@article{Divyapriya_Veeresh_C.Yavagal_2016, title={EVALUATION OF ANTIBACTERIAL EFFICACY OF CHIA (SALVIA HISPANICA) SEEDS EXTRACT AGAINST PORPHYROMONAS GINGIVALIS, FUSOBACTERIUM NUCLEATUM AND AGGREGATIBACTER ACTINOMYCETEMCOMITANS-AN IN-VITRO STUDY}, volume={4}, url={https://ijapr.in/index.php/ijapr/article/view/325}, abstractNote={<p><strong>Background:</strong> <em>Chia</em> (<em>Salvia hispanica</em> L.) seeds are used widely because of its nutritional value, antioxidant and antibacterial activity against various microorganisms but there are no studies that relate the antibacterial activity of <em>Chia</em> seeds against periodontal pathogens. Hence, this study aimed to determine the antimicrobial activity of <em>Chia</em> seeds extract on Porphyromonas gingivalis, Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans. <strong>Materials and Methods: </strong>Extract of <em>Chia</em> seeds in ethanol and distilled water were obtained by cold maceration. The crude residue was obtained by evaporation at room temperature. The antimicrobial efficacy of <em>Chia</em> seeds in all extracts were assessed against oral microorganisms by finding out zone of inhibition and minimal inhibitory concentration. <strong>Results</strong>: <em>Chia</em> seeds (<em>Salvia hispanica</em>) in ethanol and distilled water were found to be effective against A.actinomycetamcmitans, P.gingivalis and F.nucleatum by highest zone of inhibition being 18mm for aqueous extract of <em>Chia</em> seeds against A.actinomycetamcomitans. Minimum inhibitory concentration for aqueous extract of <em>Chia</em> seeds for A.actinomycetamcomitans and P.gingivalis was established at 50% and for F.nucleatum at 12.5%.The minimum inhibitory concentration of the ethanolic extract of <em>Chia</em> seeds for A.actinomycetamcomitans, P.gingivali and F.nucleatum was 12.5%, 6.25% and 50 % respectively. Conclusion: From results of the study, it is suggested that an ethanolic and aqueous extract of <em>Chia</em> seeds (<em>S.hispanica</em>) has antimicrobial activity against P. gingivalis A. actinomycetemcomitans and F.nucleatum.<strong></strong></p&gt;}, number={4}, journal={International Journal of Ayurveda and Pharma Research}, author={Divyapriya, *G.K. and Veeresh, D.J. and C.Yavagal, Puja}, year={2016}, month={May} }