International Journal of Ayurveda and Pharma Research 2022-05-11T00:47:35+08:00 Dr B Srinivasulu M.D (Ayu.) Open Journal Systems <div align="justify"> <p class="para1"><strong>International Journal of Ayurveda and Pharma Research (IJAPR)</strong>&nbsp;is an international peer reviewed Monthly open access Online and Print journal. The aim of the journal is to increase the impact of research in both academic and industry, with strong emphasis on quality and originality. The journal promotes to publish the articles in the field of&nbsp;<strong>Ayurveda, Siddha, Yoga, Naturopathy, Unani, Homeopathy and Allopathy</strong>&nbsp;systems of medicine and Pharmaceutical Sciences. Researchers may submit (1). Original Research Articles (2). Review articles (3). Book Reviews (4). Short Communications/ Research Letter (5). Case Report (6). Letter to the Editor/Correspondence.</p> </div> Evaluation of Nanocurcumin Mouthwash as an Adjunctive Plaque Control Agent: A Clinical Pilot Study 2022-05-05T18:35:34+08:00 Farooqui Arifa Areej Thomas Raison Shah Rucha Mavinakote Gowda Triveni <p>The use of adjunctive plaque control methods such as mouthwashes has shown to be effective in prevention of plaque accumulation. The gold standard for mouthwashes is 0.2% chlorhexidine, however, various side effects compels researchers to divert towards herbal alternatives. Curcumin has been enhanced with nanotechnology to enhance its efficacy and water solubility. The aim of study was to compare the efficacy of 0.1% nanocurcumin mouthwash to 0.2% chlorhexidine gluconate as an adjunct to scaling and root planning in localized chronic periodontitis patient. In this randomized controlled clinical study, a total of 30 patients having localized mild to moderate periodontitis were included. The study population was divided into 2 groups by randomization protocol; Group A (n=15) was given 0.1% nanocurcumin mouthwash whereas Group B (n=15) was given 0.2% CHX mouthwash. Clinical parameters including Plaque index (PI), Modified Gingival Index (mGI) being recorded at baseline, 30<sup>th</sup> day and 45<sup>th</sup> day and Sulcular Bleeding Index (SBI), Periodontal Probing Depths (PPD), Clinical attachment levels (CAL) were recorded at baseline and 45<sup>th</sup> day. Subjective criteria included taste acceptability, burning sensation and dryness whereas objective criteria including ulcer formation, tongue and teeth staining were analyzed. Statistically significant improvement was observed in all clinical parameters when compared to baseline in both groups and difference was statistically non-significant on intergroup comparison. No adverse reaction was observed in both groups in terms of subjective and objective criteria. Within the limitations, it can be concluded that nanocurcumin can be a viable alternative to chlorhexidine to formulate a mouthwash</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research A Clinical Study of Haridradi Malhar (Ointment) in the Management of Nija Vrana 2022-05-04T13:36:30+08:00 Manisha Sanjay Bang <p>The <em>Vrana </em>(ulcer) is considered the core subject of <em>Shalya</em> <em>tantra</em>. <em>Vata, Pitta</em> and <em>Kapha </em>are aggravated by their respective causative factors that get lodged in the exterior of the body to give rise to <em>Nija vrana</em> (endogenous ulcer). <em>Nija vrana</em> are frequently encountered problem in present era produced commonly by the morbid <em>Doshas</em> of the body. In the present study,&nbsp;<em>Haridradi taila</em> (ointment) is selected which is mentioned by Acharya Sushruta in the context of <em>Vrana</em>. It contains <em>Kasis, Kutaki, Jati, Haridra, Tagar, Agaru, Daruharidra, Deodaru, Priyangu </em>and<em> Lodhra</em>. These ten ingredients possess the properties of both <em>Shodhan </em>and <em>Ropan </em>(cleaning and healing). It was used topically in the type of chronic wounds daily one time for 30 days or till the healing of the wound, whichever is earlier. It is a single-blind clinical study where 20 patients were selected and divided into two groups 10 patients each. Experimental group patients wounds were treated with a dressing having <em>Haridradi </em>ointment and control group patients' wounds were treated with Framycetin ointment and dry gauze bandaging. It reduces pain, burning sensation, itching, decreases discharge, oedema and helps in gradual improvement in floor and granulation tissues as compared to control group. <em>Nija vrana</em> (chronic wounds) management with Ayurvedic remedies is one of the major areas of research, hence it can be speculated that <em>Haridradi </em>ointment possesses sufficient efficacy in <em>Vrana shodhan</em> and <em>Vrana ropan </em>(cleaning and healing of the wound) without creating any adverse