have important implications for regulatory compliance and suggest areas for further research.

Physicochemical Analysis and Phytochemical Evaluation of Gokshuradi Churna and its Hydro-Alcoholic Extract

Somveer Singh — 2024-10-20

Drug is an essential tool of a physician included in Chatushpada. Many single as well as compound drugs are mentioned in classics in different contexts for internal as well as external use. It is always the cumulative impact of all the ingredients in the solution that plays a critical role in therapeutics, rather than the action of the individual medication. Synergistic action, combined action and toxicity neutralizing action and basic purpose are envisaged to serve drug combinations. One such important formulation prescribed in the Ashtanga Haridya Uttartantra is Gokshuradi Churna provides specifics of the drugs Gokshuradi Churna which was chosen for study. Acharya Vaghbhatta in Uttartantra listed numerous drugs that are useful in the treatment of Alpa, Dushta Retas that specifically influence the properties of Shukrajanana (spermatogenesis) and Shukra Shodhana. This formulation consists of five ingredients i.e., Gokshura (Tribulus terrestris Linn), Ikshura (Asteracantha longifolia Nees), Mash (Phaseolus mungo Linn), Atmagupta seeds (Mucuna prurita Hook) & Shatavari (Asparagus racemosus Wild). Many formulations are available in various texts under the same name Gokshuradi Churna with different ingredients and different Rogadhikara. Keeping this aim into consideration, the present study was designed to scientific evaluation of Gokshuradi Churna and its hydroalcoholic extract on different analytical and phytochemical parameters. The study includes macro and microscopic characters, powder microscopic characteristics, heavy metals analysis and High Performance Thin Layer Chromatography fingerprints (HPTLC). The information generated by this particulars study provides relevant pharmacognostical and physicochemical data needed for proper identification and authentication of Gokshuradi Churna and its hydroalacoholic extract.

A Case Report on Management of Amavata w.s.r Rheumatoid Arthritis

Kaur Daljit — 2024-10-20

Amavata is a term from Ayurveda, an ancient system of medicine from India. It describes a condition that resembles rheumatoid arthritis, where a person experiences joint pain, swelling and stiffness. The word Amavata comes from two words: “Ama” which means toxins and “Vata’’ which refers to one of the body’s fundamental energies, often associated with movements and wind. Early diagnosis and management of the disease is the only way to reduce the chances of deformities and morbidity caused by the disease. In Ayurveda a number of treatment modalities have been mentioned to treat Amavata. Panchkarma is very important and one of the eminent treatments explained in classical text. Current case study was done on female patient of 45 year with complaints of pain and inflammation in multiple joints (bilateral ankle joints, wrist joints). She was diagnosed with rheumatoid arthritis 6 year ago. In this case study patient was given Shodhana therapy with Erandmooladi Niruha Basti and Prasarini Taila Anuvasana Basti along with Shamana Chikitsa (Bhasma Vati). The patient got marked relief from this treatment.

Oil Pulling and its Effects on Oral Health-A Fact or Fad - A Systematic Review

Kumar D — 2024-10-20

Oral health serves as a gateway to general health. Dental diseases have a detrimental effect on the quality of life. A strong relationship exists between various oral and systemic diseases. Thus, prevention and timely treatment of oral diseases like dental caries and periodontal diseases have been shown to reduce the risk of systemic diseases like cardiovascular diseases and diabetes. It reminds the necessity of maintaining an optimal oral hygiene. This can be achieved by regular oral hygiene measures including some Ayurvedic techniques like Dant Dhvani (cleansing or washing the teeth), Jivha Lekhna (tongue scraping) and Kavala Gandoosha (also known as oil pulling) etc. The use of oil pulling can be frequently found in the ancient text on medicine and recent studies have shown tremendous results on the benefits of the technique. This review article provides an insight about the concept of oil pulling or oil swishing, its method of usage, its mechanism of action and its role on preventing various oral diseases. This article also throws light on the link or relationship between dental and Ayurvedic science and the wise usage of Ayurvedic preparations for the maintenance of oral health and the cure of certain oral diseases which had been proven to be effective in the long run.

