@article{Aniruddha Das_Yavagal PC_Divya Reddy_2021, title={Antibacterial Efficacy of E. Jambolana (Syzygium Cumini) Seeds Extracts against Periodontal Pathogens: an In-Vitro Study}, volume={9}, url={https://ijapr.in/index.php/ijapr/article/view/2051}, DOI={10.47070/ijapr.v9i10.2051}, abstractNote={<p>Background: Periodontal disease is progressive, inflammation of dento-gingival complex caused by specific periodontal pathogens. Objective<strong>:</strong> To evaluate the minimum inhibitory concentration and zone of inhibition of <em>E. Jambolana (S.cumini)</em> seed extract (aqueous, ethanol and acetone extracts) against <em>P.Gingivalis</em>, <em>F.Nucleatum</em> and A. <em>Actinomycetemcomitans</em> by tube dilution and disc diffusion tests. Methods<strong>:</strong> Aqueous, ethanol and acetone extract of <em>E. Jambolana </em>seeds were prepared. Blood agar media with Hemin, Vitamin K and Kanamycin was used to culture P <em>gingivalis.</em> Crystal violet Erythromycin Blood Agar and Thioglycolate broth with 1% horse serum were used to culture F. nucleatum and A. <em>actinomycetemcomitans </em>respectively. The antibacterial activity of extracts was evaluated by using the disc diffusion method and the Minimum Inhibitory Concentration (MIC) of the test solutions was determined by Tube dilution method. Results<strong>: </strong><em>E. Jambolana</em> seed extracts exhibited antibacterial effect against all three tested periodontal pathogens. Acetone extract of E. <em>Jambolana</em> exhibited more potent activity than the aqueous and ethanol extracts. Minimum Inhibitory concentration of <em>E. Jambolana</em> seed extract against P. <em>gingivalis</em>, was found to be 6.25µl/ml (acetone), against F<em>. nucleatum </em>it was 25µl/ml (acetone) and against A. <em>actinomycetemcomitans</em> it was 12.5µl/ml (acetone). Conclusion<strong>:</strong> <em>Syzygium cumini</em> seeds extracts exhibited antibacterial property against <em>P. gingivalis, A. actinomycetemcomitans </em>and<em> F. nucleatum.</em></p&gt;}, number={10}, journal={International Journal of Ayurveda and Pharma Research}, author={Aniruddha Das and Yavagal PC and Divya Reddy}, year={2021}, month={Nov.}, pages={16-20} }