effect</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Review on Wound Healing Activity of Ropana Taila 2022-05-04T13:36:26+08:00 Nidhi Shah Shuchi Mitra Usha Sharma Khemchand Sharma <p>Wound is a break in the integrity of the skin or tissue often, which may be associated with disruption of the structures and functions. Wound healing is a complex series of events that begin when an individual gets affected by a wound. It is a mechanism whereby the body attempts to re-establish the integrity of the injured part. In modern biomedical sciences, research on wound healing agents is one of the developing areas. Natural compounds are used in skin wound care from many years due to their therapeutic activities, including anti-inflammatory, antimicrobial, and cell-stimulating properties. Various herbs, oils and natural resources have been described in Ayurveda with wound healing properties. Acharya Sushruta has explained many drugs and formulations for the treatment of <em>Vrana</em> (wound). One such formulation named <em>Ropana Taila</em> has been described in <em>Sushsruta Samhita</em> for Wound healing. The present review article is undertaken to discuss about the wound healing activity of <em>Ropana Taila</em></p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research A Case Study: Management of Ankylosing Spondylitis in Ayurveda 2022-05-04T00:32:11+08:00 Sumit Kumar Ragini Kumari Pankaj Kumar Vijay Bahadur Singh <p>Ankylosing spondylitis (AS) is chronic inflammatory disorders of unknown cause that primarily affects the axial skeleton (Predominantly sacroiliac joints and spine) peripheral joints and of extra articular structures may also be involved in an asymmetrical pattern. The disease usually begins in the second or third decade; the male to female prevalence is approximately 3:1. Patients having AS, more than 95% of them are positive HLA-B27. Use of NSAIDS are the first line of management and they effectively relieve the symptoms. Few Ayurvedic medicines found to be effective in the management of AS. Here, a case study of AS managed by Ayurvedic treatment approaches is presented. A patient 21yrs male came to OPD of<em> Kayachikitsa</em> i.e., Room No. 9 of GACH, Patna. He complaint of pain in B/L ankle left&gt;right, also B/L knee joint pain as well as low back pain for 6 months. He was diagnosed on the basis of its signs and symptoms of AS with HLAB27 positive. He was managed by Ayurvedic medicines like<em> Panchatikta Ghruta Gugglu, Ekangveer ras, Tab. Shallaki, Cap. Stresscom, Jrumax </em>oil<em>, Vaishwanar churna, Laxarid</em> for 7 months and relief in his signs and symptoms.</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research A Case Study Over Pityriasis Rubra Pilaris Through Ayurvedic Management 2022-05-04T00:31:58+08:00 Vivek Raghuwanshi Mohammad Aamir Megha Murali Vijay Bahadur Singh <p>Skin disorder are common manifestation in present era and more so frequent in elder age. The patient of skin disease is more prone to experience physical, emotional and socio-economic embarrassment in the society due to disfigured appearance. Normally 10-15% of the general practitioners encounter with skin disorder in there day to day practice. <em>Vaipadeeka</em> and <em>Charma kustha</em> is a type of <em>Kshudra kustha</em> occurring mainly due to the imbalance of <em>Vata</em> and <em>Kapha doshas</em> resembling the Pityriasis Rubra Pilaris in its clinical manifestation. Pityriasis rubra pilaris is rare chronic disorder that causes hyper keratotic yellowing of the skin including trunk, extremities and particularly palm and sole. The palm and sole become thickened smooth and yellow fissure are common. Systemic corticosteroid, oral retinoid, immunosuppressive such as cyclosporine are the mainstay of treatment of Pityriasis rubra pilaris. The modern treatment modalities are not devoid from grave complication mainly in long term use. Owning these reasons, there is need for treatment having good efficacy and no toxic profile. So this case study was conducted considered ptyriasis rubra pilaris as <em>Charma kustha</em> and <em>Vaipadeeka</em>. Ayurvedic management was planned accordingly. Good result was witness by<em> Virechan</em> and <em>shaman.