Evaluating the Swedana Method for Purifying Shankha : A Scientific Approach

Kamakshi Joshi — 2024-10-20

Shodhana is the process of conversion of poisonous drugs into non-poisonous form, thereby making them suitable for internal administration to obtain the desired therapeutic benefits. Shankha is one of the rich sources of calcium of animal origin i.e., from the shell of marine creature called Turbinella pyrum, Xanthus pyrum which are generally found in the shallow ocean coast along with the several weeds and other minerals which makes it unsuitable for direct internal administration. Hence, the intermediate process i.e., Shodhana is required. There are different methods of Shodhana like Swedana (boiling), Kshalana (washing), Bharjana (frying), Nirvapana (quenching in liquid media). This paper explores the one of the methods of Shankha Shodhana which is Swedana (boiling) of Ashuddha Shankha in lemon juice for 12 hours and different physical changes that occurred in Shankha after Shodhana viz. change in the weight, colour, hardness, texture of Shankha.

Management of Grade III Internal Hemorrhoids by HAL (Haemrriodal Artery Ligation) and Tikshna Kshara Application

Mohd Zahoor Bhat — 2024-10-20

This study aims to standardize a hybrid procedure to be used in internal Hemorrhoids (Arsha) without complication of post-operative bleeding and severe pain experienced by patients in other forms of surgical interventions. Methodology: A patient diagnosed with Grade III hemorrhoids visited outpatient department and after thorough discussion, evaluation and physical/local examination was advised to undergo Tikshana Kshara therapy along with HAL for redressal of symptoms presented as bleeding per rectum. The patient was sent for routine pre surgical investigations and pre-anesthetic checkup. A surgical plan was devised for the case using Vicryl 2-0 for HAL and Tikshana Apamarga Kshara for application on pile mass. A half slit proctoscope was used for visualization of each pile mass. Suture of 8 shape was taken at the base of each pile mass for ligation with Vicryl 2-0 and Tikshana Kshara was applied after that on each pile mass for 40 sec one after the another. Khasra was washed with Nimbu Swaras to prevent Atidagdta by Kshara. There was minimal bleeding at the time of suturing and colour of the pile masses changed immediately to Pakva Jamunphala varna. A standard Kshara prepared using Apamarga, Suddha Varga and Chitraka was used for application. Patient was kept under observation for post-operative care. Efficacy was assessed after 15 days of the procedure. Results: The procedure produced encouraging results with significant reduction in size pile masses. There was no post-operative pain or constipation. There was minimum to no post-operative bleeding or stenosis. Conclusion: This hybrid combination by usage of Vicryl 2-0 and Tikshana Kshara application shows promising results in management of G-III hemorrhoids with no to minimal complication and post-operative care. Patient can immediately get back to work with some precautions.

To Evaluate Combined Efficacy of Amrutadya Guggulu and Udvartana followed by Bashpa Sweda in the Management of Sthaulya

