@article{Manish Kumar Singh_P. Ramesh Bhat_Sweta Tyagi_2020, title={A CLINICAL EVALUATION OF ANTIMICROBIAL ACTIVITY OF GOMUTRA ARKA IN DUSTA VRANA}, volume={8}, url={https://ijapr.in/index.php/ijapr/article/view/1692}, DOI={10.47070/ijapr.v8iSupply2.1692}, abstractNote={<p><em>Vrana chikitsha</em> is very significant in field of Shalya tantra. Healing of <em>Vrana</em> is depends on many factors. Among them growth of microorganism play essential role to slow the process of healing. In <em>Dusta Vrana</em> to improve the healthy granulation and to reduce the colony count of microorganism specific <em>Krimghna</em> <em>dravya </em>is required for that in <em>Shasthi upkrama</em> under <em>Krimighna karma Gomutra Arka</em> is advised. Which has additional property of <em>Lekhana </em>and<em> Ropana. Gomutra Arka </em>is given importance in many oral classical formulation of <em>Ayurveda</em> to treat the<em> Krimi, </em>which is not evaluated for local application on<em> Dusta Vrana </em>yet.</p> <p><strong>Materials and Methods</strong><strong>:</strong> A simple randomized controlled clinical study where 50 patients were equally divided as group A: <em>Gomutra Arka</em> (trial drug) and Group B: Povidone-iodine (standard drug) for 14 days. <strong>Observations and results</strong>: The study result revealed that <em>Gomutra Arka </em>proved to be better Antimicrobial agents than povidone-iodine with a highly significant p-value of 0.04 in comparison to 0.68. It was also established in the study that 10ml<em>Gomutra Arka</em> proved to be more effective on different microorganisms that are <em>Staphylococcus Aureus</em><em>,</em><em> Pseudomonas Aeruginosa</em><em>, </em><em>Shigella</em><em>,</em><em> Salmonella, E. Coli, </em>and<em> Candida Albicans</em>. <strong>Conclusion</strong><strong>:</strong> The <em>Gomutra Arka</em> acts as an antimicrobial agent due to its property like <em>Katu tikta kashya</em> <em>rasa</em> which are <em>Krimighna</em> in nature by this inhibition of microorganism could happen also due to the <em>Ushna tikshna</em> and <em>Kshara guna</em> gives unfavorable environment for bacterial growth. The presence of constituents like copper, aurum, urea, ammonia further helps in antimicrobial activity. Therefore, <em>Gomutra Arka</em> can be used in regular practice as its available at a low cost, affordable and the study proves its efficiency over the Povidone-iodine controlled group.</p&gt;}, number={Supply2}, journal={International Journal of Ayurveda and Pharma Research}, author={Manish Kumar Singh and P. Ramesh Bhat and Sweta Tyagi}, year={2020}, month={Nov.}, pages={27-35} }