</em></p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Effect of Paribhadra Paneeyakshara in Mutraghata Caused by Benign Prostatic Hyperplasia- A Case Report 2022-05-04T00:31:23+08:00 M S Devinandini C Suresh Kumar Sreejith Satheesan <p>Benign Prostatic Hyperplasia is a troublesome disease that bothers the population of ageing men by decreasing their quality of life. It is an abnormal growth involving the submucosal glands of prostate. The disease interferes with the normal daily activities and sleep pattern and hence is a matter of concern to the medical field. The symptoms of Benign Prostatic Hyperplasia closely coincide with the symptoms of <em>Mutraghata </em>(urinary obstruction) explained in Ayurveda. When taking the obstructive pathology into consideration, <em>Paneeyakshara Prayoga </em>(alkali for internal administration) is classically mentioned as a treatment option. This work is a case study on the effect of <em>Paneeyakshara</em> prepared out of <em>Paribhadra </em>(<em>Erythrina indica</em>) which is a drug possessing <em>Vatakaphahara </em>(alleviate <em>Vata</em> and <em>Kapha</em> <em>Dosha</em>) and <em>Shophahara</em> <em>Karma </em>(pacify inflammatory swellings) in <em>Mutraghata</em> caused by Benign Prostatic Hyperplasia. A 66-year-old male who presented with the signs and symptoms of Benign Prostatic Hyperplasia was administered with 500 mg of <em>Paribhadra Paneeyakshara</em> with 1 gram of <em>Guda </em>(jaggery)<em>,</em> morning and evening, half an hour before food for a period of 45 days. Assessment was done before and after treatment based on the IPSS (International Prostate Symptom Score) of the American Urological Association and the Ultrasound abdomen findings. The post- interventional assessment showed a lowered IPS Score and reduced USG parameters indicating the efficacy of <em>Paribhadra Paneeyakshara</em> in reducing <em>Mutraghata</em> caused by Benign Prostatic Hyperplasia.</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Ayurvedic Management of Moderate Depressive Disorder- A Case Report 2022-05-04T00:31:40+08:00 Thasni M Jithesh M Brinu J A <p>Depressive disorders are highly prevalent mental disorders characterized by sadness, loss of interest or pleasure, feelings of guilt or low self-esteem, disturbed sleep or appetite, feelings of tiredness and poor concentration. About 300 million people are estimated to suffer from depression at a global level and in India the figures approximate to about 45.7 million. As per WHO, depression will be the leading cause of burden of disease by 2030 and the prevalence, incidence, and the morbidity risk of depression appears to be more in females than males.</p> <p>A 42-year-old lady presented with primary concerns of increased thoughts, decreased sleep, discomfort in stomach, abdominal distension, increased fatigue, decreased appetite and increased tension. Detailed interview with her husband and parents revealed that she had increased thoughts, slowness in performing activities, inability to do day to day works, reduced memory and concentration, increased anger towards her husband, mother and daughter, reluctance to have food and reduced social mingling. Based on the observations made in the level of affective and behavioural domains, diagnosis of depressive disorder - current episode moderate was eventually done as per the diagnostic criteria mentioned in International Classification of Disease 10.</p> <p>In Ayurveda, the condition was diagnosed as <em>Kaphaja Unmada</em> based on the typical symptoms. The treatment protocol including <em>Snehapana</em>, <em>Vamana</em>, <em>Virechana</em> and <em>Vasthi</em> was administered. The mental status of the patient was also addressed during the treatment period and <em>Satvavajaya</em> measures including individual and family counseling methods were administered. There was significant improvement in the Becks Depression Inventory score and Q – LES – Q – SF questionnaire after the intervention.</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research A Review on Kadara and its Multi Modal Treatment Approach with specific reference to Agnikarma 2022-05-04T00:32:04+08:00 Mayookha Madhusudanan Anita Patel <p>Mankind suffers from a lot of conditions which, on the outlook seem very trivial in comparison to the actual suffering arising out of the condition. <em>Kadara </em>is one such condition, which comes under the umbrella of <em>Kshudra rogas</em>. It is a condition with a simple pathology but causing intense suffering to the patient. <em>Kadara </em>can be correlated to Helomas or foot corns. Foot corns have a simple etiopatholgy but most often, difficult to attain a complete cure. Various treatment modalities available presently for the management of corn include the use of salicylic acid paints, cryosurgery, surgical removal of corn, etc. Recurrence is a common issue in almost all the said modalities. <em>Agnikarma </em>is the classical line of treatment mentioned for <em>Kadara</em>. The present article is a review of the available research works in Ayurveda, taken up in the management of <em>Kadara</em>. Majority of the works available have taken <em>Agnikarma </em>(thermal cauterisation) using various <em>Upakaranas </em>(materials) for treatment, with few other works having other modalities like <em>Lepana </em>(paste application), <em>Chedana </em>(excision) &amp; <em>Kshara karma </em>(application of alkali).