Santosh I. Swami — 2024-10-20

Obesity (Sthaulya) is increasing at an alarming rate in developed industrialized countries which are undergoing rapid nutrition and lifestyle disorders like Diabetes mellitus (T2DM), Coronary Heart Disease (CHD), hypertension. In Ayurveda, Sthaulya (obesity) is regarded as Medoroga, a disorder of Meda Dhatu which includes fat tissue and fat metabolism. In Ayurveda Sthaulya is regarded as Medoroga. In Sthaulya Meda causes obstruction all Strotasa which leads to of Koshthasthit Saman Vayu Vriddhi, which in turn causes Jatharagnivardhana. It leads to Medadhatvagni Mandya and augmentation of Meda which results in Chalaspika, Chalaudara, Chala stana. According to WHO World Health Statistics Report 2012, globally one in 6 adults are obese and nearly 2.8 million individuals die each year due to overweight. Amrutadya Guggulu shows Rasa-Katu, Tikta, Kashaya, Guna-Laghu, Ruksha and Virya-Ushna, Vipaka-Katu, Dosha, Karma-Kapha Vatashamaka is effective in the management of Sthaulya. The ingredients of Udvartana Triphala (Kaphahara, Deepan), Musta, Darvi, Devdaru are Tikta, Kashay, Laghu, Ruksha Gunatamak having Sthaulyahara property. Bashpa Sweda given after Udvartana will make Vilayana of Vikruta meda. Due to this property, it breaks the Samprapti of Sthaulya. Hence the present attempt is done to encompass the upto date comprehensive literature to study the mode of action of Amrutadya Guggulu and Udvartna followed by Bashpa Sweda in the management of Sthaulya w.s.r. to Ayurvedic properties. Total 40 patients were enrolled in this study, significant result was seen in all subjective criteria, also 4 to 4.5kg weight loss is seen in all patients. For statistical analysis paired student ‘t’ test, Wilcoxon test were used.

Review on Cultivation Practices of Haridra (Curcuma Longa Linn.)

Pratima Dolase — 2024-10-20

Haridra, scientifically known as Curcuma longa Linn, is a significant spice and medicinal plant valued for its rhizomes, particularly for their active compound, curcumin. This article explores the cultivation practices of Haridra, emphasizing essential aspects such as soil and climate requirements, propagation methods, irrigation, pest and disease management, and post-harvest techniques. Turmeric thrives in well-drained, loamy soils with a pH between 5.0 to 7.5, and requires a warm, humid climate for optimal growth. Propagation primarily occurs through healthy rhizomes, which are planted at specific depths and spacing to maximize yield. Effective irrigation practices, complemented by balanced fertilization and integrated pest management strategies, are crucial for healthy plant development. Post-harvest practices, including proper curing and drying, are essential for maintaining quality and marketability. By implementing these best practices, farmers can enhance productivity, ensuring the sustainability and economic viability of Haridra cultivation in the face of increasing global demand as a medicinal as well spice plant.

Review on Cultivation Practices of Amla (Phyllanthus Emblica)

Rajeshri S. Khedikar — 2024-10-20

Amla has a great potential with Rasayana potential (rejuvenating) which boost our immunity and help us live longer, and helps in disease-free lives. Amla is scientifically known as Phyllanthus Emblica. Amla is much higher in vitamin C when compared with other available natural food resources, making it an exceptionally rich food. In addition, it has plenty of antioxidants, calcium, potassium, vitamin A, and other nutrients. Traditional medicine uses Amla extensively because of its many health benefits. It is thought to strengthen the immune system, facilitate better digestion, promotes healthy hair growth, and improves skin health. Three primary varieties and seven cultivated varieties exist, each with unique fruit characteristics. It is extensively utilized for pharmaceutical products as well as commercial bases. Due to its growing commercial use and increased demand cultivation of Amla through sustainable techniques is essential. Certain techniques have been developed for cultivation of Amla that provide better, higher yields in shorter span of time. This article reviews about different aspects of cultivation technique of Phyllanthus Emblica.

Management of Sandhivata with special reference to Osteoarthritis

Manikanth M H — 2024-10-20

Sandhivata is Vataja nanatmaja Vyadhi and one of the common types of Vatavyadhi. It is most commonly witnessed in elderly patient more than 50 years due to Dhatukshaya. Females are more prone to Sandhivata due to hormonal imbalance after menopause. Since it is located in Marma sthana it is Kashtasadya. In this case study Upanaha with Goduma churana, Rasna churna, Kottumchukkadu churna, and Janu Basti with Ksheerabala taila, and Vyadhishardoola guggulu is used as Shamanayoga to manage Sandhivata. As a result observed that subject had significant relief in all cardinal symptoms. In this case study Godumadi Churna is used for Upanaha, Ksheerabala Taila used for Janu basti and Vyadhishardoola Guggulu is used as Shamanayoga for the management of Janusandhigata Vata. It is observed that all the symptoms are reduced and patient feels significant relief. This study can be taken for the further study in large sample size with different variety of patient to look over the results.

Association of Deha Prakṛti (Body Constitution) with Expression of Selected Inflammatory Markers in Patients with Chronic Kidney Disease (Ckd) - Western Province, Sri Lanka

Weerasekara S — 2024-10-20

Deha prakṛti is a fundamental concept in Āyurveda, offers a promising approach to prevent and manage Chronic Kidney Disease (CKD) through an integrated perspective. While Deha prakṛti is widely recognized for its applications in predicting disease susceptibility, facilitating early detection, guiding treatment plan and influencing dietary and behavioral patterns, there is a notable gap in scientific evidence supporting its associations with various aspects of chronic disorders such as CKD. One such aspect is the immunological impairment in CKD patients, which is a significant concern that needs to be addressed immediately and no scientifically proven studies found in relation to the above in previous literature. In order to address this research gap, present study investigated the relationship between Deha prakṛti and specific inflammatory markers- namely Erythrocyte Sedimentation Rate (ESR), C- Reactive Protein (CRP), Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-α) in CKD patients, Western Province, Sri Lanka. An assessment of the association between Deha prakṛti and the expression of selected inflammatory markers in CKD patients would provide insights to successfully manage the disease by developing targeted treatment modalities focusing on inflammatory markers. The study involved 113 diagnosed CKD patients and their Deha prakṛti type was assessed using ĀyuSoft software. ESR and CRP levels were determined according to the Westergren method and CRP latex slide agglutination method respectively, while IL-6 and TNF-α levels were quantitatively measured using Enzyme Linked Immunosorbent Assay (ELISA) based on the sandwich principle. It was observed that the types of Deha prakṛti in CKD patients are significantly associated with the levels of ESR and IL- 6 indicating that the levels of ESR and IL - 6 inflammatory markers depend on the types of Deha prakṛti in CKD patients. However, it was also noticed that the types of Deha prakṛti were not significantly associated with the levels of CRP and TNF-α. This will lead the Āyurveda physicians to plan and develop specific treatment regimens with accurate drug dosage and dietary - behavioral patterns targeting the above inflammatory markers related to the Dehaprakṛti types of the CKD patients. Since it was also observed that CKD patients with Pitta and Vāta pradhāna prakṛti types are more susceptible to elevated levels of inflammatory markers, it is advisable to implement precautions during the early stages of the disease based on the specific type of Deha prakṛti in order to prevent the progression of the disease to End stage Renal Disease (ESRD).

Management of Mixed Cerebral Palsy Through Ayurveda

Pallvi Munjal — 2024-10-20

Cerebral Palsy (CP) is the most common cause of developmental and functional disabilities in children. A non-progressive neuromotor condition of posture and movement. Cerebral palsy (CP) is described as the result of improper development of injury to the brain's motor control centers. Due to its multifactorial nature and vast range of clinical symptoms, it cannot be associated with a particular Ayurvedic disease or condition. According to Vagbhaṭa it is classified in the categories of Sahaja (hereditary), Garbhaja (congenital) and Jataja (psychosomatic) disorders. There is no known "cure" for any of the several forms and subtypes of cerebral palsy. A three-year-old male child was reported to pediatric OPD of Sanjeevani Ayurveda Hospital, Dr. S. R. Rajasthan Ayurved University, Jodhpur, Rajasthan with complaints of mixed cerebral palsy. The case was taken up and aim to assess the effectiveness of the Ayurvedic management method in enhancing the child’s quality of life, improving or enhancing his functional capacity to become dependent and facilitating early rehabilitation to avoid subsequent complications.