</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Ayurvedic Management of Cholelithiasis - A Case Study 2022-05-04T00:32:20+08:00 Sowmya.H Sreenidhi G S Pooja.B A <p>Cholelithiasis (gallstone formation) is a common Gastrointestinal disorder. The disease Cholelithiasis has not been described directly in Ayurvedic classics. The word <em>Ashmari</em> is described only in the context of <em>Ashmari</em> (urinary calculi). Surgery is the most common form of treatment for gall stones, however the fact that surgically removing gallstones requires the removal of an entire organ has led to a growing interest in non-surgical treatment. But so far as the medical management of gall stone is concerned, it is not up to the mark in allopathic system. Hence our article is a step in the direction of making an availability of a safe and effective non-surgical management of Cholelithiasis. A 35-year-old female patient reported to OPD Bangalore, with the complaints of severe pain abdomen, anorexia, distension of abdomen and vomiting. The patient was diagnosed as cholelithiasis with physical symptoms and with the help of all investigation. Oral medications like <em>Arogyavardini vati, Varunadi Kashaya, Yavakshara</em> and <em>Katuki Churna</em> was administered to the patient for 1 month and follow up was done after 3 months of treatment, a significant response was observed over clinical symptoms and USG reports</p> 2022-04-29T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Integrative Approach in the Management of Janusandhivata w.s.r. to Osteoarthritis 2022-05-04T00:31:36+08:00 Pushpendra Kumar Kiran M. Shah Rakesh R. Tiwari <p><em>Janusandhivata </em>is a <em>Vataj </em>disorder in which <em>Vata </em>resides in <em>Janu sandhi (Vimarga</em> <em>gaman)</em> and produces various signs and symptoms according to its <em>Gunas</em>. In modern sciences <em>Janusandhivata</em> is correlated with osteoarthritis. In the present study integrative measures like allopathy medicines, Ayurvedic medicines and <em>Karmas</em>, yoga, naturopathy and exercises are studied for the effective relief of symptoms of <em>Janu sandhigata vata </em>i.e., OA. Integrative measures are studied to provide effective and fast relief to the patient. Modern treatment provides instant relief while on the other hand Ayurveda heals by curing the disease from root and is considered<em> Apunarbhav chikitsa</em> which means it prevents recurrence of the disease. Other measures aid in achieving the ultimate goal of cure from the disease.</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Ayurvedic Perspective of Polycystic Ovarian Syndrome 2022-05-04T00:31:26+08:00 Athira Raj Asha S T Shiny S Raj <p>Polycystic Ovarian Syndrome is the leading cause of female infertility in the present scenario. It is one of the important reproductive endocrine disorders in the world. The various conditions associated with PCOS show similarities with <em>Gulma, Prameha, Sthoulya</em>, etc. <em>Pushpagni Jaataharini</em> mentioned in&nbsp;<em>Kasyapa Samhita</em>&nbsp;bears some similarities with clinical presentations of this disease.&nbsp;<em>Nashtarthava</em>, <em>Arthavakshaya, and Vandhya yoni Vyapath</em>&nbsp;mentioned in&nbsp;<em>Susrutha Samhita</em>&nbsp;can also be taken into account.&nbsp;</p> <p>As PCOS is a metabolic disorder, there is impairment of the function of&nbsp;<em>Agni&nbsp;</em>at various levels. The disease can be considered as a&nbsp;<em>Bahudoshavastha</em>. It begins as&nbsp;a <em>Vata</em>&nbsp;imbalance, which pushes&nbsp;<em>Kapha</em> and <em>Pitta</em>&nbsp;out of balance in the&nbsp;<em>Arthavavaha Srothas</em>.<em> Samsodhanam</em>, use of&nbsp;<em>Agneya Dravyas,&nbsp;</em>use of&nbsp;<em>Swayoni Vardhana dravyas, </em>and&nbsp;avoidance of etiological factors is the main treatment principle.</p> <p><em>Ayurvedic&nbsp;</em>classical textbooks along with available modern literature were referred to make a clear understanding of the concept of Polycystic Ovarian Syndrome. The clinical symptoms of Polycystic Ovarian Syndrome like amenorrhea and hyperprolactinemia are seen in&nbsp;<em>Rakthagulma.&nbsp;</em>The clinical manifestation and pathology of the disease are very close to that of<em>&nbsp;Prameha</em>.<em>&nbsp;Nashtarthava</em>&nbsp;explained by&nbsp;<em>Acharya Susrutha </em>mentions that due to&nbsp;<em>Vatha Kapha Avarana, Arthavanasha&nbsp;</em>occurs in females. This can be correlated with amenorrhoea associated with Polycystic Ovarian Syndrome. In&nbsp;<em>Vandhya yonivyapath</em>, arthava is destroyed. This can be considered secondary amenorrhoea or anovulation which ultimately causes the inability to conceive a child.</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Role of Climate on Human - Concept of Ayurveda 2022-05-04T00:31:54+08:00 Chiranjit Biswas Supriyo Chaudhuri Tapan Ghosh <p>Dual concept has been recognized in appreciation of <em>Kaala</em> or time employing the scholars of Ayurveda. <em>Saambatsara</em> or <em>Nityaga</em> <em>Kaala</em> denotes the year and climate changes throughout the year and <em>Atura</em> <em>Avastha</em> or <em>Avastika</em> <em>Kaala</em> stands for the health repute along with ailment prevalence and their control about the weather changes. The weather change can steer the earth’s biological structures. Developing countries with restricted assets are expected to face a host of health consequences because of weather change, along with vector-borne and water-borne diseases. The distribution of infectious ailment includes complex social and demographic factors. Global climate change is a phenomenon this is now taken into consideration strongly associated with health and hazards. The outcomes of climate change on exposed biological incidences, in addition to societies prone to expose with disease, are a challenge for the complete scientific community. Rising temperatures, warm waves, floods, tornadoes, hurricanes, droughts, fires, lack of forest, and glaciers, in conjunction with the disappearance of rivers and desertification, can directly and circuitously concern with human pathologies which can be physical and mental.</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research A Comprehensive Overview on Pathogenesis and Management of Osteoarthritis vis-a-vis Sandhigatavāta 2022-05-04T00:31:33+08:00 Rashmi Kathait Ajai Kumar Pandey <p>The most common joint condition encountered in clinical practice is osteoarthritis (OA) of the knee, which is a primary source of impairment in the elderly. It is a multifactorial chronic degenerative condition characterised by loss of articular cartilage, enlargement of bone at the borders, subchondral sclerosis, and a variety of biochemical and morphological changes to the synovial membrane and joint capsule. OA clinically similar to <em>Sandhigatavāta </em>of Ayurveda is one of the eighty types of <em>Nānātmaja</em> <em>Vātavyādhi</em>. The aetiopathogenesis, symptoms, and treatment of <em>Sandhigatavāta </em>found in a very concise format in classical texts. The authors have tried to put an emphasis on OA related to its prevalence, aetiology and pathogenesis based on <em>Sadkriyākāla </em>along with management by incorporating the knowledge of literary and data base resources in order to establish a guideline for the rational use of treatment modalities. The present approach may be useful for clinicians and researchers to plan appropriate strategy of management and research in the field of OA</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research A Brief Review on Tejovati (Zanthoxyllum Armatum.Dc.) in Vedas and Samhita: An Ethnomedicinally Rich Plant 2022-05-04T00:31:48+08:00 Deeksha D.C Singh Kiran Vashisht Rishi Arya <p>Medicinal plants are considered as a rich resources of ingredients which can be used in drug development either pharmacopoeial, non- pharmacopoeial or synthetic drugs. A part from that, these plants play a critical role in the development of human cultures around the world. Traditional Indian medicine (Ayurveda) is becoming increasingly popular, with many chronic conditions responding to it well. Most patients begin to take conventional medications as soon as their diagnoses are made, so Ayurvedic treatments are usually undergone alongside and/or after conventional medical approaches.&nbsp;WHO (World Health Organization) estimated that 80 percent of people worldwide rely on herbal medicines for some aspect of their primary health care needs. According to WHO, around 21,000 plant species have the potential for being used as medicinal plants. Elaborate description of the plant and its therapeutic action are explained by our <em>Acharyas in Vedas, Puranas, </em>and<em> Samhitas</em> and in the later <em>Nighantus. Tejovati</em> is such a drug which is widely available and is having many mentioning in the classics for its effectiveness in many diseases. <em>Tejovati</em> does not have any controversies in any of the literatures or classics regarding its identification or usage. The current article is to highlight the importance of drug and references has been collected from <em>Vedas, Puranas, Samhita kala, Nighantu kala</em>. Synonyms, <em>Gana Varga</em>, Vernacular names etc has been collected and arranged systematically.