To Assess the Efficacy of Japapatryadi Tail and Amritadi Kwath in Vicharchika (Eczema)

Megha Sharma — 2024-10-20

Skin disorders are increasingly prevalent today due to modern lifestyles and stress. Ayurveda references skin diseases primarily under the category of Kushtha, with Vicharchika (eczema) being one that is predominantly influenced by Kapha. While steroid therapies are commonly used, they can cause side effects. Therefore, exploring new topical treatments may help reduce the need for long-term steroid use. Aim: To assess the efficacy of Japapatryadi Tail local application and Amritadi Kwath in Vicharchika (eczema). Materials and Methods: This study involved an open-label clinical trial with 30 patients diagnosed with Vicharchika (eczema). The participants were treated with a topical application of Tail and an oral dosage of Kwath for 50 days. The effectiveness of the treatment was evaluated by assessing changes in the following clinical parameters before and after the intervention: Kandu (itching), Daha (burning sensation), Strava (oozing), Rukshata (dryness), Pidikotpatti (eruptions), Vaivarnyata (discoloration), Rajii (thickening of skin). Data were collected at baseline (day 0) and at the end of the treatment period. The results were analyzed using the paired ‘t’ test to determine the significance of the observed changes. Results: The topical application of Japapatryadi Tail and Amritadi Kwath was found to be highly effective in reducing the symptoms of Vicharchika (eczema). Conclusion: Japapatryadi Tail and Amritadi Kwath could be used in symptomatic relief of Vicharchika (eczema), and also repairs and enhances the damaged skin.

Daivavyapashraya Chikitsa- A Preventive Strategy to Deal Maternal Stress

Viva Myalil Vasu — 2024-10-20

Maternal stress is a potential risk factor for the onset of neurodevelopmental disorders. These days, prenatal check-ups just look at women's physical health concerns. It is crucial to remember that a variety of stress, anxiety, and depressive symptoms, such as a strained relationship with one's spouse, can also have an impact on fetal development, in addition to diagnosable illnesses. It is very well highlighted in Ayurveda with the concept of Satva Vaisheshyakara Bhaavas, which says that, the psychological makeup of the offspring is influenced by various factors, such as the mother's mental health and what she hears, while she is pregnant. Through Mantra, Mani, Mangala, Bali, Homa, Upavasa and other healing techniques, Daivavyapashraya Chikitsa is an Ayurvedic therapy method, that promotes spiritual health and helps manage mental stress by dispelling negativity and fear and replacing it with a sense of optimism and control. Additionally, this Chikitsa has several logical traits that are consistent with the Theory of Cognitive Adaptation, which holds that, people create positive delusions as a defensive mechanism to shield their mental health from outside threats. With a scientific justification, this article seeks to highlight the potential advantages of Daivavyapashraya Chikitsa in lowering maternal stress.

Effectiveness of Thantrikai Chooranam in the Treatment of Raththa Moolam (Bleeding Hemorrhoids)

Silambarasan A — 2024-10-20

Hemorrhoidal disease, a prevalent benign anorectal disorder, has a substantial influence on patients' quality of life and entails significant health and financial strains. The focus of this study is to evaluate the therapeutic value of Siddha medicine, Thantrikai Choornam, in alleviating first-degree internal hemorrhoids (Raththa Moolam). Method: A descriptive case series was carried out at the Government Siddha Medical College & Hospital in Palayamkottai, involving 20 patients (80% male, mean age 45.94±2.60 years) reported having bleeding hemorrhoids. Participants were prescribed Thantrikai Choornam (2 g, twice daily) for 24 days. Clinical symptoms such as bleeding, discomfort, constipation, and other parameters were graded both before and after treatment. Results: Substantial improvements were observed following treatment, with 75% of patients observing an overall decrease in bleeding severity from grade 3 to 0, along with a resolution of anal pain. Constipation alleviated for 85% of individuals. The average hemoglobin level raised from 11.88 to 12.25 g/dL. The statistical analysis demonstrated noteworthy reductions in the majority of complaints (p < 0.05). Conclusion: This case series illustrates that Thantrikai Choornam delivers a beneficial intervention for first-degree hemorrhoids, with considerable improvements in primary symptoms. The outcomes offer a call to further investigations into Siddha medicines role in contemporary therapeutic practices for managing hemorrhoidal disease.