</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Ayurvedic Approach and Updates Related to Sveda and Svedavaha Srotasa 2022-05-04T00:31:45+08:00 Ambre Manali Jamdade Yogita More Sangeeta Phadke Chinmay Divyashree K S <p>Knowledge of Ayurveda is based on specific fundamental principles. <em>Dosha, Dhatu, Mala</em>, <em>Srotasa</em> are some among them. <em>Malas</em> are the waste products which primarily generate after digestion of food. While <em>Srotasa</em> are the channels or pathways in the human body which carries <em>Dosha, Dhatu, Mala</em> and <em>Mana. Sveda</em> (sweat) is one of the waste product which forms after digestion of food or in the process of metabolism of adipose tissue. Formation, transportation and elimination of <em>Sveda</em> is carried out by <em>Sveadavaha Srotasa</em> and it helps to regulate body temperature, maintain skin moisture and excrete toxic substance from body. Detail description of concept <em>Sveda, Svedavaha Srotasa,</em> its normal mechanism, importance in manifestation of various diseases and its application in treatment is described in Ayurvedic texts. Thinking of this fact, for better acknowledgment of these concepts and its role in the practice this comprehensive review has been done.</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Moringa oleifera Lam.: A Valuable Medicinal Plant, Boon of Nature 2022-05-04T00:31:51+08:00 Pradeep Soni Man Mohan Sharma <p><em>Moringa oleifera </em>Lam., is often referred to as “The Miracle Tree” due to its highly utility and it is said that every part of this tree have beneficial properties that can serve humanity. <em>Moringa oleifera </em>Lam., is native to the Indian sub-continent and naturalized in tropical and sub tropical areas around the world. It is very important and highly valuable medicinal plant. It has impressive range of different pharmacological action of various parts of this plant such as leaves, roots, seeds, bark, pods, flowers shows anti-bacterial, anti-inflammatory, anti-fungal, antispasmodic, antipyretic, hypotensive, cholesterol lowering, anti-diabetic, anti-biotic etc. activity. Different parts of this plant contain a unique combination of important nutritional minerals, vitamins, amino acids, ß-carotene, and various phenolics. It is widely used for medicinal and therapeutically with its high nutritional value in the indigenous system of medicine. The aim of present review study is to explore the importance of <em>Moringa oleifera </em>Lam., to reveal the nutritional and medicinal properties of this plant and summarize scientific evidence of pharmacological properties that supports the value and multifunctional uses.</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Pathya and Apathya- An Ayurvedic Framework of Wholesome and Unwholesome Diet, Behavioral and Mental Health Regime for Sthaulya- A Narrative Review 2022-05-04T00:31:21+08:00 Amulya Murthy Aku Ashok Patil Mukund Sabnis <p>The advancement of industrialization and communications has made man more sensitive and critical, resulting in a variety of health issues. Sedentary lifestyles are becoming more common as a result of the progress of industrialization and communication, resulting in chronic non-communicable diseases such as diabetes, hypertension, cancer, ischemic heart disease, cerebro-vascular accidents, atherosclerosis, varicose veins, and so on. Obesity is a risk factor for several diseases, thus preventing it will reduce the likelihood of developing them. Obesity, like other disorders, is a complex disorder caused by a combination of factors such as food, physical activity, mental health, and overall lifestyle. In Ayurveda, <em>Sthaulya</em> is the closest clinical entity for obesity. <em>Sthoulya's</em> causality is described in the <em>Asta-Nindita-Purusha</em> chapter. The etiopathogenesis of obesity is caused by an excessive intake of calories combined with a decrease in expenditure. A key weight-loss approach that can be used anywhere to reduce energy density. In Ayurveda, <em>Pathya</em> and <em>Apathya</em> are given specific attention in terms of <em>Ahara, Vihara</em>, and <em>Manasika</em> Entities, so that the ailment can be treated holistically. When these guidelines are followed, the treatment yields a better result in the treatment of the condition. This article attempts to review the pathya and apathy of obesity, as well as discuss the possible causes.</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Critical Study on Role of Nidan in Causation of Disease w.s.r. to Pandu 2022-05-04T00:31:30+08:00 Sukalyan Ray Saswati Debnath Bijita Majumder <p>In the genesis of a disease, <em>Nidan</em> or <em>Hetu </em>(causative factors) play the most crucial role. When vitiated <em>Doshas</em> afflict <em>Dhatus</em>- this conglomeration leads to a state of <em>Vikriti</em> (disequilibrium) in our body which further leads to genesis of one or more disease. In respect of any disease, the role of <em>Hetu</em> can be divided in to three pathways- <em>Dosha Prakopan</em> (vitiation of <em>Doshas</em> by <em>Hetu</em>), <em>Kha Vaigunya</em> (impairment of channels by <em>Hetu</em>) and <em>Dhatu Dusti</em> (vitiation of <em>Dhatus</em> by <em>Hetu</em>). The role of any causative factor in relation with genesis of a particular disease can be viewed in respect with any of these three pathways. In this article, the authors have made an effort to explain the role of <em>Hetu</em> in light of above mentioned concept. To understand it better, we have taken an example of <em>Pandu.</em> <em>Pandu </em>is a disease which has been described with great importance in all major and minor texts of <em>Ayurveda</em>. It is caused by vitiation of <em>Pitta Dosha</em>, mainly <em>Sadhak Pitta</em> and affliction of mainly <em>Rakta Dhatu</em>. The role of each and every <em>Hetu</em> in genesis of <em>Pandu</em> has been explained through their role in <em>Dosha Prakopana</em> (vitiation of <em>Pitta Dosha</em>), <em>Dhatu Dusti (Rakta Dusti</em>) and <em>Kha Vaigunya</em> (impairment of channels).</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Effect of Pathyadi Churna with Masthu in Amajirna w.s.r to Dyspepsia- A Case Study 2022-05-04T00:31:18+08:00 Nikhil Neelakandhan.E.U Shailesh Deshpande <p><em>Amajirna </em>is a common clinical condition that has symptoms such as - <em>Yadhabhukta Avidagdha Udgara, Praseka, Utkleda, Gatra Gaurava, Akshikoota sotha</em>. As per classics, the treatment of <em>Amajirna </em>includes <em>Dipana </em>and <em>Pachana</em>. <em>Amajirna </em>has resemblance with dyspepsia. Dyspepsia or indigestion is a common gastro-intestinal disorder with symptoms like nausea, bloating, early satiety, post prandial fullness, abdominal discomfort etc. There are various causes for the occurrence of dyspepsia including micro-organisms. The present case report is of a 41 years old male with onset of symptoms such as nausea, bloating, abdominal discomfort, early satiety, <em>Yadhabhukta Avidagdha Udgara </em>(burping with the same taste of food consumed)<em>,</em><em> Praseka </em>(excess salivation) and<em> Utkleda </em>(nausea) since one or two weeks in every month for the last 6 months. He was taking antacids while coming to the OPD, and got temporary relief. Gradually, even after taking his normal diet, the symptoms started to re-occur and effect of his medications lasted for only a few weeks. The patient was given <em>Pathyadi Churna </em>with <em>Masthu </em>as <em>Anupana </em>for 7 days. It was observed after the completion of treatment that all the symptoms disappeared after 7 days. Also, no reoccurrence for the next 4 months. This shows the <em>Pathyadi Churna </em>with <em>Masthu </em>has a significant effect in relieving the symptoms of dyspepsia/<em>Amajirna</em>.</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Bhagandara: A Review Article on Types of Bhagandara and its Management 2022-05-04T00:32:15+08:00 Rabiya Shaikh Maitree Patel <p>Ayurveda is an eternal branch considered as the science of life. Its prime motto is maintaining the health of healthy individual first and then curing the disease, which promotes a disease free, healthy life span. Ayurveda is an abundant ocean full of knowledge consisting of eight superior branches. Amongst them <em>Shalya Tantra</em> is the prime branch rich in surgical concept. History reveals that the period of <em>Acharya</em> <em>Sushrut</em> was the golden era of surgery where various surgical procedures were performed. More over in regards of anorectal and perineal surgery,<em> Acharya</em> has expounded much, with an approach of emphasise both surgical and Para surgical measures.</p> <p><em>Bhagandara</em> can be screened in ancient Ayurvedic texts and varying systematic, scientific detailed descriptions are found. It is the common ano-rectal disease prevalent in the population worldwide. Because of its tedious nature of healing <em>Bhagandara</em> is considered difficult to be cured also it is found to be one amongst the <em>Ashta Mahagada</em>, where <em>Acharya</em> has explained the limitation of the treatment by considering it as <em>Duschikitsya Vyadhi. </em>Hence this article has emphasized on the available discretion on various types of<em> Bhagandara </em>and its management.</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Need of Redefining Rasa-Dosha Dynamics - A Cross Sectional Study 2022-05-04T00:32:01+08:00 Syamily P Vinodkumar M V <p>There are standard descriptions on the relationship between <em>Doshas</em> and <em>Rasa</em> in Ayurveda textbooks. Particular <em>Rasas</em> increase/decrease respective <em>Doshas</em>, so that <em>Rasas</em> become causes of diseases through excess usage. In the other side they classify <em>Doshas</em> having opposite characters. Even when the standard <em>Rasa dosha</em> relationship prevails, in practice it is often observed that such relations are surmounted. Here is an effort to explore such phenomenon. Methodology: 1. Survey was conducted among practitioners with a structured semi validated questionnaire to collect ideas regarding most repeated <em>Dosha</em> in diseases reported at general clinics and to enlist most frequently used <em>Kashaya yogas </em>in general practice. 