An Insight into the Management of Amavata in Ayurveda

Surabhi G B — 2024-10-20

Acharya Madhavakara first identified Amavata as a separate disease in the Madhavanidana. Amavata manifests due to the consumption of Nidanas i.e., Viruddha Ahara-chesta, Mandagni, Nischalatha and immediate Vyayama after consuming Snigdha Bhojana. These factors resulting in Mandagni, which is a primary cause of Ama formation. This morbid Ama then circulates throughout the body with the vitiated Vata dosha. Ama eventually accumulates in the Sleshma sthana, results in joint pain, stiffness and ultimately causes Amavata. Comparable to rheumatoid arthritis due to similar symptoms. Rheumatoid arthritis is a chronic inflammatory disease causing symmetric peripheral polyarthritis and joint damage. Affecting 0.8-1.0% of the Indian population, rheumatoid arthritis predominantly impacts females than males. A 23-year-old female patient was admitted with the chief complaint of pain in multiple joints for 5 years. This was associated with stiffness, swelling, loss of appetite, fatigue, hard stools and a feeling of heaviness in the body. Rheumatoid arthritis is managed by DMARDs and steroids but it has adverse effects of gastritis and peptic ulcer disease as well as renal function impairment. In Ayurveda details description of management of Amavata is mentioned. Considering the signs and symptoms, the patient was treated according to the treatment principles of Amavata. Langhana, Deepana-Pachana, Valuka Sweda, Anulomana, Vaitarana Basti were administered for 25 days and oral medications for 60 days. Before starting the treatment, grading was performed based on subjective and objective criteria. After treatment, the grade was reduced. Marked improvement was observed after the treatment, which also improved the quality of life.

An Ayurvedic Approach of PCOS

Temani Rashmi — 2024-10-20

The polycystic ovary syndrome (PCOS) is an endocrine, metabolic, reproductive and dermatological disturbance affecting women and is the foremost cause anovulatory infertility. The poorly understood etiopathogenesis contributes adversely to this burning health problem of women. Maximum cardinal features of PCOS like menstrual irregularities, obesity, hirsutism, infertility, polycystic ovaries are found in Vata-Kaphaja Artava Dushti/ Granthibhoot Aartav dusthi where in other systemic involvement may be justified based on the Dosha Lakshanas of Vata and Kapha. Though the disease PCOS is not mentioned directly in any of the classics of Ayurveda, it may be understood on the basis of Dosha Dushti, involvement of Dushya, Srotas, Ama, Agni, Adhistana and Vyadhi Lakshana. Granthibhuta Artava Dushti is characterized by Dushti Lakshana of both Vata and Kapha, scanty menstrual bleeding with or without association of pain and anovulation.

A Conceptual Review on Gridhrasi w.s.r Sciatica and its Ayurvedic Management

Chauhan Neetika — 2024-10-20

Locomotor system diseases are becoming more prevalent, limiting social and professional activities. Low back pain affects a large portion of the population. The prevalence of chronic low back pain rises steadily from the third decade of life until 60 years of age, with women having a higher incidence. Gridhrasi is one of the Vataja Nanatmaja vyadhi, where dysfunction of Vata affect Gridhrasi Nadi characterized by low back pain radiating to lower limbs, stiffness and pricking type of pain. It starts from Kati-Prishta (pelvic region and lumbosacral) radiating to Jangha Paada (thigh, feet) with impairment of lifting the leg. Sciatica is the most common debilitating condition causes chronic low back ache. Radiating leg pain disabilities are observed in sciatica. Herniation of one or more lumbar intervertebral discs can causes radicular pain in the sciatic nerve distribution, which is a common and frequently incapacitating condition. This illness is thought to affect 13% to 40% of people in their lifetime. Thankfully, most instances get well on their own with basic physiotherapy and analgesic. But there’s a chance the illness will become unmanageable and persistent, with serious socioeconomic repercussions. Epidemiological factors discovered to influence the occurrence of sciatica included increasing height, age, genetic susceptibility, walking, running (if there is a history of sciatica), and specific physical jobs, such as driving. In this article, attempt has been made to review the Ayurvedic classics text and related literatures to understand the disease Gridhrasi.