2. Findings were tabulated. 3. Most frequently used <em>Kashaya yogas </em>were analysed for <em>Rasas</em> of their ingredients and <em>rasa </em>profiles of the formulations were prepared. Results: From the survey it was found that most repeated <em>Doshas</em> among diseases is <em>Vata</em>. Among the most frequently used <em>Kashayas </em>majority belong to <em>Vatahara</em> group. But from the <em>Rasa</em> profiles prepared it was found that most of the ingredients belong to<em> Tikta-kashaya rasa</em>. This finding is contradicted with the conventional <em>Rasa- dosha</em> relationship. Because <em>Tikta-kashaya rasas</em> usually increase <em>Vata</em>. Conclusion: Even though <em>Rasa dosha</em> relationship is vital in Ayurveda, in practice some of the rules are violated.</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Karshya -A Critical Review on Nutritional Deficiency as per Ayurveda 2022-05-04T00:31:14+08:00 Lokhande Ketaki Sachchidanand Khatun Hazera <p>Ayurveda emphasize prevention over cure. A balanced diet with proper dietetic rule can help avoid a lot of common health concerns. The source of life for all living beings is food, growth, strength, intelligence, satisfaction, all are established in food. Food is significant as a nutritional source, as well as having therapeutic value, and it plays an important part in regaining strength lost due to the disease's detrimental effects throughout the post-treatment phase and also excess exercise, or addiction too. Ayurveda classic haphazardly explain nutritional issues. Each and every disease is due to faulty <em>Ahara</em> and <em>Vihara</em>. <em>Ahara</em> <em>vidhi</em> is equally important to get optimum benefits from consumed food. Childhood malnutrition is thought to be the cause of 35% of all fatalities in children under the age of five, as well as 21% of total worldwide disability-adjusted life years lost in children. <em>Karshya</em> not only concerns with weight loss, but also compares with malnutrition-like disorders. In Ayurveda, <em>Karshya</em> is a disease as well as cause, prodromal symptoms, feature of different diseases and bad prognostic sign. <em>Karsha</em> is also a physiological in <em>Vataja</em> <em>prakriti</em> individual. This illness is linked to growth and development issues in children and adolescence group. In adults, malnutrition results in weakness, fatigue, low immune response, protein, vitamin, minerals, fats deficiencies, and more prone to degenerative diseases. The aim of this review article is highlighted the Ayurvedic perspective on <em>Karsha</em> in term of malnutrition. All material for this article is collected from classical Ayurvedic texts. Understanding the cause and pathophysiology and accurate treatment as per Ayurved classics all are discussed here elaborately</p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research Effect of Jambira Pinda Sweda in the Management of Avabahuka 2022-05-11T00:47:35+08:00 Bidhan Roy <p>Ayurveda is boon for mankind. <em>Panchakarma</em> is the most important part of Ayurveda to uproot the disease as well as achieving the perfect balance of vitiated <em>Doshas, Dhatus</em> and <em>Agni</em>. <em>Avabahuka</em> is a disease that affects the day to day activities like cooking, dressing, bathing, eating etc. Shoulder pain is a common clinical symptom of <em>Avabahuka</em>. The symptom of<em> Avabahuka</em> may be correlated with frozen shoulder because symptoms as well as pathogenesis are more or less similar to <em>Avabahuka</em>. Acharya Vangasena had mentioned <em>Swedana Karma</em> for <em>Avabahuka.</em> Aim: To evaluate the effectiveness of <em>Jambira Pinda Sweda</em> in the management of <em>Avabahuka.</em> Method: In our Panchakarma OPD 56 years old female patient came with complain of pain in the right shoulder joint and unable to perform her normal daily activities. Patient was admitted to the Panchakrma IPD of R.A.M&amp;H and she had been treated with <em>Jambira Pinda Sweda</em> for 15 days. Result: After taking <em>Panchakarma</em> therapy, patient showed marked improvement of the symptoms like <em>Shula</em> (Pain), <em>Sthambha</em> (Stiffness) etc. Conclusion: It was found that <em>Jambira Pinda Sweda</em> had significant role in the management of <em>Avabahuka.</em></p> 2022-04-30T00:00:00+08:00 Copyright (c) 2022 International Journal of Ayurveda and Pharma Research