Evaluating the Immunomodulatory Effect of Indukantham Gritham: An Ayurvedic Perspective

Divya K P — 2024-10-20

The basic principles of Ayurveda rely on the concept that Sharira is composed of Tridoshas (three humors), Panchamahabhuthas (five elements), Sapthadhatus (seven tissues). Any imbalance among them causes Roga. Ayurveda aims at maintaining the health of Swastha and curing the Roga in unhealthy. Classical texts of Ayurveda have defined immunity as (Vyadhikshamatwa) i.e., the ability of the body to prevent as well as arrest the progression of a Roga. In biomedical science immunology is that branch which covers the study of all aspect of immune response in all organisms. Indukantham Gritham an Ayurvedic medicine is recognized for its role in promoting health and enhancing immune function. It is composed of ghee, which is known for its rejuvenative properties, and several herbs with documented health benefits. Present article light on the concept of evaluating the immunomodulatory effect of Indukantham Gritham.

Role of Katankateriyadi Kwatha in the Management of Madhumeha (Diabetes Mellitus Type II)

Vd. Santosh I. Swami — 2024-10-20

High blood sugar levels are a hallmark of a verity of metabolic disease together referred to as Diabetes mellitus (DM). It is divided into two categories: (type 1 DM) and (type 2 DM). Type 1 diabetes results from a complete or nearly complete lack of insulin, while type 2 diabetes includes various disorders marked by differing levels of insulin resistance, impaired insulin secretion, and increased glucose production. This report presents a case of a newly diagnosed type 2 diabetes patient who received three follow-ups with Katankateriyadi Kwatha over three months (90 days). Following treatment, there were reductions in the patient's fasting blood glucose, post-prandial blood glucose levels and HbA1c levels. Further-more, no adverse effects were observed. The finding in this clinical study are encouraging and provide evidence supporting the effectiveness of Katankateriyad Kwatha in reducing type 2 diabetes mellitus in a patient.

Physiological Review of Ajeerna in the Development of Various Diseases

Sanket M. Yadav — 2024-10-20

According to World Health Organization, health is a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity. In Ayurveda also, health is nothing but harmonious balance in Doshas, Dhatus, Malas as well as Agni alongside a pleasant state of Atma, Manas and Indriya. Food and lifestyle plays important role in maintenance of health. Out of which food is most important factor for sustenance of healthy life and ensuring physiological function in human body. Food is not only essential for our physical wellbeing but it also nourishes mind. Digestion and assimilation of food is immensely important otherwise it can lead to diseases of gastrointestinal tract. Ajeerna means indigestion which is the first biomarker of malfunctioning of Jathaaragni. According to Charak Samhita, weak state of Jathaaragni (Agnimandya) is the root cause of all disease. Similarly, Madhav nidan also has mentioned that if Ajeerna is left untreated can lead to many diseases. So process of Ajeerna must be blocked by following the correct diet according to an individual's Prakriti and with proper medication treatment and lifestyle modifications. For the prevention of Ajeerna, Acharya Charak has mentioned dietary rules in the form of Ashtau ahar Vidhi Vishesh Ayatana and Acharya Shushrut has mentioned Dashvidha Ahara Vidhi vidhan. By following these guidelines and making thoughtful adjustments to diet and lifestyle, individuals can prevent the onset of Ajeerna and related diseases, ensuring the maintenance of balanced Agni and overall health.